Publications associées à Apparent compensation mechanisms in relatives of schizophrenia patients in visual backward masking

The shine-through paradigm and the schizophrenia spectrum: a summary

Michael Herzog, Maya Roinishvili, Ophélie Gladys Favrod, Simona Adele Garobbio, Janir Nuno Ramos Antunes Da Cruz

In the past 10 years, our laboratory has proved the shine-through paradigm to be a very sensitive endophenotype for schizophrenia. The shine-through paradigm is a visual backward masking task, where the target is a vertical vernier followed by a 25-element ...

2021

Neural Compensation Mechanisms of Siblings of Schizophrenia Patients as Revealed by High-Density EEG

Michael Herzog, Maya Roinishvili, Ophélie Gladys Favrod, Patricia Figueiredo, Albulena Jashari-Shaqiri, Janir Nuno Ramos Antunes Da Cruz

Visual backward masking (VBM) deficits are candidate endophenotypes of schizophrenia indexing genetic liability of the disorder. In VBM, a target is followed by a mask that deteriorates target perception. Schizophrenia patients and, to a lesser extent, the ...

2020

Time course of prediction errors in sequential decision making

Michael Herzog, He Xu

In reinforcement learning, an agent makes sequential decisions to maximize reward. During learning, the actual and expected outcome are compared to tell whether a decision was good or bad. The difference between the actual outcome and expected outcome is t ...

2018

Visual masking and schizophrenia: enhancement deficit 200 ms after stimulus onset

Michael Herzog, Maya Roinishvili, Ophélie Gladys Favrod, Janir Nuno Ramos Antunes Da Cruz

Masking is strongly deteriorated in schizophrenia patients and to a lesser extent in their healthy relatives. For this reason, masking is a good endophenotype. Here, we show the EEG correlates of masking across the schizophrenia continuum in order to tackl ...

2018

Visual backward masking and the schizophrenia spectrum: EEG correlates

Michael Herzog, Maya Roinishvili, Ophélie Gladys Favrod, Albulena Jashari-Shaqiri, Janir Nuno Ramos Antunes Da Cruz

Schizophrenia is a heterogeneous disease strongly influenced by genetic factors. We have previously shown that visual backward masking (VBM) is a very sensitive endophenotype of schizophrenia (Chkonia et al., 2010). Importantly, not only patients but also ...

2017

Electrophysiological correlates of visual backward masking in high schizotypic personality traits participants

Michael Herzog, Maya Roinishvili, Ophélie Gladys Favrod, Guillaume Sierro, Christine Mohr

Visual backward masking is strongly deteriorated in patients with schizophrenia. Masking deficits are associated with strongly reduced amplitudes of the global field power in the EEG. Healthy participants who scored high in cognitive disorganization (a sch ...

Elsevier2017

Neural Correlates of Sequential Decision Making

Michael Herzog, He Xu

In chess, a series of moves is made until a delayed sparse feedback (win, loss) is issued, which makes it impossible to evaluate the value of a single move. There are powerful reinforcement learning (RL) algorithms, which can cope with these sequential dec ...

2017

Neural Correlates of Sequential Decision Making

Michael Herzog, He Xu

In chess, a series of moves is made until a delayed sparse feedback (win, loss) is issued, which makes it impossible to evaluate the value of a single move. There are powerful reinforcement learning (RL) algorithms, which can cope with these sequential dec ...

2017

Compensation of visual backward masking deficits in relatives of schizophrenia patients

Michael Herzog, Maya Roinishvili, Patricia Figueiredo, Janir Nuno Ramos Antunes Da Cruz

Visual backward masking (VBM) is a potential endophenotype of schizophrenia reflecting the genetic underpinnings of the disease (Chkonia et al., 2010). Masking deficits are highly correlated with reduced N1 amplitudes as shown by the Global Field Power (GF ...

2016

Neural correlates of visual backward masking: Compensation mechanism in relatives of schizophrenia patients

Michael Herzog, Maya Roinishvili, Patricia Figueiredo, Janir Nuno Ramos Antunes Da Cruz

Visual backward masking (VBM) is a very sensitive endophenotype of schizophrenia. Masking deficits are highly correlated with reduced EEG amplitudes. In VBM, a target stimulus is followed by a mask, which decreases performance on the target. Here, we inves ...

2016

Electrophysiological Correlates of Visual Backward Masking in Schizotypy

Michael Herzog, Ophélie Gladys Favrod, Guillaume Sierro, Christine Mohr

Visual deficits are well documented in schizophrenia. For example, a Vernier is followed by a blank inter-stimulus interval (ISI) and then a grating mask. Observers indicate the direction of the Vernier offset (left vs right). Patients need ISIs that are 1 ...

2016

EEG Correlates of Backward Masking in Schizotypy

Michael Herzog, Maya Roinishvili, Ophélie Gladys Favrod, Guillaume Sierro, Christine Mohr

Visual deficits are well documented in schizophrenia, especially in backward masking. In our task a Vernier is followed by a blank inter-stimulus interval (ISI) and then a grating mask. Observers indicate the direction of the Vernier offset (left vs right) ...

2016

The electrophysiological effects of the serotonin 1A receptor agonist buspirone in emotional face processing

Fosco Bernasconi

Emotional face processing is critically modulated by the serotonergic system, and serotonin (5-HT) receptor agonists impair emotional face processing. However, the specific contribution of the 5-HT1A receptor remains poorly understood. Here we investigated ...

Elsevier Science Bv2015

Endophenotypes of schizophrenia: electrophysiological correlates of first episode patients

Michael Herzog, Maya Roinishvili, Ophélie Gladys Favrod, Albulena Jashari-Shaqiri

Schizophrenia is a heterogeneous disorder and among other symptoms, patients have important visual impairments. Visual paradigms are therefore important tools to investigate the mechanisms of schizophrenia. During the last period of the NCCR, we have chara ...

2015

Inverse Solutions for Brain Computer Interface

José del Rocio Millán Ruiz, Mohit Kumar Goel

Inverse solution allows to estimate sources that generate a given scalp EEG topography. Recently, it has been used in Brain Computer Interfaces (BCIs) to extract robust features based on the hypothesis that projection onto the source space (high dimensiona ...

EPFL2013

Reduced Fronto-Temporal and Limbic Connectivity in the 22q11.2 Deletion Syndrome: Vulnerability Markers for Developing Schizophrenia?

Jean-Philippe Thiran, Marie Schaer, Leila Cammoun

The 22q11.2 deletion syndrome (22q11DS) is a widely recognized genetic model allowing the study of neuroanatomicalvbiomarkers that underlie the risk for developing schizophrenia. Recent advances in magnetic resonance image analysesvenable the examination o ...

Public Library of Science2013

Event-related potentials and changes of brain rhythm oscillations during working memory activation in patients with first-episode psychosis

Jonas Richiardi

Background: Earlier contributions have documented significant changes in sensory, attention-related endogenous event-related potential (ERP) components and theta band oscillatory responses during working memory activation in patients with schizophrenia. In ...

2012