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Measuring compartmental T-2-orientational dependence in human brain white matter using a tiltable RF coil and diffusion-T-2 correlation MRI

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Publications associées (36)

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Voxel-Wise Brain Graphs From Diffusion MRI: Intrinsic Eigenspace Dimensionality and Application to Functional MRI

Anjali Bagunu Tarun, Hamid Behjat

Goal: Structural brain graphs are conventionally limited to defining nodes as gray matter regions from an atlas, with edges reflecting the density of axonal projections between pairs of nodes. Here we explicitly model the entire set of voxels within a brai ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2025

Individually optimized dynamic parallel transmit pulses for 3D high‐resolution SPACE imaging at 7T

Emilie Claire Sleight, Natalia Pato Montemayor, Bénédicte Marie Maréchal, Tom Hilbert, Thomas Yu, Tommaso Di Noto, Jocelyn Philippe, Lina Bacha

Purpose: Although clinical 7T MRI offers various advantages compared to lower field strengths, achieving spatially uniform flip angle distributions remains a challenge. Sampling Perfection with Application optimized Contrast using different flip angle Evol ...

Wiley2025

White adipose tissue distribution and amount are associated with increased white matter connectivity

Jean-Philippe Thiran, Gabriel Girard, Elda Fischi Gomez, Philipp Johannes Koch

Obesity represents a significant public health concern and is linked to various comorbidities and cognitive impairments. Previous research indicates that elevated body mass index (BMI) is associated with structural changes in white matter (WM). However, a ...

Wiley2024

Multiparametric Characterization and Spatial Distribution of Different MS Lesion Phenotypes

Tobias Kober, Tom Hilbert, Gian Franco Piredda

BACKGROUND AND PURPOSE: MS lesions exhibit varying degrees of axonal and myelin damage. A comprehensive description of lesion phenotypes could contribute to an improved radiologic evaluation of smoldering inflammation and remyelination processes. This stud ...

Amer Soc Neuroradiology2024

Diffusion of brain metabolites highlights altered brain microstructure in type C hepatic encephalopathy: a 9.4 T preliminary study

Cristina Ramona Cudalbu Moldovan, Dunja Simicic, Katarzyna Pierzchala, Jessie Julie Mosso, Guillaume Miro André Briand

Introduction Type C hepatic encephalopathy (HE) is a decompensating event of chronic liver disease leading to severe motor and cognitive impairment. The progression of type C HE is associated with changes in brain metabolite concentrations measured by 1H m ...

Frontiers Media Sa2024

Molecular intercalation in the van der Waals antiferromagnets FePS3 and NiPS3

Bruce Normand

We have performed electrochemical treatment of the van der Waals antiferromagnetic materials FePS3 and NiPS3 with the ionic liquid EMIM-BF4, achieving significant molecular intercalation. Mass analysis of the intercalated compounds, EMIMx-FePS3 and EMIMx-N ...

Amer Physical Soc2024

Development and clinical validation of computational imaging biomarkers for neurodegenerative diseases

Veronica Lily Ravano

Neurodegenerative and neuroinflammatory disorders often involve complex pathophysiological mechanisms that are â to this date â only partially understood. A more comprehensive understanding of those microstructural processes and their characterization ...

EPFL2024

Parental status and markers of brain and cellular age: A 3D convolutional network and classification study

Donal Patrick Hill

Recent research shows prominent effects of pregnancy and the parenthood transition on structural brain characteristics in humans. Here, we present a comprehensive study of how parental status and number of children born/fathered links to markers of brain a ...

Pergamon-Elsevier Science Ltd2024

Magnetostriction-Driven Muon Localization in an Antiferromagnetic Oxide

Nicola Marzari, Iurii Timrov, Lorenzo Monacelli

Magnetostriction results from the coupling between magnetic and elastic degrees of freedom. Though it is associated with a relatively small energy, we show that it plays an important role in determining the site of an implanted muon, so that the energetica ...

Amer Physical Soc2024

Pore size estimation in axon-mimicking microfibers with diffusion-relaxation MRI

Jean-Philippe Thiran, Erick Jorge Canales Rodriguez, Muhamed Barakovic, Marco Pizzolato

Purpose: This study aims to evaluate two distinct approaches for fiber radius estimation using diffusion-relaxation MRI data acquired in biomimetic microfiber phantoms that mimic hollow axons. The methods considered are the spherical mean power-law approac ...

Wiley2024

Longitudinal Analysis of Brain Function-Structure Dependencies in 22q11.2 Deletion Syndrome and Psychotic Symptoms

Dimitri Nestor Alice Van De Ville, Maria Giulia Preti

Background: Compared with conventional unimodal analysis, understanding how brain function and structure relate to one another opens a new biologically relevant assessment of neural mechanisms. However, how function-structure dependencies (FSDs) evolve thr ...

2024

Noise-reduction techniques for 1H-FID-MRSI at 14.1 T: Monte Carlo validation and in vivo application

Cristina Ramona Cudalbu Moldovan, Bernard Lanz, Dunja Simicic, Jessie Julie Mosso, Thanh Phong Kevin Lê, Guillaume Miro André Briand, Brayan Alves

Proton magnetic resonance spectroscopic imaging (1H-MRSI) is a powerful tool that enables the multidimensional non-invasive mapping of the neurochemical profile at high resolution over the entire brain. The constant demand for higher spatial resolution in ...

Wiley2024

The interplay between white adipose tissue, adipokines, and structural gray matter changes

Jean-Philippe Thiran, Gabriel Girard, Elda Fischi Gomez

The growing global obesity issue emphasizes the importance of understanding its health implications. Previous research has identified consistent alterations in gray matter (GM) volume in connection with obesity. Given the various implications of distinct f ...

Wiley2024

Re-design of EU DEMO with a low aspect ratio

Xabier Sarasola Martin

The design point that had been chosen for EU DEMO in 2016 is reviewed here and a modification is proposed with a lower aspect ratio. Previously the same aspect ratio, A, was chosen for EU DEMO as in major tokamak experiments including ITER (A = 3.1), and, ...

Elsevier2024

Anomalous‐Chern Steering of Topological Nonreciprocal Guided Waves

Romain Christophe Rémy Fleury, Haoye Qin, Zhe Zhang, Qiaolu Chen, Zhechen Zhang

Nonreciprocal topological edge states based on external magnetic bias have been regarded as the last resort for genuine unidirectional wave transport, showing superior robustness over topological states with preserved time-reversal symmetry. However, fast ...

Wiley2024

New insights into rodent brain microstructure and metabolism in hepatic encephalopathy

Jessie Julie Mosso

Type C hepatic encephalopathy (HE) is a severe neuropsychiatric complication of chronic liver disease, for which the prognosis is poor in the absence of liver transplantation. Cirrhosis in type C HE leads to a toxic accumulation of ammonia in the blood, wh ...

EPFL2023

Neurobiological and metabolic basis of motivation and effort-based decision-making - A human 1H-MRS, fMRI and machine learning study

Arthur Barakat

Motivation is a multifaceted phenomenon that we explore within the framework of decision-making. Through this cognitive process, actions are directed towards specific goals by performing a trade-off between the cost and benefit of an action. The dorsomedia ...

EPFL2024

Magnetic structure and magnetoelectric properties of the spin-flop phase in LiFePO4

Paola Caterina Forino, Ellen Fogh, Sofie Janas

We investigate the magnetic structure and magnetoelectric(ME) effect in the high -field phase of the antiferromagnet LiFePO 4 above the critical field of 31 T. A neutron diffraction study in pulsed magnetic fields reveals the propagation vector to be q = 0 ...

Amer Physical Soc2024

Axial and radial axonal diffusivities and radii from single encoding strongly diffusion-weighted MRI

Erick Jorge Canales Rodriguez, Marco Pizzolato

We enable the estimation of the per-axon axial diffusivity from single encoding, strongly diffusion-weighted, pulsed gradient spin echo data. Additionally, we improve the estimation of the per-axon radial diffusivity compared to estimates based on spherica ...

ELSEVIER2023

Brain microstructural and functional MRI: developments and application to a rat model of Alzheimer's disease

Yujian Diao

Magnetic resonance imaging (MRI) has been a valuable tool in investigating the pathological cascade of Alzheimer's disease (AD) and its progression, which are still open questions. Although some MRI-derived hallmarks in terms of functional connectivity and ...

EPFL2023