Micromotion and fluid flow around cementless femoral components in total hip arthroplasty

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Sensorineural hearing loss is a profound form of deafness, arising from damage to cochlear hair cells, which can be treated by limited clinical options such as cochlear implants. However, the implantation procedure carries the inherent risk of electrode in ...

We consider fluid flows, governed by the Navier-Stokes equations, subject to a steady symmetry-breaking bifurcation and forced by a weak noise acting on a slow timescale. By generalizing the multiple-scale weakly nonlinear expansion technique employed in t ...

Understanding the corrosion behavior of biomedical materials in the human body is an essential step for the development of improved materials and clinical procedures in arthroplasty. In this work, the corrosion behavior of Ti and CoCrMo alloys in human syn ...

This thesis presents an extensive exploration of neuroelectronic interfaces, focusing on microfabrication, in silico modeling, and their applications in designing and fabricating devices for neural interfacing. The research encompasses both peripheral nerv ...

Background: Osteochondritis dissecans (OCD) of the humeral capitellum is an important cause of elbow disability in young athletes. Large and unstable lesions sometimes require joint reconstruction with osteochondral autograft. Several approaches have been ...

Deep learning models (DLM) are efficient replacements for computationally intensive optimization techniques. Musculoskeletal models (MSM) typically involve resource-intensive optimization processes for determining joint and muscle forces. Consequently, DLM ...

The thesis is dedicated to the study of two main partial differential equations (PDEs) in fluid dynamics: the Navier-Stokes equations, which describe the motion of incompressible fluids, and the transport equation with divergence-free velocity fields, whic ...

Implantable neural interfaces with the central and peripheral nervous systems are currently used to restore sensory, motor, and cognitive functions in disabled people with very promising results. They have also been used to modulate autonomic activities to ...

Microcomputed tomography (mu CT) is a nondestructive X-ray imaging method used in plant physiology to visualize in situ plant tissues that enables assessments of embolized xylem vessels. Whereas evidence for X-ray-induced cellular damage has been reported, ...

Neuroprostheses have been used clinically for decades, to help restore or preserve brain functions, when pharmaceutical treatments are inefficient. Although great progress in the field has been made over the years to interface with the nervous system, surf ...

Purpose The aim of this study was to develop a novel approach for predicting the expression status of Epidermal Growth Factor Receptor (EGFR) and its subtypes in patients with Non-Small Cell Lung Cancer (NSCLC) using a Three-Dimensional Convolutional Neura ...

Nowadays, Liquid Composite Molding techniques are often used to manufacture high quality fiber reinforced composite parts at a relatively low cost. These involve an infiltration process, in which a liquid resin is forced to ingress into a dry fibrous porou ...

We seek to address how air entrapment mechanisms during infiltration are influenced by the wetting characteristics of the fluid and the pore network formed by the reinforcement. To this end, we evaluated the behavior of two model fluids with different surf ...

A unified numerical framework is presented for the modelling of multiphasic viscoelastic and elastic flows. The rheologies considered range from incompressible Newtonian or Oldroyd-B viscoelastic fluids to Neo-Hookean elastic solids. The model is formulate ...

Hydraulic stimulation of enhanced deep geothermal reservoirs commonly targets pre-existing joint networks with the goal of increasing reservoir permeability. Here, we study the permeability and strength of joint-free and jointed Buntsandstein sandstones fr ...

The present relates to a system for automated cell culture, the system comprising an inflow module, a cell culture plate and an outflow module, said inflow module being in fluid connection with the outflow module via the cell culture plate, the inflow modu ...

Fluidic systems enable actuation in various applications, such as automotive, medical, and industrial robotics. Miniaturized valves constitute a fundamental controlling element of modern fluidic systems, intriguing the interest of many researchers. This le ...

The brain is an ultra-soft viscoelastic matrix. Sub-kPa hydrogels match the brain's mechanical properties but are challenging to manipulate in an implantable format. We propose a simple fabrication and processing sequence, consisting of de-hydration, patte ...

The drive to develop cartilage implants for the treatment of major defects in the musculoskeletal sys-tem has resulted in a major research thrust towards developing biomaterial devices for cartilage repair. Investigational devices for the restoration of ar ...

The understanding of cell-cell and cell-matrix interactions via receptor and ligand binding relies on our ability to study the very first events of their contact. Of particular interest is the interaction between a T cell receptor and its cognate peptide-m ...

Micromotion and fluid flow around cementless femoral components in total hip arthroplasty

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Additive manufacturing of flexible, biodegradable drug implants for sustained multi-drug release into the cochlea

Noise-induced transitions past the onset of a steady symmetry-breaking bifurcation: The case of the sudden expansion

Assessment of in-vivo corrosion of Ti and CoCrMo joint implants by electrochemical measurements in human synovial liquids

Modeling, fabrication and validation of 3D neural interfaces for peripheral nerves and brain organoids

Surgical approaches to the capitellum: a comparative anatomic study

Glenohumeral joint force prediction with deep learning

Anomalous dissipation and other non-smooth phenomena in fluids

Organ Neuroprosthetics: Connecting Transplanted and Artificial Organs with the Nervous System

In vivo X-ray microtomography locally affects stem radial growth with no immediate physiological impact

Unraveling behavior and cortical signals to guide the development of soft neuroprostheses for auditory restoration and spreading depolarization

Advancing EGFR mutation subtypes prediction in NSCLC by combining 3D pretrained ConvNeXt, radiomics, and clinical features

Visualization and modelling of dynamic flow in fibrous preforms for liquid composite molding

Effect of wettability and textile architecture on fluid displacement and pore formation during infiltration of carbon fibrous preforms

Numerical simulation of immiscible incompressible viscous, viscoelastic and elastic multiphase flows

Reactivation of variably sealed joints and permeability enhancement in geothermal reservoir rocks

System for automated and dynamic cell culture

Highly Efficient Miniaturized Magnetorheological Valves Using Electropermanent Magnets

Revealing the complexity of ultra-soft hydrogel re-swelling inside the brain

A guide to preclinical evaluation of hydrogel-based devices for treatment of cartilage lesions

Microfluidic device combining hydrodynamic and dielectrophoretic trapping for the controlled contact between single micro-sized objects and application to adhesion assays