Development of functionalized alginate-based hydrogels to reduce fibrosis in the transplantation of microencapsulated cells

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Accurately assessing the interfacial composition and reactivity of (bio)polymers under controlled but environmentally relevant conditions remains challenging. This study explores the evolution of surface functionalities of novel polyesters Poly(Butylene Xy ...

Nature creates hydrogels--soft, water-rich materials--with stiffness and toughness spanning over six orders of magnitude. These materials fulfill diverse biological functions tailored to mechanical demands. Inspired by this versatility, synthetic hydrogels ...

Dwindling fossil resources and their associated environmental concerns have increased interest in biobased products. In particular, many approaches to convert lignocellulosic biomass into small-molecule building blocks are being explored via thermal, chemi ...

It is well-established that symptomatic cancers evade immune destruction by coalescing tumor microenvironments to suppress adaptive immunity. Additionally, mouse models of cervical and other cancers have revealed a capability of tumors to systemically indu ...

This paper describes the synthesis of supramolecular polymer brushes via surface-initiated polymerization from adamantane-functionalized initiators that are noncovalently bound to beta-cyclodextrin- or cucurbit[7]uril-modified substrates. Surface-initiated ...

Background & Aims: Current therapies for the treatment of alcohol-related liver disease (ALD) have proven largely ineffective. Patients relapse and the disease progresses even after liver transplantation. Altered epigenetic mechanisms are characteristic of ...

A common method for creating compliant electrodes for dielectric elastomer actuators (DEAs) and soft sensors is to incorporate electrically conductive carbon particles into a polymer matrix. However, using unidirectional aligned carbon fibers instead not o ...

Supramolecular interactions play an important role in defining the structure and the resulting mechanical properties of materials. For instance, interchain hydrogen-bonding in PAs gives them superior strength and stiffness in engineering materials, while t ...

Mechanochemistry harnesses mechanical force to facilitate chemical reactions. Traditionally, the field of polymer mechanochemistry has used methods to activate chemical bonds, which use forces that are larger than those that are required to break a covalen ...

The conception of epoxy thermosets with both reprocessability and flame retardancy delineates a new horizon in polymer science, offering a material solution that is not only superior in fire safety but is also environment friendly. Herein, a flame-retardan ...

Polymer brushes, which are polymers anchored to a solid substrate by one chainend, have the ability to modify the properties of an underlying substrate, offering intriguing features such as enhanced lubrication, reduced friction, colloidal stability, and a ...

The wetting dynamics of molten thermoplastic polymers, which are known to influence the force balance of the triple line, are not understood properly despite their importance in many industrial processes. In particular, the influence of the molecular weigh ...

Polymers play a central role in shaping our world across various fields, but their heavy reliance on petrochemicals poses climate change, environmental and health risks. To address and alleviate these issues, transitioning to sustainable polymers, sourced ...

With its exceptional biocompatibility, alginate emerged as a highly promising biomaterial for a large range of applications in regenerative medicine. Whether in the form of microparticles, injectable hydrogels, rigid scaffolds, or bioinks, alginate provide ...

Dielectric elastomer actuators (DEA) are elastic capacitors composed of a pair of compliant electrodes and a soft dielectric elastomer film sandwiched in between. This kind of stretchable capacitors can be actuated when charged, can generate electricity fr ...

Ought to their bioinert properties and facile synthesis, poly[(oligoethylene glycol)methacrylate]s (POEGMAs) have been raised as attractive alternatives to poly(ethylene glycols) (PEGs) in an array of (bio)material applications, especially when they are ap ...

Chlorinated compounds are ubiquitous. However, accumulation of chlorine-containing waste has a negative impact on human health and the environment due to the inapplicability of common disposal methods, such as landfill and incineration. Here we report a su ...

Bio-based resins, obtained from renewable raw materials, are a more sustainable alternative to oil-based resins for fiber-reinforced polymer (FRP) composites. The incorporation of lignin in those resins has the potential to enhance their performance. This ...

The efficacy of anti-cancer therapies depends on the genomic composition of the tumor, its microenvironment, spatial organization, and intra-tumor heterogeneity. B-cell lymphomas are a heterogeneous group of tumors emerging from B-cells at different stages ...

The drive to develop cartilage implants for the treatment of major defects in the musculoskeletal sys-tem has resulted in a major research thrust towards developing biomaterial devices for cartilage repair. Investigational devices for the restoration of ar ...

Development of functionalized alginate-based hydrogels to reduce fibrosis in the transplantation of microencapsulated cells

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Characterization of Biobased Polymers at the Gas-Solid Interface─Analysis of Surface and Bulk Properties during Artificial Degradation

Engineering the Mechanics of Microstructured Hydrogels

Aldehyde-Stabilization Strategies for Building Biobased Consumer Products around Intact lignocellulosic Structures

HPV16-Expressing Tumors Release Multiple IL-1 Ligands to Orchestrate Systemic Immunosuppression Whose Disruption Enables Efficacy of a Therapeutic Vaccine

Supramolecular Polymer Brushes Grafted via Atom Transfer Radical Polymerization from Surfaces Presenting Non-covalent, Host-Guest Complex-Based Initiators

Anti-miR-873-5p improves alcohol-related liver disease by enhancing hepatic deacetylation via SIRT1

Highly anisotropic carbon fiber electrodes for DEAs and their dynamic non-monotonic conductive properties

Supramolecular Modifications of Semicrystalline Polymers

Soft Mechanochemistry of Disulfide-Crosslinked Polymer Networks

Enabling simultaneous reprocessability and fire protection via incorporation of phosphine oxide monomer in epoxy vitrimer

Architecturally Diverse Polymer Brushes Prepared via Surface-Initiated Atom Transfer Radical Polymerization

Influence of the molecular weight and physical properties of a thermoplastic polymer on its dynamic wetting behavior

New Polymers from Biomass-Derived Hydroxycinnamic Acid Derivatives

Recent Advances in Alginate-Based Hydrogels for Cell Transplantation Applications

Bottlebrush Dielectric Elastomers with Improved Properties for Actuation

The Structural Dispersity of Oligoethylene Glycol-Containing Polymer Brushes Determines Their Interfacial Properties

Tandem catalysis enables chlorine-containing waste as chlorination reagents

Incorporation of Lignin in Bio-Based Resins for Potential Application in Fiber-Polymer Composites

Development of patient-derived lymphomoids with preserved tumor architecture for lymphoma therapy screening

A guide to preclinical evaluation of hydrogel-based devices for treatment of cartilage lesions