Temperature Dependence of Normal Mode Reconstructions of Protein Dynamics

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In this paper, we quantify weak protein-protein interactions in solution using cross-interaction chromatography (CIC) and surface plasmon resonance (SPR) and demonstrate that they can be modulated by the addition of millimolar concentrations of free amino ...

Geomembrane systems have been used at hydropower plants as rehabilitation and mitigation technology for several decades and are now used worldwide. In the context of planning an energy transition that promotes the sustainable use of water resources for ene ...

In this paper we will consider distributed Linear-Quadratic Optimal Control Problems dealing with Advection-Diffusion PDEs for high values of the Peclet number. In this situation, computational instabilities occur, both for steady and unsteady cases. A Str ...

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The synthesis of complex sugars is a key aspect of microbial biology. Cyclic beta-1,2-glucan (C beta G) is a circular polysaccharide critical for host interactions of many bacteria, including major pathogens of humans (Brucella) and plants (Agrobacterium). ...

Molecular quantum dynamics simulations are essential for understanding many fundamental phenomena in physics and chemistry. They often require solving the time-dependent Schrödinger equation for molecular nuclei, which is challenging even for medium-sized ...

A sample of 3984 candidates of the K+ -> pi(+)gamma gamma decay, with an estimated background of 291 +/- 14 events, was collected by the NA62 experiment at CERN during 2017-2018. In order to describe the observed di-photon mass spectrum, the next-to-leadin ...

The probability of detecting technosignatures (i.e., evidence of technological activity beyond Earth) increases with their longevity, or the time interval over which they manifest. Therefore, the assumed distribution of longevities has some bearing on the ...

Under resource constraints, LLMs are usually fine- tuned with additional knowledge using Parameter Efficient Fine-Tuning (PEFT), using Low-Rank Adaptation (LoRA) modules. In fact, LoRA injects a new set of small trainable matrices to adapt an LLM to a new ...

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Under resource constraints, LLMs are usually fine-tuned with additional knowledge using Parameter Efficient Fine-Tuning (PEFT), using Low-Rank Adaptation (LoRA) modules. In fact, LoRA injects a new set of small trainable matrices to adapt an LLM to a new t ...

Large language models (LLMs) have shown strong performance in tasks across domains but struggle with chemistry-related problems. These models also lack access to external knowledge sources, limiting their usefulness in scientific applications. We introduce ...

The application of computational biology in drug development for membrane protein targets has experienced a boost from recent developments in deep learning-driven structure prediction, increased speed and resolution of structure elucidation, machine learni ...

Temperature Dependence of Normal Mode Reconstructions of Protein Dynamics

Chattez avec Graph Search

Modulating Weak Protein-Protein Cross-Interactions by the Addition of Free Amino Acids at Millimolar Concentrations

A comprehensive review on geomembrane systems application in hydropower

A Streamline Upwind Petrov-Galerkin Reduced Order Method for Advection-Dominated Partial Differential Equations Under Optimal Control

Quartiers rhodaniens en transition

Machine Learning for Modeling Stock Returns

Structure-function analysis of the cyclic β-1,2-glucan synthase from Agrobacterium tumefaciens

High-order geometric integrators for the variational Gaussian wavepacket dynamics and application to vibronic spectra at finite temperature

Measurement of the K+ → π+γγ decay

Technosignatures Longevity and Lindy's Law

Beyond fine-tuning: LoRA modules boost near-OOD detection and LLM security

Bioengineering functional organoid models across scales

Beyond fine-tuning: LoRA modules boost near-OOD detection and LLM security

Augmenting large language models with chemistry tools

Computational drug development for membrane protein targets