Evidence Of Adaptation From Ancestral Variation In Young Populations Of Beach Mice

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Background: Reproductive isolation can result from adaptive processes (e.g., ecological speciation and mutation-order speciation) or stochastic processes such as "system drift" model. Ecological speciation predicts barriers to gene flow between populations ...

Glacier-fed streams are the cold, ultra-oligotrophic, and unstable streams that are fed by glacial meltwater. Despite these extreme conditions, they harbour a diverse and abundant microbial diversity that develops into biofilms, covering the boulders and s ...

Global change exposes ecosystems to changes in the frequency, magnitude, and concomitancy of disturbances, which impact the composition and functioning of these systems. Here, we experimentally evaluate the effects of salinity disturbances and eutrophicati ...

Microorganisms are a key component in the chain of life. They are essential for agriculture, produce a large proportion of oxygen, and play a central role in the cycle of elements. Microorganisms are widely used in the production of food and alcoholic beve ...

Viral metagenomics is a useful tool for detecting multiple human viruses in urban sewage. However, more refined protocols are required for its effective use in disease surveillance. In this study, we investigated the performance of three different preampli ...

Traditional martial arts are treasures of humanity's knowledge and critical carriers of sociocultural memories throughout history. However, such treasured practices have encountered various challenges in knowledge transmission and now feature many entries ...

Background: We previously described the KINSSHIP syndrome, an autosomal dominant disorder associated with intellectual disability (ID), mesomelic dysplasia and horseshoe kidney,caused by de novo variants in the degron of AFF3. Mouse knock-ins and overexpre ...

Aims. We derived galaxy colour selections from Euclid and ground-based photometry, aiming to accurately define background galaxy samples in cluster weak-lensing analyses. These selections have been implemented in the Euclid data analysis pipelines for gala ...

Growing evidence indicates that transposable elements (TEs) play important roles in evolution by providing genomes with coding and non-coding sequences. Identification of TE-derived functional elements, however, has relied on TE annotations in individual s ...

The adaptation of organisms to their environment depends on the innovative potential inherent to genetic variation. In complex organisms such as mammals, processes like development and immunity require tight gene regulation. Complex forms emerge more often ...

Geomembrane systems have been used at hydropower plants as rehabilitation and mitigation technology for several decades and are now used worldwide. In the context of planning an energy transition that promotes the sustainable use of water resources for ene ...

It is of great interest to the energy community to understand how the mechano-physico-chemical phenomena that eventually lead to device degradation are related to the startup, operation, and shutdown phases. For electrocatalytic systems operating in liquid ...

Cis-genetic effects are key determinants of transcriptional divergence in discrete tissues and cell types. However, how cis- and trans-effects act across continuous trajectories of cellular differentiation in vivo is poorly understood. Here, we quantify al ...

Long-term consumption of lipid-rich foods can contribute to common metabolic diseases and systemic low-grade inflammation. However, dietary responses and the development of non-communicable diseases are shaped by genetic factors and gene-by-environment int ...

The question of how local adaptation takes place remains a fundamental question in evolutionary biology. The variation of allele frequencies in genes under selection over environmental gradients remains mainly theoretical and its empirical assessment would ...

The arms race between viruses and their hosts shaped the evolutionary history and the genome composition of both parties. Restriction factors are the first-line antiviral effectors encoded by the host genomes and are often conserved through evolution to pr ...

Owing to stochastic fluctuations arising from finite population size, known as genetic drift, the ability of a population to explore a rugged fitness landscape depends on its size. In the weak mutation regime, while the mean steady-state fitness increases ...

Characterizing the genetic structure of large cohorts has become increasingly important as genetic studies extend to massive, increasingly diverse biobanks. Popular methods decompose individual genomes into fractional cluster assignments with each cluster ...

Investigating the intangible nature of a cultural domain can take multiple forms, addressing for example the aesthetic, epistemic and social dimensions of its phenomenology. The context of Southern Chinese martial arts is of particular significance as it c ...

Many eukaryotes form multinucleated cells during their devel-opment. Some cells persist as such during their lifetime, others choose to cleave each nucleus individually using a specialized cytokinetic process known as cellularization. What is cellula-rizat ...

Evidence Of Adaptation From Ancestral Variation In Young Populations Of Beach Mice

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Reproductive isolation arises during laboratory adaptation to a novel hot environment

The microbial genomics of glacier-fed streams: adaptations to an extreme ecosystem

The cost of adaptability: resource availability constrains functional stability under pulsed disturbances

Reconstruction and analysis of genome-scale metabolic networks in single organisms and microbial communities

Comparison of Three Viral Nucleic Acid Preamplification Pipelines for Sewage Viral Metagenomics

Ontology-based Knowledge Representation for Traditional Martial Arts

Variant-specific pathophysiological mechanisms of AFF3 differently influence transcriptome profiles

Euclid preparation XXXVII. Galaxy colour selections with Euclid and ground photometry for cluster weak-lensing analyses

Ancestral genome reconstruction enhances transposable element annotation by identifying degenerate integrants

Meeting our Makers: Uncovering the cis-regulatory activity of transposable elements using statistical learning

A comprehensive review on geomembrane systems application in hydropower

Quasi-operando Transmission Electron Microscopy Diagnostics for Electrocatalytic Processes in Liquids

The dynamic genetic determinants of increased transcriptional divergence in spermatids

Identifying genetic and dietary modulators of metabolic disorders using systems genetics

Multiple genomic solutions for local adaptation in two closely related species (sheep and goats) facing the same climatic constraints

PSGL-1 is an evolutionarily conserved antiviral restriction factor

Impact of population size on early adaptation in rugged fitness landscapes

Neural ADMIXTURE for rapid genomic clustering

The Facets of Intangible Heritage in Southern Chinese Martial Arts: Applying a Knowledge-Driven Cultural Contact Detection Approach

Cellularization across eukaryotes: Conserved mechanisms and novel strategies