Publications associées à In silico assessment of the HPLC-UV response coefficients

Analytical Engines With Context-Rich Processing: Towards Efficient Next-Generation Analytics

As modern data pipelines continue to collect, produce, and store a variety of data formats, extracting and combining value from traditional and context-rich sources such as strings, text, video, audio, and logs becomes a manual process where such formats a ...

2023

Algorithms push forward the application of MALDI-TOF mass fingerprinting in rapid precise diagnosis

Hubert Girault, Yingdi Zhu

Macromolecular mass fingerprinting using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry is a quick tool for biochemical analysis. In combination with algorithms for automated data analysis and interpretation, it has wide appli ...

WILEY2023

Analytic modelling of passive microfluidic mixers

Christophe Lallement, Jean-Michel Sallese

This paper deals with a new analytical model for microfluidic passive mixers. Two common approaches already exist for such a purpose. On the one hand, the resolution of the advection-diffusion-reaction equation (ADRE) is the first one and the closest to ph ...

AMER INST MATHEMATICAL SCIENCES-AIMS2022

High-Throughput Nanopore Fabrication and Classification Using Xe-Ion Irradiation and Automated Pore-Edge Analysis

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Large-area nanopore drilling is a major bottleneck in state-of-the-art nanoporous 2D membrane fabrication protocols. In addition, high-quality structural and statistical descriptions of as-fabricated porous membranes are key to predicting the corresponding ...

AMER CHEMICAL SOC2022

Resolving the charging paradox of neat oil droplets in water

Sergey Kulik

The thesis covers the series of questions regarding the molecular structure and charge of oil nanodroplets in water. This work proposes a mechanism responsible for the stabilization of oil nanodroplets in water, which does not involve OH- adsorption. First ...

EPFL2022

Proof-of-concept analytical instrument for label-free optical deconvolution of protein species in a mixture

Gabriel Aeppli

The adoption of process analytical technologies by the biopharmaceutical industry can reduce the cost of therapeutic drugs and facilitate investigation of new bioprocesses. Control of critical process parameters to retain critical product quality attribute ...

ELSEVIER2021

Integration of microfluidics and multimodal optics for translational bioanalytics

Daniel Migliozzi

Numerous analytical techniques for life sciences have been at the basis of the improvement of medical diagnostics and treatments. Current challenges in bioanalytics are related to the conception of methods enabling large amount of information to be extract ...

EPFL2019

Analysis and Removal of Product Gas Contaminants Present in Gasification Processes

Sven Philip Edinger

Energy demand and economic development are intrinsically linked. Earlier economic development came at the price of serious environmental pollution, posing a risk to life on earth. Thus, a transition from fossil to renewable energy is needed. Among the rene ...

EPFL2017

Efficient Online Processing for Advanced Analytics

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With the advent of emerging technologies and the Internet of Things, the importance of online data analytics has become more pronounced. Businesses and companies are adopting approaches that provide responsive analytics to stay competitive in the global ma ...

EPFL2017

Distributed Time Series Analytics

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In recent years time series data has become ubiquitous thanks to affordable sensors and advances in embedded technology. Large amount of time-series data are continuously produced in a wide spectrum of applications, such as sensor networks, medical monitor ...

EPFL2017

Runtime Prediction for Scale-Out Data Analytics

Adrian Daniel Popescu

Many analytics applications generate mixed workloads, i.e., workloads comprised of analytical tasks with different processing characteristics including data pre-processing, SQL, and iterative machine learning algorithms. Examples of such mixed workloads ca ...

EPFL2015

Fourier transform mass spectrometry at the uncertainty principle limit for improved qualitative and quantitative molecular analyses

Anton Kozhinov

Nowadays, among the instrumentation park of mass spectrometry, Fourier transform mass spectrometers (FTMS), including ion cyclotron resonance (ICR) and Orbitrap FTMS, provide the highest analytical performance for accurate measurements and mass resolution. ...

EPFL2015

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Natalia Gasilova

Fundamental biological and biochemical studies, proteomics, practical nutrition-related and medical applications, all the research fields, where bioanalytical chemistry is an essential tool, constantly require the improvement of existing techniques of bioa ...

EPFL2014

Optofluidic-tunable color filters and spectroscopy based on liquid-crystal microflows

Julien Cuennet, Demetri Psaltis, Andreas Vasdekis

The integration of color filters with microfluidics has attracted substantial attention in recent years, for on-chip absorption, fluorescence, or Raman analysis. We describe such tunable filters based on the micro-flow of liquid crystals. The filter operat ...

Royal Society of Chemistry2013

Reusable plasmonic substrates fabricated by interference lithography: a platform for systematic sensing studies

Olivier Martin, Thomas Gerd Siegfried

Surface-enhanced Raman scattering (SERS) has become increasingly popular in the scientific and industrial communities because of its analytical capabilities and potential to study fundamentals in plasmonics. Although under certain conditions extremely high ...

Wiley-Blackwell2013

Scaling up analytical queries with column-stores

Anastasia Ailamaki, Manoussos Gavriil Athanassoulis, Ioannis Alagiannis

As data analytics is used by an increasing number of applications, data analytics engines are required to execute workloads with increased concurrency, i.e., an increasing number of clients submitting queries. Data management systems designed for data anal ...

2013

Optofluidic differential spectroscopy for absorbance detection of sub-nanolitre liquid samples

Wuzhou Song, Jianhang Yang

We present a novel optofluidic differential method for carrying out absorbance spectroscopy of subnanolitre volumes of liquid samples on a microfluidic chip. Due to the reduction of liquid volume, the absorbance detection in microfluidics is often hindered ...

Royal Society of Chemistry2012

Integrated Microfluidic Liquid-Liquid Extraction for Cocaine Detection in Human Saliva

Philip Wägli

On-site drug testing using easily accessible body fluids, such as saliva, has gained a lot of importance both for road safety and forensic applications. However, saliva is a complex, inhomogeneous amalgam with many different compounds, whose concentrations ...

EPFL2012

Development of Elastomeric Optofluidic Devices for Lasing and Sensing

Wuzhou Song

The term of optofluidics defines an emergent research field that combines microfluidics and optics. In many lab-on-a-chip applications, these two technologies are used in combining the microfluidics for sample delivery and optics for sensing and controllin ...

EPFL2012

Optical Trapping in Microfluidic Channels for Functional and Chemical Analysis of Single Cells

Michael Werner

The physiological properties of cells are typically investigated in ensembles yielding averaged data that mask heterogeneities present in any cell population. Single-cell analysis techniques based on microfluidic "lab on a chip" (LOC) devices have recently ...

EPFL2011