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Publications associées (29)

The metalloprotease ADAMTS4 generates N-truncated A4-x species and marks oligodendrocytes as a source of amyloidogenic peptides in Alzheimer's disease

Patrick Fraering, Mitko Dimitrov, Hermeto Gerber, Sandra Lehmann

Brain accumulation and aggregation of amyloid- (A) peptides is a critical step in the pathogenesis of Alzheimer's disease (AD). Full-length A peptides (mainly A1-40 and A1-42) are produced through sequential proteolytic cleavage of the amyloid precursor pr ...

SPRINGER2019

Two-photon triggered photorelease of caged compounds from multifunctional harmonic nanoparticles

Sandrine Gerber, Luigi Bonacina, Daniel Ortiz Trujillo, Laure Menin, Raphaël Jovita De Matos, Jérémy Vuilleumier

The design of stimuli-responsive nanocarriers has raised much attention to achieve higher local concentration of therapeutics and mitigate the appearance of drug resistance. The combination of imaging properties and controlled photorelease of active molecu ...

2019

Effects of collisionality and T e /T i on fluctuations in positive and negative δ tokamak plasmas

Stephan Brunner, Ambrogio Fasoli, Olivier Sauter, Stefano Coda, Laurie Porte, Gabriele Merlo, Matteo Fontana, Ajay Chandrarajan Jayalekshmi

The effects of negative triangularity () on confinement and fluctuations in plasmas covering a large range of parameters were investigated on the tokamak à configuration variable (TCV). The conditions explored in this paper include discharges where neutral ...

IOP Publishing Ltd2019

Spatio-temporal structure of single neuron subthalamic activity identifies DBS target for anesthetized Tourette syndrome patients

Silvestro Micera, Matteo Vissani

Objective. Deep brain stimulation (DBS) of basal ganglia effectively tackles motor symptoms of movement disorders such as Tourette syndrome (TS). The precise location of target stimulation site determines the range of clinical outcome in DBS patients, and ...

IOP PUBLISHING LTD2019

The small RNA RyhB is a regulator of cytochrome expression in Shewanella oneidensis

Rizlan Bernier-Latmani, Karin Lederballe Meibom

Shewanella oneidensis produces an extensive electron transfer network that results in metabolic flexibility. A large number of c-type cytochromes are expressed by S. oneidensis and these function as the fundamental electron transport chain proteins. Althou ...

Frontiers Media SA2018

Mid-infrared frequency comb via coherent dispersive wave generation in silicon nitride nanophotonic waveguides

Tobias Kippenberg, Martin Hubert Peter Pfeiffer, Camille Sophie Brès, Adrien Billat, Hairun Guo, Davide Grassani, Clemens Herkommer, Chuankun Zhang, Wenle Weng

Mid-infrared optical frequency combs are of significant interest for molecular spectroscopy due to the large absorption of molecular vibrational modes on the one hand, and the ability to implement superior comb-based spectroscopic modalities with increased ...

Nature Publishing Group2018

Near-Optimal Noisy Group Testing via Separate Decoding of Items

Volkan Cevher, Jonathan Mark Scarlett

In this paper, we revisit an efficient algorithm for noisy group testing in which each item is decoded separately (Malyutov and Mateev, 1980), and develop novel performance guarantees via an information-theoretic framework for general noise models. For the ...

IEEE2018

Electron-Affinity-Triggered Variations on the Optical and Electrical Properties of Dye Molecules Enabling Highly Efficient Dye-Sensitized Solar Cells

Michael Graetzel, Shaik Mohammed Zakeeruddin, Péter Kalman Péchy, Ulf Anders Hagfeldt, Yiming Cao, Marko Stojanovic, Mohammad Ibrahim Dar, Yasemin Saygili, Weiwei Zhang, Yuhang Liu

The synthesis, characterization, and photovoltaic performance of a series of indacenodithiophene (IDT)-based D--A organic dyes with varying electron-accepting units is presented. By control of the electron affinity, perfectly matching energy levels were ac ...

Wiley-VCH Verlag GmbH2018

Near-Optimal Noisy Group Testing via Separate Decoding of Items

Volkan Cevher, Jonathan Mark Scarlett

The group testing problem consists of determining a small set of defective items from a larger set of items based on a number of tests, and is relevant in applications such as medical testing, communication protocols, pattern matching, and more. In this pa ...

2018

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