Adaptive Frequency Tracking on the ECG Used to Predict the Success of Electrical Cardioversion of Atrial Fibrillation

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Hardware-oriented pruning and quantization of Deep Learning models to detect life-threatening arrhythmias

Alexandre Schmid

Wearable solutions based on Deep Learning (DL) for real-time ECG monitoring are a promising alternative to detect life-threatening arrhythmias. However, DL models suffer of a large memory footprint, which hampers their adoption in portable technologies. Th ...

IEEE2021

POD-Enhanced Deep Learning-Based Reduced Order Models for the Real-Time Simulation of Cardiac Electrophysiology in the Left Atrium

Alfio Quarteroni, Andrea Manzoni

The numerical simulation of multiple scenarios easily becomes computationally prohibitive for cardiac electrophysiology (EP) problems if relying on usual high-fidelity, full order models (FOMs). Likewise, the use of traditional reduced order models (ROMs) ...

FRONTIERS MEDIA SA2021

Acute and Long-Term Effects of Aortic Compliance Decrease on Central Hemodynamics: A Modeling Analysis

Nikolaos Stergiopoulos, Vasiliki Bikia, Georgios Rovas, Stamatia Zoi Pagoulatou

Aortic compliance is an important determinant of cardiac afterload and a contributor to cardiovascular morbidity. In the present study, we sought to provide in silico insights into the acute as well as long-term effects of aortic compliance decrease on cen ...

FRONTIERS MEDIA SA2021

Computational methods for live heart imaging with speed-constrained microscopes

Olivia Mariani

Imaging methods to capture the beating and developing heart inside embryonic animal models such as the zebrafish are a key component for the study of fundamental biological processes such as cardiac birth defects or tissue regeneration. However, live heart ...

EPFL2021

Heart Rate Variability Triangular Index as a Predictor of Cardiovascular Mortality in Patients With Atrial Fibrillation

Jean-Marc Vesin, Vincent Schlageter

Background Impaired heart rate variability (HRV) is associated with increased mortality in sinus rhythm. However, HRV has not been systematically assessed in patients with atrial fibrillation (AF). We hypothesized that parameters of HRV may be predictive o ...

2020

Monitoring of Cardiovascular and Neurological Diseases Using Wearable Devices

Dionisije Sopic

In this thesis, I focus on monitoring of patients suffering from cardiovascular and neurological diseases through the use of wearable devices. The main diseases considered in this thesis are atrial fibrillation (AF), myocardial infarction (MI), and epileps ...

EPFL2020

Outer loop and isthmus in ventricular tachycardia circuits: Characteristics and implications

Alfio Quarteroni, Andrea Manzoni, Luca Dede', Stefano Pagani

BACKGROUND The isthmus of ventricular tachycardia (VT) circuits has been extensively characterized. Few data exist regarding the contribution of the outer loop (OL) to the VT circuit. OBJECTIVE The purpose of this study was to characterize the electrophysi ...

2020

Ventricular response regularity in atrial fibrillation and its relationship to successful catheter ablation

Jean-Marc Vesin, Etienne Pruvot, Adrian Luca

Atrial rate is known to modulate ventricular response during atrial fibrillation (AF). The resulting pulse irregularity translates into widely varying inter-beat intervals (IBIs) extracted from recorded surface electrocardiogram (ECG) activity. In AF, the ...

IEEE2020

Automatic 12-lead ECG Classification Using a Convolutional Network Ensemble

Manoel Horta Ribeiro

The 12-lead electrocardiogram (ECG) is a major diagnostic test for cardiovascular diseases and enhanced automated analysis tools might lead to more reliable diagnosis and improved clinical practice. Deep neural networks are models composed of stacked trans ...

IEEE2020

A Proof of Concept for Computational Fluid Dynamic Analysis of the Left Atrium in Atrial Fibrillation on a Patient-Specific Basis

Alfio Quarteroni, Davide Forti, Filippo Menghini

Atrial fibrillation (AF) is associated with a fivefold increase in the risk of cerebrovascular events, being responsible of 15-18% of all strokes. The morphological and functional remodeling of the left atrium (LA) caused by AF favors blood stasis and, con ...

ASME2020

Modular Design and Optimization of Biomedical Applications for Ultra-Low Power Heterogeneous Platforms

David Atienza Alonso, Luca Benini, Miguel Peon Quiros, Benoît Walter Denkinger, Elisabetta De Giovanni, Simone Machetti

In the last years, remote health monitoring is becoming an essential branch of health care with the rapid development of wearable sensors technology. To meet the demand of new more complex applications and ensuring adequate battery lifetime, wearable senso ...

2020

Nonlinear analysis of right atrial electrograms predicts termination of persistent atrial fibrillation within the left atrium by catheter ablation

Jean-Marc Vesin, Etienne Pruvot, Andréa Buttu, Adrian Luca

The termination of long-standing persistent atrial fibrillation (LS-pAF) can be achieved by stepwise catheter ablation (step-CA) within the left atrium (LA). Our study aims to applying complexity measures derived from nonlinear time series analysis in orde ...

Institute of Physics2016