Imaging of prolonged BOLD response in the somatosensory cortex of the rat

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Combination of Neurotechnologies Towards Personalized Neurorehabilitation for Stroke Patients

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"Ensure healthy lives and promote well-being for all at all ages" is the third sustainable development goal for the United Nations Agenda of 2030. This doctoral thesis fully embodied this objective by targeting stroke, a leading cause of death and disabili ...

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Modeling and simulation of neocortical micro- and mesocircuitry. Part II: Physiology and experimentation

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Noninvasive theta-burst stimulation of the human striatum enhances striatal activity and motor skill learning

Elena Beanato, Pablo Maceira Elvira, Esra Neufeld, Friedhelm Christoph Hummel, Takuya Morishita, Maximilian Jonas Wessel, Chang-Hyun Park, Traian Popa, Pierre Theopistos Vassiliadis, Pauline Menoud, Fabienne Windel

The stimulation of deep brain structures has thus far only been possible with invasive methods. Transcranial electrical temporal interference stimulation (tTIS) is a novel, noninvasive technology that might overcome this limitation. The initial proof-of-co ...

Nature Portfolio2023

Noninvasive deep brain stimulation to modulate human behavior by means of transcranial temporal interference electrical stimulation

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All functions we use in our everyday life depend on a complex interplay between both cortical and subcortical brain areas, communicating in between each others. When a region is affected by either an accident, aging or neurodegenerative diseases, the whole ...

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Enhancement of brain atlases with region-specific coordinate systems: flatmaps and barrel column annotations

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Digital brain atlases define a hierarchy of brain regions and their locations in three-dimensional space. They provide a standard coordinate system in which diverse datasets can be integrated for visualization and analysis. They also enable building of dat ...

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Linking connectivity of deep brain stimulation of nucleus accumbens area with clinical depression improvements: a retrospective longitudinal case series

Dimitri Nestor Alice Van De Ville, Katrin Petermann, Thuy Anh Khoa Nguyen, Maria Giulia Preti, Simona Leserri

Treatment-resistant depression is a severe form of major depressive disorder and deep brain stimulation is currently an investigational treatment. The stimulation's therapeutic effect may be explained through the functional and structural connectivities be ...

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A theory of memory consolidation and synaptic pruning in cortical circuits

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Over the course of a lifetime, the human brain acquires an astonishing amount of semantic knowledge and autobiographical memories, often with an imprinting strong enough to allow detailed information to be recalled many years after the initial learning exp ...

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Cortical cell assemblies and their underlying connectivity: an in silico study

Michael Reimann, András Ecker, Daniela Egas Santander, Sirio Bolaños Puchet, James Bryden Isbister

Recent developments in experimental techniques have enabled simultaneous recordings from thousands of neurons, enabling the study of functional cell assemblies. However, determining the patterns of synaptic connectivity giving rise to these assemblies rema ...

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Brain's Dynamic Functional Organization with Simultaneous EEG-fMRI Networks

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The brain's functional networks can be assessed using imaging techniques like functional magnetic resonance imaging (fMRI) and electroencephalography (EEG). Recent studies have suggested a link between the dynamic functional connectivity (dFC) captured by ...

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Functional neuroimaging options for tinnitus

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Background: The pathophysiology behind tinnitus is still not well understood. Different imaging methods help in the understanding of the complex relationships that lead to the perception of tinnitus.Objective: Herein, different functional imaging methods t ...

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Christoph Pokorny

Elvis Boci

Cortical dynamics underlie many cognitive processes and emerge from complex multi-scale interactions, which are challenging to study in vivo. Large-scale, biophysically detailed models offer a tool which can complement laboratory approaches. We present a m ...

2024