Modeling and Control for the Treatment of Type 1 Diabetes : An Approach Based on Therapy Parameters

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Background: Disturbances of glycemic control and large glycemic variability have been associated with increased risk of type 2 diabetes in the general population as well as complications in people with diabetes. Long-term health benefits of physical activi ...

Rapid urbanization is increasing the demand for public transport in Switzerland’s major cities. The new m3 metro line in Lausanne is planned to circulate by 2030. Its construction will require a modification of the underground flow section of the Flon Rive ...

Background Impaired heart rate variability (HRV) is associated with increased mortality in sinus rhythm. However, HRV has not been systematically assessed in patients with atrial fibrillation (AF). We hypothesized that parameters of HRV may be predictive o ...

Recent studies showed that the carotid sinus nerve (CSN) and the sympathetic nervous system (SNS) are overactivated in type 2 diabetes and that restoring the correct CSN neural activity can re-establish the proper metabolism. However, a robust characteriza ...

Cruising-for-parking constraints mobility in urban networks. Car-users may have to cruise for on-street parking before reaching their destinations. The accessibility and the cost of parking significantly influence people's travel behavior (such as mode cho ...

New advancements in the management of type I diabetic patients (T1DM) call for a new generation of monitoring systems based upon an array of metabolic biosensors including sensors for insulin detection. Blood insulin values are always less than 270 pM; the ...

The pancreas plays a central role in metabolism. The exocrine pancreas, composed of ductal and acinar cells, secretes and delivers digestive enzymes into the duodenum where they contribute to food digestion. The endocrine pancreas, constituted by the islet ...

The effect of hyperosmolarity on transient recombinant protein production in Chinese hamster ovary (CHO) cells was investigated. Addition of 90 mM NaCl to the production medium ProCHO5 increased the volumetric yield of recombinant antibody up to 4-fold rel ...

Aims/hypothesis Structural and functional imaging of the islets of Langerhans and the insulin-secreting beta cells represents a significant challenge and a long-lasting objective in diabetes research. In vivo microscopy offers a valuable insight into beta ...

Lignocellulosic biomass is considered as one of the most promising feedstocks for producing fuel ethanol because of its global availability and environmental benefits of its use. In this paper, the process of lignocellulosic ethanol production was investig ...

Modeling and simulation can be powerful tools for analyzing multi-agent systems, such as networked robotic systems and sensor networks. In this paper, it is shown concretely how instances of both these elements fit into a general methodology for multi-leve ...

Modeling and Control for the Treatment of Type 1 Diabetes : An Approach Based on Therapy Parameters

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Associations Between Device-Measured Physical Activity and Glycemic Control and Variability Indices Under Free-Living Conditions

Underground flow section modification below the new m3 Flon metro station in Lausanne

Heart Rate Variability Triangular Index as a Predictor of Cardiovascular Mortality in Patients With Atrial Fibrillation

Decoding Neural Metabolic Markers From the Carotid Sinus Nerve in a Type 2 Diabetes Model

Modeling and optimization of multimodal urban networks with limited parking and dynamic pricing

Comparative Performance of Different Nanostructured Electrochemical Sensors on Insulin Detection

Definition of in Vitro Microenvironments to Characterize and Control Pancreatic Progenitor Expansion and Differentiation

Hyperosmolarity enhances transient recombinant protein yield in Chinese hamster ovary cells

In vivo imaging of murine endocrine islets of Langerhans with extended-focus optical coherence microscopy

Process modeling and integration of fuel ethanol production from lignocellulosic biomass based on double acid hydrolysis

Toward Multi-Level Modeling of Robotic Sensor Networks: A Case Study in Acoustic Event Monitoring