Dual orexin receptor antagonists - promising agents in the treatment of sleep disorders

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The human brain is a complex and dynamic physiological system that can be considered as a network of reciprocally interconnected systems localized in different brain regions. To fully characterize the brain's complex dynamics, it is essential to investigat ...

Reinforcement feedback can improve motor learning, but the underlying brain mechanisms remain underexplored. In particular, the causal contribution of specific patterns of oscillatory activity within the human striatum is unknown. To address this question, ...

Obesity represents a significant public health concern and is linked to various comorbidities and cognitive impairments. Previous research indicates that elevated body mass index (BMI) is associated with structural changes in white matter (WM). However, a ...

The growing global obesity issue emphasizes the importance of understanding its health implications. Previous research has identified consistent alterations in gray matter (GM) volume in connection with obesity. Given the various implications of distinct f ...

The reported rate of the occurrence of unilateral spatial neglect (USN) is highly variable likely due to the lack of validity and low sensitivity of classical tools used to assess it. Virtual reality (VR) assessments try to overcome these limitations by pr ...

Subcortical brain structures such as the basal ganglia or the thalamus are involved in regulating motor and cognitive behavior. However, their contribution to perceptual consciousness is still unclear, due to the inherent difficulties of recording subcorti ...

Implanted medical devices (IMDs) have been widely developed to support the monitoring and recording of biological data inside the body or brain. Wirelessly powered IMDs, a subset of implantable electronics, have been proposed to eliminate the limitations r ...

Objective. Selective neuromodulation of deep brain regions has for a long time only been possible through invasive approaches, because of the steep depth-focality trade-off of conventional non-invasive brain stimulation (NIBS) techniques. Approach. An appr ...

Background: Understanding why only a subset of trauma-exposed individuals develop posttraumatic stress disorder is critical for advancing clinical strategies. A few behavioral (deficits in fear extinction) and biological (blunted glucocorticoid levels, sma ...

All functions we use in our everyday life depend on a complex interplay between both cortical and subcortical brain areas, communicating in between each others. When a region is affected by either an accident, aging or neurodegenerative diseases, the whole ...

The outstanding information processing capacity of the brain relies on numerous molecular mechanisms. It is an extremely energy-expensive function, which involves specialization and collaboration of different cell types. A common framework to study the com ...

The dorsomedial prefrontal cortex/dorsal anterior cingulate cortex (dmPFC/dACC) is a brain area subject to many theories and debates over its function(s). Even its precise anatomical borders are subject to much controversy. In the past decades, the dmPFC/d ...

Recent years have seen considerable progress in understanding brain function, and in modulating it through real-time fMRI neurofeedback (NF). Inspired by these advances, paired with the unique possibility of inducing the clinically relevant Presence Halluc ...

Reading out neuronal activity from three-dimensional (3D) functional imaging requires segmenting and tracking individual neurons. This is challenging in behaving animals if the brain moves and deforms. The traditional approach is to train a convolutional n ...

Although adults and children differ in self-vs.-other perception, a developmental perspective on this discriminative ability at the brain level is missing. This study examined neural activation for self-vs.-other in a sample of 39 participants spanning fou ...

"Ensure healthy lives and promote well-being for all at all ages" is the third sustainable development goal for the United Nations Agenda of 2030. This doctoral thesis fully embodied this objective by targeting stroke, a leading cause of death and disabili ...

The brain is composed of several anatomically clearly separated structures. This parcellation is often extended into the isocortex, based on anatomical, physiological or functional differences. Here, we derive a parcellation scheme based purely on the spat ...

The brain and behavior are under energetic constraints, limited by mitochondrial energy transformation capacity. However, the mitochondria-behavior relationship has not been systematically studied at a brain-wide scale. Here we examined the association bet ...

Type C hepatic encephalopathy (HE) is a severe neuropsychiatric complication of chronic liver disease, for which the prognosis is poor in the absence of liver transplantation. Cirrhosis in type C HE leads to a toxic accumulation of ammonia in the blood, wh ...

This work is dedicated to the systematic investigation of wind turbine wakes under the effect of pressure gradients. Wind tunnel experiments are carried out with a wind turbine positioned on straight ramps of increasing angle such that it experiences an ap ...

Dual orexin receptor antagonists - promising agents in the treatment of sleep disorders

Chattez avec Graph Search

A Spatiotemporal Analysis of Brain Dynamics, a New Feature for Sleep and Seizure State Discrimination

Non-invasive stimulation of the human striatum disrupts reinforcement learning of motor skills

White adipose tissue distribution and amount are associated with increased white matter connectivity

The interplay between white adipose tissue, adipokines, and structural gray matter changes

An immersive virtual reality tool for assessing left and right unilateral spatial neglect

Subcortical correlates of consciousness with human single neuron recordings

Integrated Wireless Power, Data Communication, and Thermal Sensing System for Autonomous Multisite Brain Implants

Safety, tolerability and blinding efficiency of non-invasive deep transcranial temporal interference stimulation: first experience from more than 250 sessions

Blunted Glucocorticoid Responsiveness to Stress Causes Behavioral and Biological Alterations That Lead to Posttraumatic Stress Disorder Vulnerability

Noninvasive deep brain stimulation to modulate human behavior by means of transcranial temporal interference electrical stimulation

Molecular reconstruction and simulation of the Neuron-Glia-Vasculature system

Debates on the dorsomedial prefrontal/dorsal anterior cingulate cortex: insights for future research

Neuroengineering of hallucinations through fMRI neurofeedback: Understanding and modulating neural dynamics for the control of hallucinations in health and disease

Automated neuron tracking inside moving and deforming C. elegans using deep learning and targeted augmentation

Me, Myself, and I: Neural Activity for Self versus Other across Development

Combination of Neurotechnologies Towards Personalized Neurorehabilitation for Stroke Patients

A parcellation scheme of mouse isocortex based on reversals in connectivity gradients

Brain mitochondrial diversity and network organization predict anxiety-like behavior in male mice

New insights into rodent brain microstructure and metabolism in hepatic encephalopathy

An experimental and analytical study of wind turbine wakes under pressure gradient