The application of Personal Comfort Systems (PCS) in the buildings demonstrated their potential to improve thermal comfort and reduce energy use by the space conditioning HVAC systems. With its personal controllability (on-demand) PCS is a practical soluti ...
Thermal comfort and discomfort based on the local sensation of different body parts have been an important development in thermal comfort studies from the past decade. The human thermophysiology model can be a handy tool to predict local skin and core temp ...
The use of daylight in buildings is important because it contributes to energy savings by reducing the use of electric lighting and space heating. It also impacts on biological functions and on well-being. Indeed, light not only allows vision, but has non- ...
Ray et al. (Reports, 14 February 2020, p. 800) recently claimed temperature-compensated, free-running mRNA oscillations in Bmal1(-/-) liver slices and skin fibroblasts. We reanalyzed these data and found far fewer reproducible mRNA oscillations in this gen ...
American Association for the Advancement of Science2021
The mammalian liver is a central hub for systemic metabolic homeostasis. Liver tissue is spatially structured, with hepatocytes operating in repeating lobules, and sub-lobule zones performing distinct functions. The liver is also subject to extensive tempo ...
Gene expression in eukaryotes is a complex multi-step process. It starts in the nucleus with transcription, the synthesis of a mRNA copy from a DNA template. While in the nucleus, the RNA transcript is subject to multiple co- and post-transcriptional modif ...
