Publications associées à Synthesis of D- and L-erythro 1,5-dithiopent-1-enopyranoside sulfonium salts and their evaluation as glycosidase inhibitors

Publications associées (23)

Ring-Opening Reactions of Aminocyclopropanes and Aminocyclobutanes

Nitrogen-containing compounds are an important class of molecules in medicinal chemistry, chemical biology, biochemistry, material sciences or environmental sciences. Organic nitrogen occurs in many forms, ranging from small building blocks such as urea, a ...

EPFL2022

Organocatalysts in C-N Bond Forming Reactions of Amines with CO2

Martin Hulla

The thesis describes a simple approach for N-formylation of amines with CO2 and hydrosilane reducing agents, the use of organic salts as N-formylation catalysts, their physical properties required for high catalytic activity and their role in the catalytic ...

EPFL2019

Many touchings force many crossings

János Pach

Given n continuous open curves in the plane, we say that a pair is touching if they have finitely many interior points in common and at these points the first curve does not get from one side of the second curve to its other side. Otherwise, if the two cur ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2019

FeOx magnetization enhancing E-coli inactivation by orders of magnitude on Ag-TiO2 nanotubes under sunlight

César Pulgarin, Juan Kiwi, Arnaud Magrez, Sami Rtimi, Ivica Zivkovic, Stefanos Giannakis

Drastic bacterial enhancement was observed when the Ag(3%)-TiO2 nanotubes were modified with FeOx (3%) magnetic oxide. On bare TiO2- nanotubes a reduction of 0.21og(10)CFU was observed within one hour under simulated low intensity solar light. Under simila ...

Elsevier2017

BCl3-Mediated Ene Reaction of Sulfur Dioxide and Unfunctionalized Alkenes

Pierre Vogel, Dean Markovic

The first ene reactions of SO2 and unfunctionalized alkenes are reported. Calculations suggest that the endergonic ene reactions of SO2 with alkenes can be used to generate beta,gamma-unsaturated sulfinyl and sulfonyl compounds. Indeed, in the presence of ...

2010

Studying sulfur functional groups in Norway spruce year rings using S L-edge total electron yield spectroscopy

Christian Ludwig, Rudolf Paul Wilhelm Jozef Struis

Profiles of the major sulfur functional groups in mature Norway spruce wood tissue have been established for the first time. The big challenge was the development of a method suitable for sulfur speciation in samples with very low sulfur content (

Elsevier2008

Influence of chemical substitutions on the charge instability of BaVS3

Helmuth Berger, László Forró, Ana Akrap

We study the influence of Sr substitutions on the structural counterpart of the MI transition of BaVS3. When Sr content increases, the commensurate CDW modulation of pure BaVS3 is changed into an incommensurate short range modulation that we attribute to a ...

2008

Uranium(IV) Terminal Hydrosulfido and Sulfido Complexes: The Nature of the Uranium–Sulfur Bond

Marinella Mazzanti, Julie Renée Michelle Andrez

Herein, we report the synthesis and characterization of a series of terminal uranium(IV) hydrosulfido and sulfido complexes, supported by the hexadentate, tacn-based ligand framework (Ad,MeArO)3tacn3– (= trianion of 1,4,7-tris(3-adamantyl-5-methyl-2-hydrox ...

2016

Organic-sulfur poisoning of solid oxide fuel cell operated on bio-syngas

Jan Van Herle, Christian Ludwig, Stefan Diethelm, Hossein Madi

This study experimentally analyzes the performance and degradation issues of an anode supported (AS) Ni-YSZ solid oxide fuel cell exposed to thiophene (C4H4S). The impact of this organic sulfur compound on the performance of SOFC Ni-YSZ anodes is reported ...

Elsevier2016

Reaction between propargyl radical and 1,3-butadiene to form five to seven membered rings. Theoretical study

Daniela Trogolo

Propargyl radical addition to 1,3-butadiene seems to be a promising channel to form 5-, 6-, and 7-membered rings. These are important steps in the growth of polycyclic aromatic hydrocarbons and soot platelets. The reaction mechanism, involving 97 intermedi ...

Elsevier Science Inc2016

Chemistry and climate interactions : development and evaluation of a coupled chemistry-aerosol-climate model

Luca Pozzoli

Atmospheric trace gases and aerosols and climate interact in many ways. A quantitative assessment of the influence of trace gases and aerosols on climate can only be achieved if the interactions and feedbacks among these three major components are accounte ...

EPFL2007

Synthesis of Alkynylated Heterocycles by Direct C-H Alkynylation or Domino Alkynylation Reactions

Yifan Li

Heterocycles are important compounds in organic chemistry. To introduce functional groups on heterocycles or synthesize functionalized heterocycles stays a hot topic of research. Among all the functional groups, alkynes attracted a lot of attention not onl ...

EPFL2016

Wittig rearrangement of lithiated allyl aryl ethers: a mechanistic study

A -75 DegC, alpha-lithiated allyl Ph ether undergoes mainly the Wittig rearrangement to afford, after acidic hydrolysis, 1-phenyl-2-propen-1-ol as the main product. A second metalation taking place at one of the ortho positions is the sole competing side r ...

2006

The reactivity of 2-fluoro- and 2-chloropyridines toward sodium ethoxide: Factors governing the rates of nucleophilic (het)aromatic substitutions

Thierry Rausis

The relative displacement rates of the halide substituent from 2-fluoro- and 2-chloropyridines by EtONa in EtOH at +25 Deg were assessed by competition kinetics. The 2-fluoropyridine reacts 320 times faster than the chloro analog. A CF3 group increases the ...

2005

Structure and Properties of the Precursor/Successor Complex and Transition State of the CrCl2+/Cr2+ Electron Self-Exchange Reaction via the Inner-Sphere Pathway

François Rotzinger

The electron self-exchange reaction CrCl(OH2)5(2+) + Cr(OH2)6(2+) -> Cr(OH2)(6)(2+) + CrCl(OH2)(5)(2+), proceeding via the inner-sphere pathway, was investigated with quantum-chemical methods. Geometry and vibrational frequencies of the precursor/successor ...

American Chemical Society2014

Fluorine in an heteroaromatic context : functionalization of halopyridines

Thierry Rausis

The organometallic approach to the functionalization of arenes and heteroarenes has recently been investigated by our group introducing modifications of the standard methods. This includes, in particular, the basicity-driven heavy halogen migration, which ...

EPFL2005

Sulfur containing organic compounds in the raw producer gas of wood and grass gasification

Christian Ludwig, Tilman J. Schildhauer

The detailed description of gas streams in biomass gasification plants is necessary for the correct design and operation of these units. Sulfur containing compounds are usually present in biomass gasification gas, since sulfur is typically found in the fee ...

Elsevier2014

Evaluation of the in vitro anticancer activity of cyclometalated half-sandwich rhodium and iridium complexes coordinated to naphthaldimine-based poly(propyleneimine) dendritic scaffolds

Paul Joseph Dyson, Catherine Marie Amélie Clavel, Fabio Edafe

The development of cyclometalated rhodium and iridium complexes from first-and second-generation naphthaldimine-based poly(propyleneimine) dendrimer scaffolds of the type, DAB-(NH2)(n) (where n = 4 or 8, DAB = diaminobutane) has been accomplished. Four met ...

Elsevier Science Sa2014

Regiochemically flexible substitutions of di-, tri-, and tetrahalopyridines: the trialkylsilyl trick

Carla Bobbio, Thierry Rausis

2,4-Difluoropyridine, 2,4-dichloropyridine, 2,4,6-trifluoropyridine, 2,4,6-trichloropyridine and 2,3,4,6-tetrafluoropyridine react with std. nucleophiles exclusively at the 4-position under halogen displacement. However, the regioselectivity can be complet ...

2005

One-pot synthesis of 1-aryl-3-methyl-1,3-dienes using methallyl(trimethyl)silane and aldehydes and their low temperature (Z)->(E) isomerization induced by sulfur dioxide

Pierre Vogel

2-Methylprop-2-ene-1-sulfonyl fluorides can be easily prepared via the ene reaction of methallylsilanes and SO2. In the presence of a base, aldehydes and 2-methylprop-2-ene-1-sulfonyl fluorides give 1.3-(E) and (Z)-dienes. Their (Z) --> (E) isomerization b ...

2005