Publications associées à Preparation of Single-Somite Explants from Zebrafish Embryos

Publications associées (36)

Comments on the Hox timer and related issues

In particular, this sequence is found in the 39 members of the amniote Hox gene family, a series of genes activated in mid-gastrulation and involved in organizing morphologies along the extending anterior to posterior (AP) body axis. Over the past 30 years ...

2025

Heartbeat on repeat: noncanonical KZFP and its transposable element targets shape cardiac cell specification

Danica Milovanovic

KRAB Zinc Finger Proteins (KZFPs) are a large mammalian transcription factor family, which has mainly been studied for its ability to silence and tame transposable elements (TEs) - a controlling effect brought by the ubiquitous KZFP protein partner, TRIM28 ...

EPFL2025

Customized modular multi-material mouthguard and method of making the same

Dominique Pioletti, Naser Nasrollahzadeh Mamaghani, Martin Broome

There is described a mouthguard comprising an externally exposed impact protective region defined by a first material property and configured to cover a front tooth, an internally exposed occlusional cushioning region defined by a second material property ...

2024

Computational Homogenization for Inverse Design of Surface-based Inflatables

Mark Pauly, Florin Isvoranu, Francis Julian Panetta, Yingying Ren, Seiichi Eduardo Suzuki Erazo, Uday Kusupati

Surface-based inflatables are composed of two thin layers of nearly inextensible sheet material joined together along carefully selected fusing curves. During inflation, pressure forces separate the two sheets to maximize the enclosed volume. The fusing c ...

Association for Computing Machinery (ACM)2024

Influence of model uncertainty and long term deformations in action effects calculation in reinforced concrete structures

Xhemsi Malja

Most codes of practice adopt a semi probabilistic design approach for the dimensioning and assessment of structures. Accordingly, structural safety is ensured by performing limit state verifications using design values determined with adequately calibrated ...

EPFL2024

Insights from an extensive triaxial testing campaign on a shale for comparative site characterization of a deep geological repository

Lyesse Laloui, Alessio Ferrari, Eleonora Crisci

Several boreholes were drilled for site comparison of a deep geological repository (DGR) in Northern Switzerland. The main target of the exploration program was the >100m thick Opalinus Clay, the designated host rock encountered at approximately 450 to 100 ...

Elsevier2024

Modeling friction and wear using an adaptive discrete-continuum coupling

Manon Eugénie Voisin--Leprince

When two objects slide against each other, wear and friction occur at their interface. The accumulation of wear forms what is commonly referred to as a ``third-body''. Understanding third-body evolution has significant applications in industry, where contr ...

EPFL2024

Morphological and Material Programability of a Hall-Effect Based Soft Tactile Sensors

Josephine Anna Eleanor Hughes, Sudong Lee

The different receptors in human skin show not only diversity in the stimuli to which they respond, but also variable sensitivity and directionality. This is often determined by their location or morphology, and can play an important role in filtering or a ...

IEEE2024

How are cells instructed to form somite boundaries by the zebrafish segmentation clock?

Olivier François Venzin

In vertebrate embryos, the elongating body axis is patterned via the sequential and rhyth-mic production of segments from a posterior unsegmented tissue called the presomitic mesoderm (PSM). This process is controlled by a population of cellular oscillator ...

EPFL2023

Revealing the complexity of ultra-soft hydrogel re-swelling inside the brain

Olivier Didier Christian Rizzo, Stéphanie Lacour, John Martin Kolinski, Outman Akouissi, Michael Shur

The brain is an ultra-soft viscoelastic matrix. Sub-kPa hydrogels match the brain's mechanical properties but are challenging to manipulate in an implantable format. We propose a simple fabrication and processing sequence, consisting of de-hydration, patte ...

2023

Development of a Robotic Microsurgeon for Embryonic Research

Ece Özelçi

Understanding how biological matter takes its shape is instrumental to biology, bioengineering, medicine, and bioinspired engineering. Gaining information on the principles of morphogenesis could enable clinicians to correct developmental abnormalities, ev ...

EPFL2023

The hunt for the Karman 'constant' revisited

Peter Monkewitz

The log law of the wall, joining the inner, near-wall mean velocity profile (MVP) in wall-bounded turbulent flows to the outer region, has been a permanent fixture of turbulence research for over hundred years, but there is still no general agreement on th ...

Cambridge University Press2023

Homogenization theory captures macroscopic flow discontinuities across Janus membranes

Kevin Wittkowski, François Gallaire, Pier Giuseppe Ledda, Giuseppe Antonio Zampogna

Janus membranes, thin permeable structures with chemical and geometrical asymmetric properties, show great potential in industrial separation processes. Yet the link between the micro- and macro-scale behaviours of these membranes needs to be established r ...

Cambridge University Press2023

Atomic-scale Characterization of Strain and Gate effects on Two-dimensional Materials by Scanning Tunneling Microscopy

Jz -Yuan Juo

Strain is an inevitable phenomenon in two-dimensional (2D) material, regardless of whether the film is suspended or supported. Moreover, strain is known to alter the physical and chemical properties, such as the band gap, charge carrier effective masses, d ...

EPFL2023

Experimental testing and structural analysis of composite tile – reinforced concrete domes

Savvas Saloustros

Conventional formworks for concrete curved shells either are expensive, complex and wasteful or have formal restrictions. Using tile vaults (also known as timbrel, Guastavino, thin-tile or Catalan vaults) as stay-in-place formwork for concrete shells could ...

2023

Heterogeneity and developmental dynamics of mammalian neocortical progenitors

Leila Haj Abdullah Alieh, Gioele La Manno, Antonio Herrera Camacho

The central nervous system develops from a pool of neural progenitors which, depending on their location and time of division, generate cells committed to differentiate into specific kinds of neurons or glia. In the last decades, the developmental neurobio ...

Elsevier2023

Reaction wavefront theory of notochord segment patterning

Andrew Charles Oates

The vertebrate axis is segmented into repetitive structures, the vertebrae. In fish, these segmented structures are thought to form from the paraxial mesoderm and the adjacent notochord. Recent work revealed an autonomous patterning mechanism in the zebraf ...

FRONTIERS MEDIA SA2022

Peeling in electroadhesion soft grippers

Herbert Shea, Vito Cacucciolo

Electroadhesion endows robots with super-human abilities: mechanical geckoes that climb vertical walls and soft grippers that grasp the most delicate objects. Based on electrostatics, the adhesion forces are turned on and off by an electrical signal, promi ...

ELSEVIER2022

In vitro endoderm emergence and self-organisation in the absence of extraembryonic tissues and embryonic architecture

Stefano Davide Vianello

In humans, mice, and other mammals key internal organs such as the gut, the lungs, the pancreas, and the liver all derive from the same embryonic tissue: the endoderm. The development of all of these structures thus depends on a same set of early cells, an ...

EPFL2022

Method for labelling a device and devices obtanaible therefrom

Florian Dylan Fallegger, Nicolas Vachicouras, Ludovic Serex, Benoit Rémi Dominique Huguet

Disclosed herein is a method for labelling a portion of a device, said method comprising the steps of providing a first substrate layer of a transparent or translucent material, depositing a first coloured material onto said first substrate layer in a labe ...

2022