Publication

Upstream binding protein 1 polymorphisms and their use for prognosing or diagnosing arterial blood pressure

Johan Auwerx
2011
Patents

Résumé

The present invention is directed to methods for diagnosis and prognosis using polymorphic variants of Ubp 1 s and related probes and kits.

Source officielle

https://infoscience.epfl.ch/entities/publication/4893c580-7f42-4747-bde3-fc27fedf39d1

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Johan Auwerx
2011
Patents

Résumé

The present invention is directed to methods for diagnosis and prognosis using polymorphic variants of Ubp 1 s and related probes and kits.

Source officielle

https://infoscience.epfl.ch/entities/publication/4893c580-7f42-4747-bde3-fc27fedf39d1

À propos de ce résultat

Concepts associés (8)

Blood pressure

Blood pressure (BP) is the pressure of circulating blood against the walls of blood vessels. Most of this pressure results from the heart pumping blood through the circulatory system. When used without qualification, the term "blood pressure" refers to the pressure in a brachial artery, where it is most commonly measured. Blood pressure is usually expressed in terms of the systolic pressure (maximum pressure during one heartbeat) over diastolic pressure (minimum pressure between two heartbeats) in the cardiac cycle.

Blood pressure measurement

Arterial blood pressure is most commonly measured via a sphygmomanometer, which historically used the height of a column of mercury to reflect the circulating pressure. Blood pressure values are generally reported in millimetres of mercury (mmHg), though aneroid and electronic devices do not contain mercury. For each heartbeat, blood pressure varies between systolic and diastolic pressures. Systolic pressure is peak pressure in the arteries, which occurs near the end of the cardiac cycle when the ventricles are contracting.

Hypertension artérielle

L’hypertension artérielle (HTA) persistante est une pathologie cardiovasculaire définie par une pression artérielle trop élevée. Souvent multifactorielle, l'HTA peut être aiguë ou chronique, avec ou sans signes de gravité. On parle communément d'hypertension artérielle pour une pression artérielle systolique supérieure à et une pression artérielle diastolique supérieure à . La pression artérielle doit être mesurée plus d'une fois, en position assise ou allongée, après de repos.

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Central aortic diastolic pressure decay time constant ( ) is according to the two-element Windkessel model equal to the product of total peripheral resistance (R) times total arterial compliance (C ). As such, it is related to arterial stiffness, which has ...

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Arterial pulse wave modeling and analysis for vascular-age studies: a review from VascAgeNet

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Arterial pulse waves (PWs) such as blood pressure and photoplethysmogram (PPG) signals contain a wealth of information on the cardiovascular (CV) system that can be exploited to assess vascular age and identify individuals at elevated CV risk. We review th ...

AMER PHYSIOLOGICAL SOC2023

Modulation of Pulsatile Left Ventricular Afterload by Renal Denervation in Heart Failure With Preserved Ejection Fraction

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Background:Arterial stiffening contributes to hemodynamic derangements in heart failure with preserved ejection fraction (HFpEF). We sought to investigate the impact of renal denervation on pulsatile left ventricular loading in patients with HFpEF and hype ...

Lippincott Williams & Wilkins2023

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