Transient gene expression: A novel mammalian cell-based technology for recombinant protein production. A historical and technical perspective

Florian Maria Wurm, David Hacker, Lucia Baldi Unser, Martin Jordan, Philippe Pierre Girard, Natalie Muller, Jason Wright, Frédéric Grosjean
2002
Conference Papers

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Florian Maria Wurm, David Hacker, Lucia Baldi Unser, Martin Jordan, Philippe Pierre Girard, Natalie Muller, Jason Wright, Frédéric Grosjean
2002
Conference Papers

Source officielle

Publications associées (5)

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https://infoscience.epfl.ch/entities/publication/6b8d13a2-2a4e-4212-b21f-b0c6bba22e68

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Publications associées (5)

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Quantitative studies of gene expression in have shown widespread variability in transcript and protein product abundance at the single-cell level. Such fluctuations in gene expression have been shown to lead to heterogeneous cellular responses and phenotyp ...

EPFL2018

Rapid recombinant protein production from piggyBac transposon-mediated stable CHO cell pools

Florian Maria Wurm, David Hacker, Lucia Baldi Unser, Zuzana Kadlecova, Sowmya Balasubramanian

Heterogeneous populations of stably transfected cells (cell pools) can serve for the rapid production of moderate amounts of recombinant proteins. Here, we propose the use of the piggyBac (PB) transposon system to improve the productivity and long-term sta ...

Elsevier2015

Assessing the role of Hes1 and identification of target genes in human and murine T-ALL

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The Notch signalling pathway is an ancient cell signalling mechanism that enables short-range communications between cells and controls a broad spectrum of cell fates and developmental processes. In the haematopoietic system Notch signalling has been linke ...

EPFL2014