Publications associées à Surface-based characteristics of the cerebellar cortex visualized with ultra-high field MRI

Publications associées (33)

The hindbrain and cortico-reticular pathway in adolescent idiopathic scoliosis

AIM: To characterise the corticoreticular pathway (CRP) in a case -control cohort of adolescent idiopathic scoliosis (AIS) patients using high -resolution slice -accelerated readoutsegmented echo -planar diffusion tensor imaging (DTI) to enhance the discri ...

W B Saunders Co Ltd2024

Task-driven neural network models predict neural dynamics of proprioception: Neural network model weights

Alexander Mathis, Alberto Silvio Chiappa, Alessandro Marin Vargas, Axel Bisi

Proprioception tells the brain the state of the body based on distributed sensors in the body. However, the principles that govern proprioceptive processing from those distributed sensors are poorly understood. Here, we employ a task-driven neural network ...

Zenodo2024

Context-Aware Monitoring of Hand Motor Primitives in Daily Life Activities: A Pathway to Objectively Assess Rehabilitation of Patients with Upper-Limb Neurological Impairment

Yasaman Izadmehr

The hands, our silent performers in daily life, face overwhelming challenges when neurological impairments disrupt the simple tasks that compose our daily symphony. This thesis unveils a comprehensive framework for the objective monitoring of upper-limb re ...

EPFL2024

The Cerebellum and Cognitive Function: Anatomical Evidence from a Transdiagnostic Sample

Farnaz Delavari

Multiple lines of evidence across human functional, lesion, and animal data point to a cerebellar role, in particular of crus I, crus II, and lobule VIIB, in cognitive function. However, a mapping of distinct facets of cognitive function to cerebellar stru ...

Springer2023

Novel personalized treatment strategy for patients with chronic stroke with severe upper-extremity impairment: The first patient of the AVANCER trial

Friedhelm Christoph Hummel, Takuya Morishita, Maximilian Jonas Wessel, Elena Beanato, Sylvain Jean-François Harquel, Andrea Crema, Giorgia Giulia Evangelista, Claudia Bigoni, Sarah Bernardina Zandvliet, Julie Loréline Valériane Hervé, Meltem Oflar

Background: Around 25% of patients who have had a stroke suffer from severe upper-limb impairment and lack effective rehabilitation strategies. The AVANCER proof-of-concept clinical trial (NCT04448483) tackles this issue through an intensive and personaliz ...

CELL PRESS2023

Cortical alterations after very preterm birth and the association with socio-emotional abilities from childhood to early adolescence

Jean-Philippe Thiran, Elda Fischi Gomez, Vanessa Siffredi

Very preterm birth (VPT;

2023

New insights into rodent brain microstructure and metabolism in hepatic encephalopathy

Jessie Julie Mosso

Type C hepatic encephalopathy (HE) is a severe neuropsychiatric complication of chronic liver disease, for which the prognosis is poor in the absence of liver transplantation. Cirrhosis in type C HE leads to a toxic accumulation of ammonia in the blood, wh ...

EPFL2023

Tonic pain alters functional connectivity of the descending pain modulatory network involving amygdala, periaqueductal gray, parabrachial nucleus and anterior cingulate cortex

Anne-Christine Schmid

Introduction: Resting state functional connectivity (FC) is widely used to assess functional brain alterations in patients with chronic pain. However, reports of FC accompanying tonic pain in pain-free persons are rare. A network we term the Descending Pai ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2022

Pum2 and TDP-43 refine area-specific cytoarchitecture post-mitotically and modulate translation of Sox5, Bcl11b, and Rorb mRNAs in developing mouse neocortex

Nagammal Neelagandan

In the neocortex, functionally distinct areas process specific types of information. Area identity is established by morphogens and transcriptional master regulators, but downstream mechanisms driving area-specific neuronal specification remain unclear. He ...

eLIFE SCIENCES PUBL LTD2022

MP-PCA denoising for diffusion MRS data: promises and pitfalls

Cristina Ramona Cudalbu Moldovan, Dunja Simicic, Jessie Julie Mosso

Diffusion-weighted (DW) magnetic resonance spectroscopy (MRS) suffers from a lower signal to noise ratio (SNR) compared to conventional MRS owing to the addition of diffusion attenuation. This technique can therefore strongly benefit from noise reduction s ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2022

Anatomical and functional characterization of neocortical circuits involved in transforming whisker sensory processing into goal-directed licking

Georgios Foustoukos

The choice of an action upon perception of an external stimulus, arriving at a sensory organ of an animal, depends on previous experiences and outcomes throughout its life. In the rodent brain, the underlying mechanisms involved in simple sensorimotor tran ...

EPFL2022

Age- and gender-related differences in brain tissue microstructure revealed by multi-component T2 relaxometry

Erick Jorge Canales Rodriguez

In spite of extensive work, inconsistent findings and lack of specificity in most neuroimaging techniques used to examine age- and gender-related patterns in brain tissue microstructure indicate the need for additional research. Here, we performed the larg ...

2021

Elezanumab, a human anti-RGMa monoclonal antibody, promotes neuroprotection, neuroplasticity, and neurorecovery following a thoracic hemicompression spinal cord injury in non-human primates

Grégoire Courtine, Quentin Barraud

Spinal cord injury (SCI) is a devastating condition characterized by loss of function, secondary to damaged spinal neurons, disrupted axonal connections, and myelin loss. Spontaneous recovery is limited, and there are no approved pharmaceutical treatments ...

2021

Target cell-type specificity of a cortico-amygdala long range synaptic connection

Ayah Khubieh

An important function of the brain is to analyze sensory information, and to modulate animal behaviour according to previous experience. During processes of emotional learning, sensory percepts with a reinforcing quality, also called unconditioned stimuli ...

EPFL2021

Long term effects of peripubertal stress on excitatory and inhibitory circuits in the prefrontal cortex of male and female mice

Maria del Carmen Sandi Perez

The impact of stressful events is especially important during early life, because certain cortical regions, especially the prefrontal cortex (PFC), are still developing. Consequently, aversive experiences that occur during the peripubertal period can cause ...

2021

Metabolic and hemodynamic changes in the activated human brain and cerebellar organisation measured by MRS/MRl at 7 Tesla

Yohan Boillat

Although less often investigated than the positive blood-oxygen-level-dependent (BOLD) signal, a negative BOLD signal has also been observed under certain conditions, which could have a neuronal origin. To further investigate the negative BOLD signal from ...

EPFL2020

Brainstem Correlates of a Cold Pressor Test Measured by Ultra-High Field fMRI

Dimitri Nestor Alice Van De Ville, Sandra Elisabete Monney, Olivier Benoit Thomas Reynaud, Domenica Bueti

Introduction Modern imaging techniques such as blood oxygen level-dependent (BOLD) functional magnetic resonance imaging (fMRI) allow the non-invasive and indirect measurement of brain activity. Whether changes in signal intensity can be detected in small ...

2020

Anatomically and functionally distinct thalamocortical inputs to primary and secondary mouse whisker somatosensory cortices

Carl Petersen, Georgios Foustoukos, Berat Semihcan Sermet, Sami El-Boustani

Subdivisions of mouse whisker somatosensory thalamus project to cortex in a region-specific and layer-specific manner. However, a clear anatomical dissection of these pathways and their functional properties during whisker sensation is lacking. Here, we us ...

Nature Publishing Group2020

Human Cochlear Nucleus on 7 Tesla Diffusion Tensor Imaging: Insights Into Micro-anatomy and Function for Auditory Brainstem Implant Surgery

Nicolas Vachicouras

Objective:The cochlear nucleus (CN) is the target of the auditory brainstem implant (ABI). Most ABI candidates have Neurofibromatosis Type 2 (NF2) and distorted brainstem anatomy from bilateral vestibular schwannomas. The CN is difficult to characterize as ...

LIPPINCOTT WILLIAMS & WILKINS2020

Whole-body somatotopic maps in the cerebellum revealed with 7T fMRI

Wietske Van der Zwaag, Yohan Boillat

The cerebellum is known to contain a double somatotopic body representation. While the anterior lobe body map has shown a robust somatotopic organization in previous fMRI studies, the representations in the posterior lobe have been more difficult to observ ...

2020