Publications associées à From Surfactants to Viscoelastic Capsules

Selectively permeable microcapsules

Microcapsules are appealing containers for delivering active ingredients, such as drugs and cosmetics, or conducting chemical and biological reactions on a small scale. To control the timing and location of release of these encapsulants, the shells of micr ...

EPFL2023

Repurposed drug combination via high-throughput screening and dual drug delivery system development for the treatment of retinoblastoma

Po-Jen Tseng

The goal of retinoblastoma (RB) treatment is to save the child's life, eyes and functional vision, with that order of priority. The management of RB is complex and involves strategically chosen methods of surgical enucleation, external beam radiotherapy, i ...

EPFL2022

Fabrication of micrometer-sized drops as templates for particles

Mathias Steinacher

Drops are omnipresent in our daily life for example in the form of rain drops or as oil drops in a salad dressing. On a technological basis, drops can be used to conduct chemical or biological reactions. These drops often serve as templates to produce mate ...

EPFL2021

A Strategy to Conjugate Bioactive Fragments to Cytotoxic Diiron Bis(cyclopentadienyl) Complexes

Paul Joseph Dyson, Mouna Hadiji, Silvia Schoch, Sarah Alexandra Pais Pereira

A series of bioactive molecules were synthesized from the condensation of aspirin or chlorambucil with terminal alkynes bearing alcohol or amine substituents. Insertion of the resulting alkynes into the iron-carbyne bond of readily accessible diiron bis(cy ...

AMER CHEMICAL SOC2021

Wireless soft microscale actuators and robotic devices to study mechanobiology

Raquel Filipa Penacho Parreira

Tissues morphogenesis and homeostasis involve the spatiotemporal regulation of mechanics at multiple scales. Characterization of mechanical properties of biological systems as well as investigating the effects of mechanical forces on biological function ar ...

EPFL2021

5-Fluorouracil Release from Chitosan-Based Matrix. Experimental and Theoretical Aspects

Maria-Alexandra Paun

A series of four drug release formulations based on 5-fluorouracil encapsulated into a chitosan-based matrix were prepared by in situ hydrogelation with 3,7-dimethyl-2,6-octadienal. The formulations were investigated from structural and morphological aspec ...

2020

Released Diclofenac Sodium Salt From Chitosan Embedding In A Hydrogel Matrix. A Theoretical And Experimental Study

Maria-Alexandra Paun

Two formulations embedding diclofenac sodium salt into a chitosan hydrogel matrix with different crosslinking degree were prepared by in situ hydrogelation. The formulations were investigated by polarized light microscopy and scanning electron microscopy, ...

UNIV POLITEHNICA BUCHAREST, SCI BULL2020

Mechano-responsive microcapsules with uniform thin shells

Esther Amstad, Antoine Claude Jean Vian

Capsules often prolong the shelf-life of active ingredients, such as many types of drugs, food additives, or cosmetic substances, because they delay oxidation of these substances or prevent their reactions with molecules contained in the surrounding. If ca ...

2019

Bioinspired Viscoelastic Capsules: Delivery Vehicles and Beyond

Esther Amstad, Gianluca Nicolas Etienne, Irvine Lian Hao Ong

Microcapsules are often used as individually dispersed carriers of active ingredients to prolong their shelf life or to protect premature reactions with substances contained in the surrounding. This study goes beyond this application and employs microcapsu ...

Wiley2019

Capsules with submicron shells: production, stability, and leakage behavior

Antoine Claude Jean Vian

Capsules are often employed to prolong the shelf-life of active ingredients such as many drugs, food additives, or cosmetic substances because they delay their oxidation or prevent interactions with molecules contained in the surrounding. If designed prope ...

EPFL2018

Comparative Results From a National Joint Registry Hip Data Set of a New Cross-Linked Annealed Polyethylene vs Both Conventional Polyethylene and Ceramic Bearings

Brigitte Jolles-Haeberli

Background: Major concerns in hip arthroplasty concern the fate of bearing surfaces. Highly cross-linked polyethylene materials (HXLPE) currently demonstrate successful in vitro results with new technical procedures of cross-linking the polyethylene materi ...

2016

Design, development, and validation of an in-situ biosensor array for metabolite monitoring of cell cultures

Marco Mazza, Giovanni De Micheli, Cristina Boero, Sandro Carrara, Jacopo Olivo, Maria Antonietta Casulli, Lorenzo Foglia

Conventional pharmaceutical processes involving cell culture growth are generally taken under control with expensive and long laboratory tests performed by direct sampling to evaluate quality. This traditional and well-established approach is just partiall ...

Elsevier2014

Alginate-Poly(ethylene glycol) Hybrid Microspheres for Primary Cell Microencapsulation

Jutta Christine Wandrey, Redouan Mahou

The progress of medical therapies, which rely on the transplantation of microencapsulated living cells, depends on the quality of the encapsulating material. Such material has to be biocompatible, and the microencapsulation process must be simple and not h ...

Mdpi Ag2014

Photopatterning of Synthetic Hydrogels

Katarzyna Mosiewicz

In recent years sophisticated biomaterials have made a significant impact on our understanding of cellular behavior, particularly in the fields of stem cell research and tissue engineering. Nevertheless, the promising potential of stem cells for regenerati ...

EPFL2012

UV-cured Epoxy for Adhesion in Steel Reinforced Thermoplastic Composites

Basile Golaz

This work addresses the development of composite materials that contain metallic load-bearing cords with the aim of combining outstanding mechanical performance with added functionality, including electrical conductivity, data transmission, and temperature ...

EPFL2012

Highly Sensitive Carbon Nanotube-Based Sensing for Lactate and Glucose Monitoring in Cell Culture

Giovanni De Micheli, Cristina Boero, Sandro Carrara, Giovanna Del Vecchio

Monitoring of metabolic compounds in cell cultures can provide real-time information of cell line status. This is particularly important in those lines not fully known, as the case of embryonic and mesenchymal cells. On the other hand, such approach can pa ...

Institute of Electrical and Electronics Engineers2011

Dark curing kinetics of UV printing inks by real-time ATR-FTIR spectroscopy

Eric Jacques Nouzille

In UV-curable printing technology, an ink or a varnish is exposed to the UV-light source within a fraction of a second. Subsequent polymerization therefore proceeds in the dark, referred to as dark curing. Because dark curing can be critical and contribute ...

EPFL2007

Development of a novel drug delivery system based on polymeric, thermoresponsive, hydrogel nanoparticles

Carrier-mediated drug delivery has emerged as a powerful methodology for the treatment of various pathologies. The therapeutic index of traditional and novel drugs is enhanced via the increase of specificity due to targeting of drugs to a particular tissue ...

EPFL2005