Amplitude and Phase Fields of Photonic Nanojets

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This work reports on the implementation of a fiber-array with attached microlenses in the balanced-detection Interferometric Cavity-Assisted Photothermal Spectroscopy (ICAPS) scheme, enabling a highly compact probe laser beam path. The sample probe and the ...

Epsilon-near-zero (ENZ) nanophotonic devices with zero permittivity are known to exhibit adiabatic frequency translation via temporal refraction under extracavity excitation by intense light sources, which are however hard to integrate on-chip owing to a h ...

Advancing quantum technologies depends on the precise control of individual quantum systems, the so-called qubits, and the exploitation of their quantum properties. Nowadays, expanding the number of qubits to be entangled is at the core of the developments ...

Second-harmonic generation allows for coherently bridging distant regions of the optical spectrum, with applications ranging from laser technology to self-referencing of frequency combs. However, accessing the nonlinear response of a medium typically requi ...

Optical microscopy is an essential tool for biologists, who are often faced with the need to overcome the spatial and temporal resolution limitations of their devices to capture finer details. As upgrading imaging hardware is expensive, computational metho ...

Nanometric scale size oscillations seem to be a fundamental feature of all living organisms on Earth. Their detection usually requires complex and very sensitive devices. However, some recent studies demonstrated that very simple optical microscopes and de ...

We examine the influence of surface charge on the percolation, gel-point and phase behavior of cellulose nanocrystal (CNC) suspensions in relation to their nonlinear rheological material response. Desulfation decreases CNC surface charge density which lead ...

Controlling and shaping radiation beams is fundamental for a better understanding of radiation-matter interaction and advancing experimental techniques for material characterization at high spatial resolution. In particular, the current trend in the miniat ...

The evolution of the 3D morphology is at the center of many relevant biological processes ranging from cellular differentiation to cancer invasion and metastasis. Microscopy techniques, such as electron microscopy (EM), super-resolution (SR) optical micros ...

The properties of a physical system only exist in relation to its environment. This thesis presents the development of a novel spin qubit scanning probe microscope operating over a wide range of environmental conditions. The qubit, which sits at the heart ...

The present article describes novel massive materials (in the solid phase) based on TEGylated phenothiazine and chitosan that possess great capability to recover mercury ions from constituent aqueous solutions. These were produced by chitosan hydrogelation ...

A microsecond time-resolved version of cryo-electron microscopy (cryo-EM) has recently been introduced to enable observation of the fast conformational motions of proteins. The technique involves locally melting a cryo sample with a laser beam to allow the ...

In this thesis, we study the 3 challenges described above. First, we study different reconstruction techniques and assess the fidelity of each reconstruction results by means of structured illumination and phase conjugation. By reconstructing the 3D refrac ...

The topic of this thesis is the development of new algorithmic reconstruction methods for quantitative phase imaging (QPI). In the past decade, advanced QPI has emerged as a valuable tool to study label-free biological samples and uncover their 3D structur ...

Microscopic visualisation of optically transparent samples has been a topic of interest for several decades. Features such as density or chemical composition can influence the optical phase of transmitted light, and phase contrast can reveal these structur ...

Single-molecule localization microscopy (SMLM) can reveal nanometric details of biological samples, but its high phototoxicity hampers long-term imaging in live specimens. A significant part of this phototoxicity stems from repeated irradiations that are n ...

Optical retrieval of the structure of transparent objects at the nano-scale requires adapted methods capable of probing their interaction with suitable light. Scattering events, for instance, depend on the content and the arrangement of the medium encounte ...

A fluorescence correlation contrast is a straightforward approach to super-resolution imaging. Combining a SPAD array with a novel detection scheme (ISM), we obtain images with up to x4 times resolution enhancement. ...

Autofocus (AF) methods are extensively used in biomicroscopy, for example to acquire timelapses, where the imaged objects tend to drift out of focus. AF algorithms determine an optimal distance by which to move the sample back into the focal plane. Current ...

A modern day light microscope has evolved from a tool devoted to making primarily empirical observations to what is now a sophisticated , quantitative device that is an integral part of both physical and life science research. Nowadays, microscopes are fou ...

Amplitude and Phase Fields of Photonic Nanojets

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Balanced-detection interferometric cavity-assisted photothermal spectroscopy via collimating fiber-array integration

Intracavity Epsilon-Near-Zero Dual-Range Frequency Switch

Electron-beam based nanoscale quantum controls

A chip-scale second-harmonic source via self-injection-locked all-optical poling

Practical computational imaging by use of spatiotemporal light modulation: from simulations to applications in biological microscopy

Mitochondrial nanomotion measured by optical microscopy

Percolation and phase behavior in cellulose nanocrystal suspensions from nonlinear rheological analysis

Quantum engineering and detection of advanced radiation beams

Time-Resolved Scanning Ion Conductance Microscopy and Single-Molecule Spectroscopy

A diamond spin qubit scanning probe microscope

Fractal Analysis of Four Xerogels Based on TEGylated Phenothiazine and Chitosan

Near-atomic resolution reconstructions from in situ revitrified cryo samples

Advanced Techniques in Optical Diffraction Tomography

Nonlinear Inverse Problems in Quantitative Phase Imaging

High sensitivity, incoherent differential imaging

Long-Term, Single-Molecule Imaging of Proteins in Live Cells with Photoregulated Fluxional Fluorophores

Phase calibration of a basic bright-field microscope for 3D metrology of transparent samples at the nanoscale

SPAD array technology enables fluctuation-contrast super-resolution in a confocal microscope

DeepFocus: a Few-shot Microscope Slide Auto-Focus using a Sample Invariant CNN-based Sharpness Function

QUAREP-LiMi: A community-driven initiative to establish guidelines for quality assessment and reproducibility for instruments and images in light microscopy