Publications associées à Growth of Secondary Dendrite Arms of Fe C Alloy during Transient Directional Solidification by Phase-field Method

Axonal projections from mouse whisker-related sensory cortex

Neurons primarily communicate through release of neurotransmitter from presynaptic specialisations along their axonal arborisations. In order to understand the functional role of a specific neuron, it is therefore of great interest to know the structure of ...

EPFL2023

Cortical cell assemblies and their underlying connectivity: an in silico study

Michael Reimann, András Ecker, Daniela Egas Santander, Sirio Bolaños Puchet, James Bryden Isbister

Recent developments in experimental techniques have enabled simultaneous recordings from thousands of neurons, enabling the study of functional cell assemblies. However, determining the patterns of synaptic connectivity giving rise to these assemblies rema ...

2024

Photocured Nanocellulose Composites: Recent Advances

Yves Leterrier, Aigoul Schreier, Mohammed Arif Poothanari, Julien Bras

This perspective gives an overview of recent progress in thefield of photocured polymer composites based on variousforms of nanocelluloses, with a focus on cellulose nanofibrils. The manufacturing processes and performances of these nanocellulosecomposites ...

AMER CHEMICAL SOC2022

The Neuron Phenotype Ontology: A FAIR Approach to Proposing and Classifying Neuronal Types

Sean Lewis Hill, Mohameth François Sy

The challenge of defining and cataloging the building blocks of the brain requires a standardized approach to naming neurons and organizing knowledge about their properties. The US Brain Initiative Cell Census Network, Human Cell Atlas, Blue Brain Project, ...

HUMANA PRESS INC2022

Improved Cell-Free Transcription-Translation Reactions in Microfluidic Chemostats Augmented with Hydrogel Membranes for Continuous Small Molecule Dialysis

Sebastian Maerkl, Barbora Lavickova, Laura Sophie Grasemann

Increasing the protein production capacity of the PURE cell-free transcription-translation (TX-TL) system will be key to implementing complex synthetic biological circuits, and to establishing a fully self-regenerating system as a basis for the development ...

AMER CHEMICAL SOC2022

Axonal and Dendritic Morphology of Excitatory Neurons in Layer 2/3 Mouse Barrel Cortex Imaged Through Whole-Brain Two-Photon Tomography and Registered to a Digital Brain Atlas

Carl Petersen, Sylvain Crochet, Georgios Foustoukos, Yanqi Liu

Communication between cortical areas contributes importantly to sensory perception and cognition. On the millisecond time scale, information is signaled from one brain area to another by action potentials propagating across long-range axonal arborizations. ...

FRONTIERS MEDIA SA2022

Does powder averaging remove dispersion bias in diffusion MRI diameter estimates within real 3D axonal architectures?

Marco Pizzolato, Tim Bjørn Dyrby

Noninvasive estimation of axon diameter with diffusion MRI holds the potential to investigate the dynamic properties of the brain network and pathology of neurodegenerative diseases. Recent studies use powder averaging to account for complex white matter a ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2022

High synaptic threshold for dendritic NMDA spike generation in human layer 2/3 pyramidal neurons

James Gonzalo King, Suraj Honnuraiah

Neurons receive synaptic input primarily onto their dendrites. While we know much about the electrical properties of dendrites in rodents, we have only just started to describe their properties in the human brain. Here, we investigate the capacity of human ...

2022

HippoUnit: A software tool for the automated testing and systematic comparison of detailed models of hippocampal neurons based on electrophysiological data

Eilif Benjamin Muller, Werner Alfons Hilda Van Geit, Armando Romani, Szabolcs Kali, Sàra Sàray, Carmen Alina Lupascu, Rosanna Migliore, Luca Leonardo Bologna, Shailesh Appukuttan

Anatomically and biophysically detailed data-driven neuronal models have become widely used tools for understanding and predicting the behavior and function of neurons. Due to the increasing availability of experimental data from anatomical and electrophys ...

2021

Unpacking the Green Economy concept: A quantitative analysis of 140 definitions

Romano Tobias Wyss, Albert Merino, Marta Giulia Baldi

Over the past ten years, the Green Economy (GE) concept has gained momentum in both academia and policy-making arenas, leading to international programs in diverse sectors and driving national agendas all over the world. The concept is however highly contr ...

2020

Structural and functional brain imaging using extended-focus optical coherence tomography and microscopy

Paul James Marchand

Neuroimaging techniques aim at revealing the anatomy and functional organisation of cerebral structures. Over the past decades, functional magnetic resonance imaging (fMRI) has revolutionized our understanding of human cerebral physiology through its abili ...

EPFL2018

Neuronal morphologies: the shapes of thoughts

Lida Kanari

The mammalian brain, one of the most fascinating systems in nature, is a complex biological structure that has kept scientists busy for over a century. Many of the brain's mysteries have been unraveled due to the enormous efforts of the scientific communit ...

EPFL2018

Comprehensive Morpho-Electrotonic Analysis Shows 2 Distinct Classes of L2 and L3 Pyramidal Neurons in Human Temporal Cortex

Idan Segev, Guy Antoine Atenekeng Kahou, Lida Kanari, Guy Eyal, Yair Deitcher

There have been few quantitative characterizations of the morphological, biophysical, and cable properties of neurons in the human neocortex. We employed feature-based statistical methods on a rare data set of 60 3D reconstructed pyramidal neurons from L2 ...

2017

Tuning growth direction of catalyst-free InAs(Sb) nanowires with indium droplets

Anna Fontcuberta i Morral, Gözde Tütüncüoglu, Martin George Friedl, Heidi Andrea Potts, Nicholas Paul Morgan

The need for indium droplets to initiate self-catalyzed growth of InAs nanowires has been highly debated in the last few years. Here, we report on the use of indium droplets to tune the growth direction of self-catalyzed InAs nanowires. The indium droplets ...

Institute of Physics2017

Influencing axon regeneration after spinal cord injury

Mark Andrew Anderson

Spinal cord injury (SCI) results in a severing of axonal connections that leads to permanent sensorimotor deficits. In cases of incomplete injury, rehabilitation paradigms have been reported to be successful in improving behavioral outcome in humans with S ...

EPFL2017

Effect of fiber orientation on the in-plane tensile response of UHPFRC reinforcement layers

Eugen Brühwiler, Emmanuel Denarié, Maléna Bastien Masse

The application on existing Reinforced Concrete (RC) slabs of cast-on site Ultra-High Performance Fiber Reinforced cement-based Composite UHPFRC) layers is a very efficient reinforcement technique, currently spreading. For the design of these tensile reinf ...

Elsevier2016

Framework for efficient synthesis of spatially embedded morphologies

Julian Charles Shillcock, Guy Antoine Atenekeng Kahou, Lida Kanari, Juan Pablo Palacios, Liesbeth Maria L Vanherpe

Many problems in science and engineering require the ability to grow tubular or polymeric structures up to large volume fractions within a bounded region of three-dimensional space. Examples range from the construction of fibrous materials and biological c ...

Amer Physical Soc2016

A Model Predictive Control scheme with Ultimate Bound for Economic Optimization

Colin Neil Jones, Andrea Alessandretti

This paper presents a Model Predictive Control (MPC) scheme for nonlinear continuous-time systems where an economic stage cost, which is not a measure of the distance to a desired set point, is combined with a classic stabilizing stage cost. The associated ...

2015

Controlling Mesopore Size and Processability of Transparent Enzyme-Loaded Silica Films for Biosensing Applications

Bernard Wenger, Heinrich Hofmann, Raphaël Pugin, Oswaldo Javier Pérez Anguiano, Emmanuel Scolan

Silica-based nanoporous thin films including large mesopores are relevant as enzyme supports for applications in biosensing. The diffusion and immobilization of large biomolecules such as enzymes in such porous films require the presence of large mesopores ...

Amer Chemical Soc2015

Influence of Zinc Anisotropy on Solidification Microstructures: Experimental Results and Phase-Field Simulations

Alexandre Durussel

Due to a distortion of its hexagonal unit cell along the c-axis compared to hexagonal-close-packed metals (c/a = 1.856 instead of 1.633), zinc is characterised by a large anisotropy of its solid-liquid interfacial energy. While previous studies have focuse ...

EPFL2015