ATLAS of Biochemistry: A Repository of All Possible Biochemical Reactions for Synthetic Biology and Metabolic Engineering Studies

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The outstanding information processing capacity of the brain relies on numerous molecular mechanisms. It is an extremely energy-expensive function, which involves specialization and collaboration of different cell types. A common framework to study the com ...

IntroductionDesulfitobacterium hafniense was isolated for its ability to use organohalogens as terminal electron acceptors via organohalide respiration (OHR). In contrast to obligate OHR bacteria, Desulfitobacterium spp. show a highly versatile energy meta ...

We propose a framework for the construction of 4D scientific models for cities of the past. It leverages both the use of computational methods for bootstrapping, and a collaborative interface for visualisation and edition. This permits to continuously enri ...

Physical interactions between proteins are essential for most biological processes governing life. However, the molecular determinants of such interactions have been challenging to understand, even as genomic, proteomic and structural data increase. This k ...

Background Innate immune cells play a crucial role in responding to microbial infections, but their improper activation can also drive inflammatory disease. For this reason, their activation state is governed by a multitude of factors, including the metabo ...

The notion that mitochondria cannot be lost was shattered with the report of an oxymonad Monocercomonoides exilis, the first eukaryote arguably without any mitochondrion. Yet, questions remain about whether this extends beyond the single species and how th ...

A method for optimizing memory access for database operations is provided. The method may include performing a first database operation by at least executing a first instruction stream associated with the first database operation. The first database opera ...

The AIDRES database aims to support the long-term objective of a fully integrated industrial strategy in the EU 27, providing a service to the European Commission and a catalogue for industries to understand the effectiveness, efficiency and cost of potent ...

Carbon dioxide generated by the human body and exhaled (VCO2) is commonly used for ventilation controls, while the metabolic rate (i.e., energy expenditure EE) is an important parameter defining human thermal comfort in buildings. These two parameters are ...

Neonatal hypoxic-ischemic (HI) encephalopathy (HIE) in term newborns is a leading cause of mortality and chronic disability. Hypothermia (HT) is the only clinically available therapeutic intervention; however, its neuroprotective effects are limited. Lacto ...

Disturbances in the brain's capacity to meet its energy demand increase the risk of synaptic loss, neurodegeneration, and cognitive decline. Nutritional and metabolic interventions that target metabolic pathways combined with diagnostics to identify defici ...

Analytical workloads are evolving as the number of users surges and applications that submit queries in batches become popular. However, traditional analytical databases that optimize-then-execute each query individually struggle to provide timely response ...

ATLAS of Biochemistry: A Repository of All Possible Biochemical Reactions for Synthetic Biology and Metabolic Engineering Studies

Chattez avec Graph Search

Molecular reconstruction and simulation of the Neuron-Glia-Vasculature system

Proteome adaptations of the organohalide-respiring Desulfitobacterium hafniense strain DCB-2 to various energy metabolisms

From Automated Bootstrapping to Collaborative Editing: A Framework for 4D City Reconstruction

De novo design of protein interactions with learned surface fingerprints

Basic Mechanisms of Immunometabolites in Shaping the Immune Response

Genomics of Preaxostyla Flagellates Illuminates the Path Towards the Loss of Mitochondria

Determining an optimum quantity of interleaved instruction streams of defined coroutines

AIDRES: A database for the decarbonisation of the heavy industry in Europe

Inter- and intra-individual variability in CO2 production and metabolic rate

Early Neuroprotective Effects of Bovine Lactoferrin Associated with Hypothermia after Neonatal Brain Hypoxia-Ischemia in Rats

Nutritional metabolism and cerebral bioenergetics in Alzheimer's disease and related dementias

Efficient Concurrent Analytical Query Processing using Data and Workload-conscious Sharing