Publications associées à Distinct Activity Profiles of Somatostatin-Expressing Interneurons in the Neocortex

Publications associées (7)

Of mice and men: Dendritic architecture differentiates human from mouse neuronal networks

Henry Markram, Kathryn Hess Bellwald, Rodrigo de Campos Perin, Lida Kanari, Alexis Arnaudon, Ying Shi, Julie Meystre, Maurizio Ferdinando Pezzoli, Natali Barros Zulaica

The organizational principles that distinguish the human brain from other species have been a long-standing enigma in neuroscience. Focusing on the uniquely evolved human cortical layers 2 and 3, we computationally reconstruct the cortical architecture for ...

2025

Mechanistic Understanding of Neurobehavioral Effects of Insecticides on the Larvae of Zebrafish (Danio rerio)

Sarah-Katharina Könemann

Due to conservation of neuronal functioning across phyla, molecular targets of insecticides are similar in insects and vertebrates. Insecticides thus pose a risk to aquatic vertebrates, such as fish, and potentially cause neurotoxic effects. Although these ...

EPFL2022

LTP of inhibition at PV interneuron output synapses requires developmental BMP signaling

Ralf Schneggenburger, Denys Osypenko, Christopher Clark, Evan Dean Vickers

Parvalbumin (PV)-expressing interneurons (PV-INs) mediate well-timed inhibition of cortical principal neurons, and plasticity of these interneurons is involved in map remodeling of primary sensory cortices during critical periods of development. To assess ...

Nature Research2020

Optical sensory and motor mapping of mouse dorsal cortex

Matthieu Pierre Auffret

Throughout species, including mice and humans, we all have to make decisions to fulfill our fundamentals needs: eat, drink, explore, communicate, reproduce... To make those decisions, we have to collect informations from the surrounding world and to proces ...

EPFL2018

Engineering Neuron Models : from Ion Channels to Electrical Behavior

Rajnish Ranjan

The neocortex is one of the most evolved and complex region of the brain. For more than a century scientists have been curious about the neocortex, to identify the anatomical blueprint of its cellular organization and to understand its role in higher brain ...

EPFL2011

Cell loss in the motor and cingulate cortex correlates with symptomatology in Huntington's disease

Huntington's disease is an autosomal dominant inherited neurodegenerative disease with motor symptoms that are variably co-expressed with mood and cognitive symptoms, and in which variable neuronal degeneration is also observed in the basal ganglia and the ...

Oxford University Press2010

The neocortical microcircuit as a tabula rasa

Henry Markram, Gilad Silberberg

The neocortex has a high capacity for plasticity. To understand the full scope of this capacity, it is essential to know how neurons choose particular partners to form synaptic connections. By using multineuron whole-cell recordings and confocal microscopy ...

National Academy of Sciences2005