Publications associées à Infectious disease spread in connected communities

Publications associées (9)

Epidemicity conditions in spatial models of infectious diseases

We review the work that has been conducted in the past years to understand when and why significant epidemics may arise even though a disease is not bound to become endemic in the long run i.e. subthreshold outbreaks. In particular, we describe the methods ...

2025

Evolving Infectious Disease Dynamics Shape School-based Intervention Effectiveness

Sebastian Maerkl, Grégoire Michielin

School-based interventions during epidemics are often controversial, as experienced during the COVID-19 pandemic, where reducing transmission had to be weighed against the adverse effects on young children. However, it remains unclear how the broader epide ...

NATURE PORTFOLIO2025

Landscape and environmental heterogeneity support coexistence in competitive metacommunities

Andrea Rinaldo, Giorgio Nicoletti

Metapopulation models have been instrumental in quantifying the ecological impact of landscape structure on the survival of a focal species. However, extensions to multiple species with arbitrary dispersal networks often rely on phenomenological assumption ...

National Academy of Sciences2024

Sporadic type VI secretion in seventh pandemic Vibrio cholerae

Melanie Blokesch, Sandrine Stutzmann, Natalia Carolina Drebes Dorr, Nicolas René Chiaruttini, Loriane Bader, Sandrine Natacha Isaac, Lisa Christina Metzger, Alexis Joseph Proutière

Vibrio cholerae is a pathogen that causes disease in millions of people every year by colonizing the small intestine and then secreting the potent cholera toxin. How the pathogen overcomes the colonization barrier created by the host’s natural microbiota i ...

2023

Stay close, but not too close: aerial image analysis reveals patterns of social distancing in seal colonies

Devis Tuia, Benjamin Alexander Kellenberger

Many species aggregate in dense colonies. Species-specific spatial patterns provide clues about how colonies are shaped by various (a)biotic factors, including predation, temperature regulation or disease transmission. Using aerial imagery, we examined the ...

2023

In vitro synergistic action of TAT-RasGAP 317-326 peptide with antibiotics against Gram-negative pathogens

Grazia Vizzarro

Objectives: Multidrug-resistant (MDR) bacteria are a continuously increasing threat for medicine, caus-ing infections recalcitrant to antibiotics. Antimicrobial peptides (AMPs) were identified as alternatives to antibiotics, being naturally occurring short ...

2022

A Phylogeny-aware GWAS Framework to Correct for Heritable Pathogen Effects on Infectious Disease Traits

Jacques Fellay, Christian Axel Wandall Thorball

Infectious diseases are particularly challenging for genome-wide association studies (GWAS) because genetic effects from two organisms (pathogen and host) can influence a trait. Traditional GWAS assume individual samples are independent observations. Howev ...

OXFORD UNIV PRESS2022

Host genomics of SARS-CoV-2 infection

Jacques Fellay, Christian Axel Wandall Thorball

SARS-CoV-2 infected a large fraction of humans in the past 2 years. The clinical presentation of acute infection varies greatly between individuals, ranging from asymptomatic or mild to life-threatening COVID-19 pneumonia with multi-organ complications. De ...

SPRINGERNATURE2022

The epidemicity index of recurrent SARS-CoV-2 infections

Andrea Rinaldo

Several indices can predict the long-term fate of emerging infectious diseases and the effect of their containment measures, including a variety of reproduction numbers (e.g. R-0). Other indices evaluate the potential for transient increases of epidemics e ...

Nature Research2021