Detection of Movement Related Cortical Potential: Effects of Causal vs. Non-Causal Processing

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Neurophysiological underpinnings of an intensive protocol for upper limb motor recovery in subacute and chronic stroke patients

Silvestro Micera

ABS T R A C T BACKGROUND: Upper limb (UL) motor impairment following stroke is a leading cause of functional limitations in activities of daily living. Robot-assisted therapy supports rehabilitation, but how its efficacy and the underlying neural mechanism ...

Edizioni Minerva Medica2023

Causal inference with recurrent and competing events

Mats Julius Stensrud, Pal Christie Ryalen, Matias Janvin

Many research questions concern treatment effects on outcomes that can recur several times in the same individual. For example, medical researchers are interested in treatment effects on hospitalizations in heart failure patients and sports injuries in ath ...

SPRINGER2023

Do we really measure what we think we are measuring?

Michael Herzog, Janir Nuno Ramos Antunes Da Cruz, Simona Adele Garobbio, Dario Alejandro Gordillo Lopez

Tests used in the empirical sciences are often (implicitly) assumed to be representative of a given research question in the sense that similar tests should lead to similar results. Here, we show that this assumption is not always valid. We illustrate our ...

Cell Press2023

CDKL5 sculpts functional callosal connectivity to promote cognitive flexibility

Valerio Zerbi

Functional and structural connectivity alterations in short- and long-range projections have been reported across neurodevelopmental disorders (NDD). Interhemispheric callosal projection neurons (CPN) represent one of the major long-range projections in th ...

SPRINGERNATURE2023

Inferring individual evaluation criteria for reaching trajectories with obstacle avoidance from EEG signals

José del Rocio Millán Ruiz, Aude Billard, Fumiaki Iwane

During reaching actions, the human central nerve system (CNS) generates the trajectories that optimize effort and time. When there is an obstacle in the path, we make sure that our arm passes the obstacle with a sufficient margin. This comfort margin varie ...

Nature Portfolio2023

Spectral representation of EEG data using learned graphs with application to motor imagery decoding

Maliheh Miri, Dimitri Nestor Alice Van De Ville, Hamid Behjat

Electroencephalography (EEG) data entail a complex spatiotemporal structure that reflects ongoing organi-zation of brain activity. Characterization of the spatial patterns is an indispensable step in numerous EEG processing pipelines. We present a novel me ...

Elsevier Sci Ltd2023

Interventionist estimands in event history analysis

Matias Janvin

The presence of competing events, such as death, makes it challenging to define causal effects on recurrent outcomes. In this thesis, I formalize causal inference for recurrent events, with and without competing events. I define several causal estimands an ...

EPFL2023

Deplatforming did not decrease Parler users' activity on fringe social media

Robert West, Manoel Horta Ribeiro

Online platforms have banned ("deplatformed") influencers, communities, and even entire websites to reduce content deemed harmful. Deplatformed users often migrate to alternative platforms, which raises concerns about the effectiveness of deplatforming. He ...

OXFORD UNIV PRESS2023

The arrow-of-time in neuroimaging time series identifies causal triggers of brain function

Dimitri Nestor Alice Van De Ville, Maria Giulia Preti, Thomas William Arthur Bolton, Enrico Amico, Raphaël Pierre Liégeois

Moving from association to causal analysis of neuroimaging data is crucial to advance our understanding of brain function. The arrow-of-time (AoT), that is, the known asymmetric nature of the passage of time, is the bedrock of causal structures shaping phy ...

Wiley2023

DISCO: Distilling Counterfactuals with Large Language Models

Antoine Bosselut, Zeming Chen

Models trained with counterfactually augmented data learn representations of the causal structure of tasks, enabling robust generalization. However, high-quality counterfactual data is scarce for most tasks and not easily generated at scale. When crowdsour ...

Assoc Computational Linguistics-Acl2023

Hardware Implementation of Digital Signal Processing Algorithms for Programmable Epilepsy Control Systems

Keyvan Farhang Razi

Epilepsy is a common chronic neurological disorder that causes recurring seizures and affects more than 50 million people worldwide. Implantable medical devices (IMDs) are regarded as effective tools to cure patients who suffer from refractory epilepsy. Se ...

EPFL2023

Brain's Dynamic Functional Organization with Simultaneous EEG-fMRI Networks

Patricia Figueiredo, João Pedro Forjaco Jorge

The brain's functional networks can be assessed using imaging techniques like functional magnetic resonance imaging (fMRI) and electroencephalography (EEG). Recent studies have suggested a link between the dynamic functional connectivity (dFC) captured by ...

SPRINGER INTERNATIONAL PUBLISHING AG2023