Publication

Visual backward masking deficits are specific to female observers scoring high on cognitive disorganisation

2013
Conference Papers

Résumé

Visual backward masking (VBM) deficits are a potential endophenotype of schizophrenia. VBM deficits were found in schizophrenic patients, in their unaffected relatives, and in healthy students scoring high in "cognitive disorganisation" (CD; Cappe et al., 2012). In the latter study we found post-hoc that females seemed to be stronger affected than males. This hypothesis was tested here in a fresh sample of 29 male and 27 female students varying in their self-reported schizotypy scores. In addition, we tested performance in Wisconsin Card Sorting Task (WCST). As expected, we found significant VBM deficits in female students scoring high in CD but not in the males. We found no significant WCST deficits in individuals scoring high in CD. Our results add further evidence that VBM is a potential endophenotype of schizophrenia. Future research will investigate whether sex differences in VBM are related to hormonal differences or a sex-specific bias in the self-reports.

Source officielle

https://infoscience.epfl.ch/entities/publication/273dac6f-9080-49f9-908f-d004668a4d8a

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2013
Conference Papers

Résumé

Source officielle

https://infoscience.epfl.ch/entities/publication/273dac6f-9080-49f9-908f-d004668a4d8a

À propos de ce résultat

Concepts associés (32)

Cognitive flexibility

Cognitive flexibility is an intrinsic property of a cognitive system often associated with the mental ability to adjust its activity and content, switch between different task rules and corresponding behavioral responses, maintain multiple concepts simultaneously and shift internal attention between them. The term cognitive flexibility is traditionally used to refer to one of the executive functions. In this sense, it can be seen as neural underpinnings of adaptive and flexible behavior.

Executive dysfunction

In psychology and neuroscience, executive dysfunction, or executive function deficit, is a disruption to the efficacy of the executive functions, which is a group of cognitive processes that regulate, control, and manage other cognitive processes. Executive dysfunction can refer to both neurocognitive deficits and behavioural symptoms. It is implicated in numerous psychopathologies and mental disorders, as well as short-term and long-term changes in non-clinical executive control.

Test neuropsychologique

Un test neuropsychologique est un questionnaire, une échelle ou un paradigme permettant d'évaluer le bon fonctionnement des fonctions ou processus cognitifs comme la mémoire, le langage, la planification, l'attention, la prise de décision, etc. Ces fonctions étant sous-tendues biologiquement par une région cérébrale, ou plus généralement par un réseau de régions cérébrales, le test neuropsychologique est également utilisé pour évaluer l'intégrité de ces structures au sein du cerveau.

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Publications associées (9)

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Visual backward masking deficits are specific to female observers scoring high on cognitive disorganisation

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