Recent Advances and Prospects in the Research of Nascent Adhesions

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Publications associées (27)

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Communication across membranes controls critical cellular processes and is achieved by receptors translating extracellular signals into selective cytoplasmic responses. While receptor tertiary structures can be readily characterized, receptor associations ...

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Science on the Summit: Exploring Scientific Tourism Through the Lens of Eighteenth Century Mountain Ascents

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This contribution argues that a particular scientific context made summits a place of interest for eighteenth-century travelers. This development is connected to two particular scientific practices. First, the challenges raised by making the barometer into ...

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Differential impact of TGF beta/SMAD signaling activity elicited by Activin A and Nodal on endoderm differentiation of epiblast stem cells

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Allocation of cells to an endodermal fate in the gastrulating embryo is driven by Nodal signaling and consequent activation of TGF beta pathway. In vitro methodologies striving to recapitulate the process of endoderm differentiation, however, use TGF beta ...

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The role of eosinophils in breast cancer

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Eosinophils are granulocytes and belong to the innate arm of immunity. Eosinophils can be in different basal or activation states and depending on which type of activation is applied, they exert different effector functions. These multi-functional cells ha ...

EPFL2022

Combating Online Scientific Misinformation

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The drastic shift towards digital communication in our mediasphere has caused a profound change in the production and consumption of information, which in turn has substantial implications on the social and political landscape. Misinformation, as a side ef ...

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Engineered Extracellular Matrices with Integrated Wireless Microactuators to Study Mechanobiology

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Mechanobiology explores how forces regulate cell behaviors and what molecular machinery are responsible for the sensing, transduction, and modulation of mechanical cues. To this end, probing of cells cultured on planar substrates has served as a primary ex ...

Wiley2021

Metabolic and transcriptomic profiles of glioblastoma invasion revealed by comparisons between patients and corresponding orthotopic xenografts in mice

Lijing Xin, Cristina Ramona Cudalbu, Mario Gaetano Lepore, Marta Lai

The invasive behavior of glioblastoma, the most aggressive primary brain tumor, is considered highly relevant for tumor recurrence. However, the invasion zone is difficult to visualize by Magnetic Resonance Imaging (MRI) and is protected by the blood brain ...

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