Publications associées à Compensation of visual backward masking deficits in relatives of schizophrenia patients

Publications associées (36)

A Longitudinal and Reproducible Anti-coactivation Pattern Between the Cerebellum and the Ventral Tegmental Area Relates to Apathy in Schizophrenia

Dimitri Nestor Alice Van De Ville, Farnaz Delavari

Negative symptoms of schizophrenia lack effective treatments. Anomalies in the reward system and cerebellum have been linked to these symptoms. The cerebellum modulates reward circuitry via the ventral tegmental area (VTA). The "cognitive dysmetria theory" ...

Elsevier BV2025

Sex modulation of faces prediction error in the autistic brain

Sylvain Jean-François Harquel

Recent research suggests that autistic females may have superior socio-cognitive abilities compared to autistic males, potentially contributing to underdiagnosis in females. However, it remains unclear whether these differences arise from distinct neurophy ...

Nature Portfolio2024

Acute optogenetic induction of the prodromal endophenotype of CA1 hyperactivity causes schizophrenia-related deficits in cognition and salience attribution

Christina Maria Grimm

Hyperactivity of the human anterior hippocampus has been reported to spread from its CA1 subfield to the subiculum around the onset of first-episode psychosis and could be a cellular target for early therapeutic intervention in the schizophrenia prodrome. ...

NATURE PORTFOLIO2024

Multimodal Neural Correlates of Childhood Psychopathology

Vanessa Siffredi

Complex structural and functional changes occurring in typical and atypical development necessitate multidimensional approaches to better understand the risk of developing psychopathology. Here, we simultaneously examined structural and functional brain ne ...

eLIFE SCIENCES PUBL LTD2024

An immersive virtual reality tool for assessing left and right unilateral spatial neglect

Olaf Blanke, Andrea Serino, Roberta Ronchi

The reported rate of the occurrence of unilateral spatial neglect (USN) is highly variable likely due to the lack of validity and low sensitivity of classical tools used to assess it. Virtual reality (VR) assessments try to overcome these limitations by pr ...

Wiley2024

The neuropsychology and neuroanatomy of reduplicative paramnesia

Olaf Blanke

Reduplicative paramnesia refers to the delusional belief that there are identical places in different locations. In this case-control study we investigated the clinical, phenomenological, neuropsychological and neuroanatomical data of eleven patients with ...

ELSEVIER MASSON, CORP OFF2023

Molecular reconstruction and simulation of the Neuron-Glia-Vasculature system

Polina Shichkova

The outstanding information processing capacity of the brain relies on numerous molecular mechanisms. It is an extremely energy-expensive function, which involves specialization and collaboration of different cell types. A common framework to study the com ...

EPFL2023

Glucocorticoid-based pharmacotherapies preventing PTSD

Maria del Carmen Sandi Perez, Silvia Monari

Posttraumatic stress disorder (PTSD) is a highly disabling psychiatric condition that may arise after exposure to acute and severe trauma. It is a highly prevalent mental disorder worldwide, and the current treatment options for these patients remain limit ...

2023

Comparison of Responses to DCN vs. VCN Stimulation in a Mouse Model of the Auditory Brainstem Implant (ABI)

Stéphanie Lacour, Nicolas Vachicouras, Florent-Valéry Coen

The auditory brainstem implant (ABI) is an auditory neuroprosthesis that provides hearing to deaf patients by electrically stimulating the cochlear nucleus (CN) of the brainstem. Whether such stimulation activates one or the other of the CN's two major sub ...

SPRINGER2022

Topology of synaptic connectivity constrains neuronal stimulus representation, predicting two complementary coding strategies

Michael Reimann, Ran Levi, Christoph Pokorny

In motor-related brain regions, movement intention has been successfully decoded from invivo spike train by isolating a lower-dimension manifold that the high-dimensional spiking activity is constrained to. The mechanism enforcing this constraint remains u ...

PUBLIC LIBRARY SCIENCE2022

Functional connectivity underlying cognitive and psychiatric symptoms in post-COVID-19 syndrome: is anosognosia a key determinant?

Dimitri Nestor Alice Van De Ville, Alessandra Griffa

Lack of awareness of cognitive impairment (i.e. anosognosia) could be a key factor for distinguishing between neuropsychological postCOVID-19 condition phenotypes. In this context, the 2-fold aim of the present study was to (i) establish the prevalence of ...

2022

Timing is Everything

Karen Adam

In this thesis, timing is everything. In the first part, we mean this literally, as we tackle systems that encode information using timing alone. In the second part, we adopt the standard, metaphoric interpretation of this saying and show the importance of ...

EPFL2022

Uncovering the neural encoding of behavior in the adult Drosophila motor system

Chin-Lin Chen

One of the most important goals in neuroscience research has always been to understand how animals control their behavior. However, the long focus on the role of brain neurons in behavioral control might be missing the full story. In fact, brain-wide fluct ...

EPFL2022

The shine-through paradigm and the schizophrenia spectrum: a summary

Michael Herzog, Maya Roinishvili, Janir Nuno Ramos Antunes Da Cruz, Ophélie Gladys Favrod, Simona Adele Garobbio

In the past 10 years, our laboratory has proved the shine-through paradigm to be a very sensitive endophenotype for schizophrenia. The shine-through paradigm is a visual backward masking task, where the target is a vertical vernier followed by a 25-element ...

2021

Clustering and control for adaptation uncovers time-warped spike time patterns in cortical networks in vivo

James Bryden Isbister

How information in the nervous system is encoded by patterns of action potentials (i.e. spikes) remains an open question. Multi-neuron patterns of single spikes are a prime candidate for spike time encoding but their temporal variability requires further c ...

Nature Research2021

Electrophysiological correlates of visual backward masking in patients with bipolar disorder

Michael Herzog, Maya Roinishvili, Janir Nuno Ramos Antunes Da Cruz, Ophélie Gladys Favrod, Simona Adele Garobbio

In visual backward masking (VBM), a target is followed by a mask that decreases target discriminability. Schizophrenia patients (SZ) show strong and reproducible masking impairments, which are associated with reduced EEG amplitudes. Patients with bipolar d ...

2021

Neural Compensation Mechanisms of Siblings of Schizophrenia Patients as Revealed by High-Density EEG

Michael Herzog, Maya Roinishvili, Patricia Figueiredo, Albulena Jashari-Shaqiri, Janir Nuno Ramos Antunes Da Cruz, Ophélie Gladys Favrod

Visual backward masking (VBM) deficits are candidate endophenotypes of schizophrenia indexing genetic liability of the disorder. In VBM, a target is followed by a mask that deteriorates target perception. Schizophrenia patients and, to a lesser extent, the ...

2020

P300 in the park: feasibility of online data acquisition and integration in a Mobile Brain/Body Imaging setting

Silvestro Micera, Fiorenzo Artoni

In the last years Mobile Brain/Body Imaging (MoBI) has been increasingly used to study cognition in the real world to give more ecological validity to brain imaging studies currently carried out only inside the lab. To increase portability of the setup and ...

IEEE2019

Spatial covariance improves BCI performance for late ERPs components with high temporal variability

José del Rocio Millán Ruiz, Ricardo Andres Chavarriaga Lozano, Lucian Andrei Gheorghe, Marija Uscumlic, Ruslan Aydarkhanov

Objective. Event Related Potentials (ERPs) reflecting cognitive response to external stimuli, are widely used in brain computer interfaces. ERP waveforms are characterized by a series of components of particular latency and amplitude. The classical ERP dec ...

2020

Neural dynamics of the competition between grouping organizations

Michael Herzog, Ophélie Gladys Favrod, Einat Rashal

Neural dynamics of the competition between grouping organizations have been studied to a limited extent. The paradigms used so far confounded grouping operations with task demands, using explicit reports of the predominantly perceived organization and bias ...

SAGE PUBLICATIONS LTD2019