Protocol for the PreventIT feasibility randomised controlled trial of a lifestyle-integrated exercise intervention in young older adults

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As the world’s population grows in cities, urban dwellers spend a large amount of time inside their home, making housing health ever more important. Critical for residents’ health, the interactions between indoor residential environments and outdoor enviro ...

Sedentary lifestyle is currently considered a global pandemic, associated with major health problems such as cardiovascular disease and premature death. Regular physical activity (PA) is one way to address this problem, as it brings a variety of health ben ...

The terminology of neurological disorders encompasses a range of serious illnesses (e.g., epilepsy, Alzheimer's disease) leading to morbidity, disability, and stigma. Epilepsy alone affects over 50 million people worldwide, and these figures are rising as ...

Tissue wounds are a significant challenge for the healthcare system, affecting millions globally. Current methods like suturing and stapling have limitations as they inadequately cover the wound, fail to prevent fluid leakage, and increase the risk of infe ...

Owing to stochastic fluctuations arising from finite population size, known as genetic drift, the ability of a population to explore a rugged fitness landscape depends on its size. In the weak mutation regime, while the mean steady-state fitness increases ...

Background Few studies have examined the interactions between individual socioeconomic position and neighbourhood deprivation and the findings so far are heterogeneous. Using a large sample of diverse cohorts, we investigated the interaction effect of neig ...

This article unites different disciplinary debates on ‘southern innovation’, ‘theory from the South’, and ‘decolonisation of knowledge’ in order to discuss existing understandings around the role of Africa in the production of health-related knowledge, pub ...

Age-related muscle dysfunction and sarcopenia are major causes of physical incapacitation in older adults and currently lack viable treatment strategies. Here we find that sphingolipids accumulate in mouse skeletal muscle upon aging and that both genetic a ...

Important brainstem regions are involved in the regulation of rapid eye movement sleep. We hypothesized that brainstem stroke is associated with dysregulated rapid eye movement sleep and related muscle activity. We compared quantitative/qualitative polysom ...

The largest source of systematic errors in the time-delay cosmography method likely arises from the lens model mass distribution, where an inaccurate choice of model could in principle bias the value of H-0. A Bayesian hierarchical framework has been propo ...

We present the La Mobiliere insurance customers dataset: a 12-year-long longitudinal collection of data on policies of customers of the Swiss insurance company La Mobiliere. To preserve the privacy of La Mobiliere customers, we propose the data aggregated ...

Smartphones present many interesting opportunities for survey research, particularly through the use of mobile data collection applications (apps). There is still much to learn, however, about how to integrate apps in general population surveys. Recent stu ...

Muscle stem cells (MuSCs) are the primary source of myogenic progenitors during muscle repair and are essential for the long-term regenerative capacity of skeletal muscle. Following myofiber injury, MuSCs transition from a quiescent to an activated state, ...

Objective This study explored the impact of time-restricted eating (TRE) versus standard dietary advice (SDA) on bone health. Methods Adults with >= 1 component of metabolic syndrome were randomized to TRE (ad libitum eating within 12 hours) or SDA (food p ...

The development of sustainable urban projects is crucial to address the challenges of the growing population living in cities. Facing complex decision-making and increasing expectations from inhabitants, local institutions are gradually becoming open to co ...

Urolithin A (UA) is a natural compound produced by gut bacteria from ingested ellagitannins (ETs) and ellagic acid (EA), complex polyphenols abundant in foods such as pomegranate, berries, and nuts. UA was discovered 40 years ago, but only recently has its ...

Real-time measure of muscular fatigue during physical exercise is highly demanded in fields as rehabilitation and physiotherapy, both hospital and home-based. In addition to the well-accepted features extracted from EMG measurements, an increasing interest ...

Personalizing behavior change (BC) strategies to motivate increased physical activity is especially important for the diverse older adult population. However, there is a lack of knowledge about how to profile older users to most effectively personalize BC ...

Demographic models of human cultural evolution have high explanatory potential but weak empirical support. Here we use a global dataset of rock art sites and climate and genetics-based estimates of ancient population densities to test a new model based on ...

Sustained ryanodine receptor (RyR) Ca2+ leak is associated with pathological conditions such as heart failure or skeletal muscle weakness. We report that a single session of sprint interval training (SIT), but not of moderate intensity continuous training ...

Protocol for the PreventIT feasibility randomised controlled trial of a lifestyle-integrated exercise intervention in young older adults

Chattez avec Graph Search

Housing, street and health: a new systemic research framework

Real world multimodal assessment of physical behavior change in health and disease

Real-time Personalized Monitoring of Neurological Disorders on Wearable Systems

Enhancing Robustness of Adhesive Hydrogels through PEG-NHS Incorporation

Impact of population size on early adaptation in rugged fitness landscapes

Association of neighbourhood disadvantage and individual socioeconomic position with all-cause mortality: a longitudinal multicohort analysis

Examining African contributions to global health: Reflections on knowledge circulation and innovation

Sphingolipids accumulate in aged muscle, and their reduction counteracts sarcopenia

REM sleep and muscle atonia in brainstem stroke: A quantitative polysomnographic and lesion analysis study

TOCOSMO VIII. A key test of systematics in the hierarchical method of time-delay cosmography

High spatial resolution dataset of La Mobiliere insurance customers

Data Privacy Concerns as a Source of Resistance to Complete Mobile Data Collection Tasks Via a Smartphone App

Molecular Regulation of Muscle Stem Cell Fate during Skeletal Muscle Regeneration and Aging

The effects of time-restricted eating and weight loss on bone metabolism and health: a 6-month randomized controlled trial

The Future of Civic Technologies for the Involvement of Citizens in Urban Planning: 3D Urban Participatory e-Planning in the Spotlight

Impact of the Natural Compound Urolithin A on Health, Disease, and Aging

Preliminary Study of a Flexible Printed Multi-Sensing Platform for Electromyography and Lactate Measuring during Rehabilitation

Identifying a Motivational Profile for Older Adults Towards Increased Physical Activity

Stabilization of cultural innovations depends on population density: Testing an epidemiological model of cultural evolution against a global dataset of rock art sites and climate-based estimates of ancient population densities

Acute RyR1 Ca2+ leak enhances NADH-linked mitochondrial respiratory capacity