Altered sensory processing and dendritic remodeling in hyperexcitable visual cortical networks

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Background Visual impairment (VI) significantly impacts quality of life, particularly in autonomous pedestrian navigation. Limitations in independent navigation lead to frustration, diminished confidence, and risks to bodily integrity for individuals with ...

In the last few years, stroke ranked as the second most common cause of death and is the third most significant condition affecting disability-adjusted life years (DALYs) worldwide. Being the most prevalent and quality of life impacting post-stroke symptom ...

Neural decoding of the visual system is a subject of research interest, both to understand how the visual system works and to be able to use this knowledge in areas, such as computer vision or brain-computer interfaces. Spike-based decoding is often used, ...

In humans and animals, surprise is a physiological reaction to an unexpected event, but how surprise can be linked to plausible models of neuronal activity is an open problem. We propose a self-supervised spiking neural network model where a surprise signa ...

Proprioception tells the brain the state of the body based on distributed sensors in the body. However, the principles that govern proprioceptive processing from those distributed sensors are poorly understood. Here, we employ a task-driven neural network ...

The temporal variability of the thalamus in functional networks may provide valuable insights into the pathophysiology of schizophrenia. To address the complexity of the role of the thalamic nuclei in psychosis, we introduced micro-co-activation patterns ( ...

Background and Hypothesis For a long time, it was proposed that schizophrenia (SCZ) patients rely more on sensory input and less on prior information, potentially leading to reduced serial dependence-ie, a reduced influence of prior stimuli in perceptual t ...

Purpose of review: To review recent advances in the field of seizure detection in ambulatory patients with epilepsy. Recent findings: Recent studies have shown that wrist or arm wearable sensors, using 3D-accelerometry, electrodermal activity or photopleth ...

Electrical stimulation of the visual nervous system could improve the quality of life of patients affected by acquired blindness by restoring some visual sensations, but requires careful optimization of stimulation parameters to produce useful perceptions. ...

The decline of motor ability is a hallmark feature of aging and is accompanied by degeneration of motor synaptic terminals. Consistent with this, Drosophila motor synapses undergo characteristic age -dependent structural fragmentation co -incident with dim ...

Epilepsy, a major neurological disease, requires careful diagnosis and treatment. However, the detection of epileptic seizures remains a significant challenge. Current clinical practice relies on expert analysis of EEG signals, a process that is time-consu ...

Implanted medical devices (IMDs) have been widely developed to support the monitoring and recording of biological data inside the body or brain. Wirelessly powered IMDs, a subset of implantable electronics, have been proposed to eliminate the limitations r ...

Subcortical brain structures such as the basal ganglia or the thalamus are involved in regulating motor and cognitive behavior. However, their contribution to perceptual consciousness is still unclear, due to the inherent difficulties of recording subcorti ...

Animals, including humans, exhibit a remarkable variety of complex behaviours. How the nervous system controls all these behaviours ranging from simple, stereotyped movements to flexible, adaptive actions is a central questions of neuroscience. One of the ...

Background Each year, five million people are left disabled after stroke. Upper -extremity (UE) dysfunction is a leading problem. Neuroplasticity can be enhanced by non-invasive brain stimulation (NIBS) but evidence from large, randomized multicenter trial ...

While humans are known to have several premotor cortical areas, secondary motor cortex (M2) is often considered to be the only higher -order motor area of the mouse brain and is thought to combine properties of various human premotor cortices. Here, we sho ...

Traditionally, studies in schizophrenia research employ a single experimental paradigm. The results typically demonstrate a significant difference between patients and controls. Subsequent studies aim to describe the underlying abnormal mechanism at the ge ...

The reported rate of the occurrence of unilateral spatial neglect (USN) is highly variable likely due to the lack of validity and low sensitivity of classical tools used to assess it. Virtual reality (VR) assessments try to overcome these limitations by pr ...

Neuroprostheses have been used clinically for decades, to help restore or preserve brain functions, when pharmaceutical treatments are inefficient. Although great progress in the field has been made over the years to interface with the nervous system, surf ...

Social behaviors such as cooperation are crucial for mammals. A deeper knowledge of the neuronal mechanisms underlying cooperation can be beneficial for people suffering from pathologies with impaired social behavior. Our aim was to study the brain activit ...

Altered sensory processing and dendritic remodeling in hyperexcitable visual cortical networks

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Challenges and Opportunities of the Human-Centered Design Approach: Case Study Development of an Assistive Device for the Navigation of Persons With Visual Impairment

Probing and modulating inter-areal coupling in the cortical visual motion processing pathway with non-invasive brain stimulation

Predicting Visual Stimuli From Cortical Response Recorded With Wide-Field Imaging in a Mouse

Fast adaptation to rule switching using neuronal surprise

Task-driven neural network models predict neural dynamics of proprioception: Neural network model weights

Thalamic contributions to psychosis susceptibility: Evidence from co-activation patterns accounting for intra-seed spatial variability (μCAPs)

Intact Serial Dependence in Schizophrenia: Evidence from an Orientation Adjustment Task

Ambulatory seizure detection

Decoding electroencephalographic responses to visual stimuli compatible with electrical stimulation

Trio preserves motor synapses and prolongs motor ability during aging

Resource-Efficient Continual Learning for Personalized Online Seizure Detection

Integrated Wireless Power, Data Communication, and Thermal Sensing System for Autonomous Multisite Brain Implants

Subcortical correlates of consciousness with human single neuron recordings

Uncovering interactions between Descending Neurons as a functional principle of behavioural control

Efficacy and safety of transcranial direct current stimulation to the ipsilesional motor cortex in subacute stroke (NETS): a multicenter, randomized, double-blind, placebo-controlled trial

The mouse motor system contains multiple premotor areas and partially follows human

Variability is the rule: Neurophysiology and contextual visual processing in schizophrenia

An immersive virtual reality tool for assessing left and right unilateral spatial neglect

Unraveling behavior and cortical signals to guide the development of soft neuroprostheses for auditory restoration and spreading depolarization

Involvement of prelimbic cortex neurons and related circuits in the acquisition of a cooperative learning by pairs of rats