Adapt or Perish: Evolutionary Rescue in a Gradually Deteriorating Environment

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Background: Reproductive isolation can result from adaptive processes (e.g., ecological speciation and mutation-order speciation) or stochastic processes such as "system drift" model. Ecological speciation predicts barriers to gene flow between populations ...

Climate changes influence lake hydrodynamics and radiation levels and thus may affect the fate and transport of waterborne pathogens in lakes. This study examines the impact of climate change on the fate, transport, and associated risks of four waterborne ...

Post-translational modifications (PTMs) play a pivotal role in regulating protein structure, interaction, and function. Aberrant PTM patterns are associated with diseases. Moreover, individual PTMs have a complex interaction with each other, known as PTM c ...

Owing to stochastic fluctuations arising from finite population size, known as genetic drift, the ability of a population to explore a rugged fitness landscape depends on its size. In the weak mutation regime, while the mean steady-state fitness increases ...

This article explores how the logic underlying modal practices tends to modulate the population’s responsiveness to improvements in global transport supply. Based on a quantitative survey conducted in 2018–2019 among the working population of the cantons o ...

We introduce a reconfigurable medium for the manipulation of elastic propagation properties of Lamb waves. It is based on a shape memory polymer (SMP) with temperature-dependent Young's modulus. Waves are excited by a laser pulse and detected by a laser vi ...

Long-term consumption of lipid-rich foods can contribute to common metabolic diseases and systemic low-grade inflammation. However, dietary responses and the development of non-communicable diseases are shaped by genetic factors and gene-by-environment int ...

The terminology of neurological disorders encompasses a range of serious illnesses (e.g., epilepsy, Alzheimer's disease) leading to morbidity, disability, and stigma. Epilepsy alone affects over 50 million people worldwide, and these figures are rising as ...

As the world’s population grows in cities, urban dwellers spend a large amount of time inside their home, making housing health ever more important. Critical for residents’ health, the interactions between indoor residential environments and outdoor enviro ...

Waste treatment is a complex procedure that comprises multidimensional aspects. The challenges posed by the energy transition and international protocols emphasize the role of waste in its material and energy dimension. With an increasing population and li ...

The multidimensionality of the stress response has shown the complexity of this phenomenon and therefore the impossibility of finding a unique biomarker among the physiological variables related to stress. An experimental study was designed and performed t ...

An artificial floods program has been implemented on the Sarine residual flow reach, downstream of the Rossens dam. Two artificial floods were released in 2016 (coupled with sediment augmentation) and in 2020. A natural flood occurred in 2021. The indicato ...

Dysregulations in cholesterol metabolism are associated with neurodegenerative and vascular pathologies, and dementia. Diet-derived plant sterols (phytosterols) have cholesterol-lowering, anti-inflammatory, and antioxidant properties and may interfere with ...

During fear learning, defensive behaviors like freezing need to be finely balanced in the presence or absence of threat-predicting cues (conditioned stimulus, CS). Nevertheless, the circuits underlying such balancing are largely unknown. Here, we investiga ...

The study of insular populations was key in the development of evolutionary theory. The successful colonisation of an island depends on the geographic context, and specific characteristics of the organism and the island, but also on stochastic processes. A ...

The Montecristo wild goat is an endangered feral population that has been on the homonymous island in the Tuscan Archipelago since ancient times. The origins of Montecristo goats are still debated, with authors dating their introduction either back to Neol ...

We address for the first time the problem of correcting group discriminations within a score function, while minimizing the individual error. Each group is described by a probability density function on the set of profiles. We first solve the problem analy ...

In a context where daily car use is a spontaneous and habitual choice for a wide majority of the population, the quality of the alternatives to individual motorized vehicles is a major factor in encouraging modal shift. The ease of access to public transpo ...

The presence of viruses in recreational water can present a risk for human health and wastewater effluent is a source of virus in the environment. Their persistence in the environment influences their probability to find a new host. Studies have shown that ...

Evolutionary diversity in species can arise in many ways, including local adaptation. Despite the global importance of tropical forest ecosystems, few studies have explored patterns of local adaptation in tropical tree species. We investigated population g ...

Adapt or Perish: Evolutionary Rescue in a Gradually Deteriorating Environment

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Reproductive isolation arises during laboratory adaptation to a novel hot environment

Waterborne Virus Transport and Risk Assessment in Lake Geneva Under Climate Change

Investigating the intra-molecular and inter-molecular effects of post-translational modifications on intrinsically disordered protein regions and structured protein regions

Impact of population size on early adaptation in rugged fitness landscapes

Analysing the potential for modal shiftbased on the logic of modal choice

Optimization of elastic wave propagation in a reconfigurable medium by genetic algorithms with adaptive mutation probability

Identifying genetic and dietary modulators of metabolic disorders using systems genetics

Real-time Personalized Monitoring of Neurological Disorders on Wearable Systems

Housing, street and health: a new systemic research framework

Decision support methodology for waste-to-value process integration

Psychosomatic response to acute emotional stress in healthy students

Effects of water releases and sediment supply on a residual flow reach

Plant sterols and cholesterol metabolism are associated with five-year cognitive decline in the elderly population

A striatal circuit balances learned fear in the presence and absence of sensory cues

Genomic consequences of colonisation, migration and genetic drift in barn owl insular populations of the eastern Mediterranean

The SNP-Based Profiling of Montecristo Feral Goat Populations Reveals a History of Isolation, Bottlenecks, and the Effects of Management

Removing Algorithmic Discrimination (With Minimal Individual Error)

Assessment of the Bus Transit Network: A Perspective from the Daily Activity-Travel Organization of Travelers

Effect of wastewater treatment and environmental exposure on an enterovirus population

Population structure and signals of local adaptation in Eugenia uniflora (Myrtaceae), a widely distributed species in the Atlantic Forest