Publications associées à Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly

Publications associées (8)

Nfinder: automatic inference of cell neighborhood in 2D and 3D using nuclear markers

BackgroundIn tissues and organisms, the coordination of neighboring cells is essential to maintain their properties and functions. Therefore, knowing which cells are adjacent is crucial to understand biological processes that involve physical interactions ...

2023

Optical imaging of the small intestine immune compartment across scales

Aleksandra Radenovic, Olivier Burri, Arielle Louise Planchette, Alessio Mylonas

The limitations of 2D microscopy constrain our ability to observe and understand tissue-wide networks that are, by nature, 3-dimensional. Optical projection tomography (OPT) enables the acquisition of large volumes (ranging from micrometres to centimetres) ...

NATURE PORTFOLIO2023

Trans-anethole Induces Thermogenesis via Activating SERCA/SLN Axis in C2C12 Muscle Cells

Sulagna Mukherjee

Recently, adaptive non-shivering thermogenesis has attracted considerable attention because it can elevate energy expenditure and help treat obesity. Despite the numerous reports related to UCP1-driven thermogenesis, little is known regarding UCP1-independ ...

KOREAN SOC BIOTECHNOLOGY & BIOENGINEERING2022

Epidural electrical stimulation of the cervical dorsal roots restores voluntary upper limb control in paralyzed monkeys

Stéphanie Lacour, Grégoire Courtine, Jocelyne Bloch, Giuseppe Schiavone, Florian Dylan Fallegger, Quentin Barraud, Tomislav Milekovic, Katia Galan, Nicholas David James

Regaining arm control is a top priority for people with paralysis. Unfortunately, the complexity of the neural mechanisms underlying arm control has limited the effectiveness of neurotechnology approaches. Here, we exploited the neural function of survivin ...

NATURE PORTFOLIO2022

Impact of the Natural Compound Urolithin A on Health, Disease, and Aging

Johan Auwerx, Davide D'Amico, Pamela Solange Valdés Undurraga, Pénélope Andreux

Urolithin A (UA) is a natural compound produced by gut bacteria from ingested ellagitannins (ETs) and ellagic acid (EA), complex polyphenols abundant in foods such as pomegranate, berries, and nuts. UA was discovered 40 years ago, but only recently has its ...

2021

Co-regulation of endothelial and myogenic cell fates through intercellular crosstalk in skeletal muscle

Umji Lee

Skeletal muscle is one of the most dynamic organs in the human body, which has a vigorous potential to regenerate and adapt to environmental changes. Depending on environments, skeletal muscle enables essential life activities to survive by controlling mov ...

EPFL2021

Enhancing mitochondrial quality control to fight neuromuscular degeneration in aging and disease

Mario Romani

Loss of mitochondrial function and proteostasis typify aging and age-associated degenerative disorders such as Alzheimer's disease and muscle aging. To date, no cure or preventive measure is available to manage these conditions. Alterations of cellular pro ...

EPFL2021

Electro-Mechanical Coupling in Human Atrial Cardiomyocytes: Model Development and Analysis of Inotropic Interventions

Alfio Quarteroni

Human-based computational models are a powerful tool that complements the experimental approaches and can improve our understanding of individual components of the heart by integrating them into one system. This paper aims to couple and calibrate a human a ...

IEEE2021