Publications associées à Mechanical Characterisation of Porcine Urethra: Non Linear Constitutive Models and Experimental Approach

Publications associées (27)

Idiopathic normal pressure hydrocephalus: A sulcal morphometry approach to brain phenotype and clinical response

Dimitri Nestor Alice Van De Ville, Alessandra Griffa

Idiopathic normal pressure hydrocephalus (iNPH), the leading cause of reversible dementia in older adults, is characterized by urinary incontinence, gait impairment, cognitive decline, and ventriculomegaly. Neuroradiological features rely on visual assessm ...

Elsevier BV2025

An artificial urinary sphincter based on dielectric elastomer technology

Sloan Zammouri, Yves Perriard, Yoan René Cyrille Civet, Stefania Maria Aliki Konstantinidi, Amine Benouhiba, Quentin Philippe Mario De Menech

Urinary incontinence (UI) is prevalent and distressing medical condition affecting millions of patients worldwide. Current treatment options for severe cases often involve surgical intervention, such as the implantation of an artificial urinary sphincter ( ...

Society of Photo-Optical Instrumentation Engineers (SPIE)2024

System for micturition control in a mammal with bladder disfunction

Grégoire Courtine, Jocelyne Bloch, Jordan Squair, Loïs Thomas Romain Mahe

The present invention relates to a neuromodulation/neurostimulation system (10) for stimulating at least one neuronal circuitry responsible for micturition control in a mammal with bladder disfunction, especially for bladder relaxation and/or for bladder v ...

2024

Designing for Intimate Wellbeing: Aidee, a Qualitative Approach To Urine Home Monitoring

Nicolas Henchoz, Delphine Ribes Lemay, Emily Clare Groves, Sebastian Eduardo Baez Lugo, Margherita Motta

Despite the widespread use of self-tracking technologies for promoting personal wellbeing, there is limited research on the monitoring of intimate data, particularly urine. To shed light on the design possibilities within this unexplored domain we designed ...

DRS Digital Library2024

Decoding bladder state from pudendal intraneural signals in pigs

Silvestro Micera, Stéphanie Lacour, Ivo Strauss, Valentina Marie Paggi, Leonardo Pollina

Neuroprosthetic devices used for the treatment of lower urinary tract dysfunction, such as incontinence or urinary retention, apply a pre-set continuous, open-loop stimulation paradigm, which can cause voiding dysfunctions due to neural adaptation. In the ...

2023

Microtissue models for studying the dynamics of host-pathogen interactions in the urinary bladder

Kunal Sharma

Urinary tract infections (UTIs) are amongst the most common bacterial infections and are the second-most frequent reason for antibiotic prescriptions. Moreover, in about 25% of all treated cases, recurrence of infection occurs. Uropathogenic Escherichia co ...

EPFL2021

Dynamic persistence of UPEC intracellular bacterial communities in a human bladder-chip model of urinary tract infection

Graham Knott, John McKinney, Neeraj Dhar, Vivek Vijay Thacker, François Signorino-Gelo, Kunal Sharma, Thomas Marie Simonet

Uropathogenic Escherichia coli (UPEC) proliferate within superficial bladder umbrella cells to form intracellular bacterial communities (IBCs) during early stages of urinary tract infections. However, the dynamic responses of IBCs to host stresses and anti ...

2021

Microdevices for Locomotion in Complex Biological Fluids

Tian Qiu

Locomotion is an essential feature for survival of many organisms, and it is also a technical requirement for untethered biomedical microdevices to operate inside the human body for targeted drug delivery and minimally invasive surgery. The overall goal of ...

EPFL2016

IGF-1-containing multi-layered collagen-fibrin hybrid scaffolds for bladder tissue engineering

Jeffrey Alan Hubbell, Peter Frey, Hans Mattias Larsson, Priscilla Suhasna Maithili Briquez, Elif Vardar

Clinical success of bladder reconstructive procedures could be promoted by the availability of functional biomaterials. In this study, we have developed a multi-layered scaffold consisting of a bioactive fibrin layer laminated between two collagen sheets a ...

Elsevier Sci Ltd2016

Tubular Compressed Collagen Scaffolds for Ureteral Tissue Engineering in a Flow Bioreactor System

Jeffrey Alan Hubbell, Peter Frey, Hans Mattias Larsson, Elif Vardar

Ureteral replacement by tissue engineering might become necessary following tissue loss after excessive ureteral trauma, after retroperitoneal cancer, or even after failed reconstructive surgery. This need has driven innovation in the design of novel scaff ...

Mary Ann Liebert, Inc2015

Neural circuits of idiopathic Normal Pressure Hydrocephalus: A perspective review of brain connectivity and symptoms meta-analysis

Dimitri Nestor Alice Van De Ville, Alessandra Griffa

Idiopathic normal pressure hydrocephalus (iNPH) is a prevalent reversible neurological disorder characterized by impaired locomotion, cognition and urinary control with ventriculomegaly. Symptoms can be relieved with cerebrospinal fluid drainage, which mak ...

PERGAMON-ELSEVIER SCIENCE LTD2020

Is There a Need for Smooth Muscle Cell Transplantation in Urethral Reconstruction?

Peter Frey

Background: Hypospadias and urethral strictures are conditions requiring additional tissue for reconstruction. Due to a limited source of tissue, autologous skin and oral mucosa are frequently used. However, long-term follow-up studies demonstrated signifi ...

Mary Ann Liebert, Inc2014

Biodegradation and Antimicrobial Properties of Zinc Oxide-Polymer Composite Materials for Urinary Stent Applications

Lorenzo Lucherini

Research advancements in the field of urinary stents have mainly been in the selection of materials and coatings to address commonly faced problems of encrustation and bacterial adhesion. In this study, polylactic acid (PLA) and polypropylene (PP) were eva ...

2020

A Microchannel Neuroprosthesis for Bladder Control After Spinal Cord Injury in Rat

Stéphanie Lacour, Ivan Rusev Minev, Katherine Marie Musick

A severe complication of spinal cord injury is loss of bladder function (neurogenic bladder), which is characterized by loss of bladder sensation and voluntary control of micturition (urination), and spontaneous hyperreflexive voiding against a closed sphi ...

American Association for the Advancement of Science2013

Urine-Contactless Device to Empty Bladders: an Ex-Vivo Proof-of-Concept Study in Porcine Bladders

Yves Perriard, Yoan René Cyrille Civet, Francesco Clavica

Current treatments for underactive bladder (UAB) have negative side effects, such as urinary tract infections, mainly because devices used for bladder emptying are in direct contact with urine (e.g. permanent or intermittent catheterisation). Moreover, mos ...

Wiley2019

Culture and Characterization of Human and Porcine Urothelial Progenitor Cells

Hans Mattias Larsson

An estimated 400 million people worldwide suffer from bladder diseases. However, little is known at the cellular level as to what causes or initiates many of these diseases. Therefore, this thesis has focused on understanding one cell type within the bladd ...

EPFL2012

Development of a biologically inspired in-vitro platform for long-term assessment of commercial and innovative ureteral stents

Yves Perriard, Yoan René Cyrille Civet, Francesco Clavica

Ureteral stents are small flexible tubes which are clinically used to restore the urine drainage in presence of obstructions of the ureteral lumen such as tumours, kidney/ureteral stones. The lifetime risk of developing urinary stones is about 20% in men a ...

2019

In-vivo performance of high-density collagen gel tubes for urethral regeneration in a rabbit model

Jeffrey Alan Hubbell, Peter Frey

Congenital malformations or injuries of the urethra can be treated using existing autologous tissue, but these procedures are sometimes associated with severe complications. Therefore, tissue engineering may be advantageous for generating urethral grafts. ...

Elsevier2012

Impedance pumping as a non-invasive treatment for underactive bladder? An ex-vivo proof-of-concept-study in porcine bladders

Yves Perriard, Yoan René Cyrille Civet, Francesco Clavica

In patients suffering from underactive bladder (UAB), the contraction of the detrusor muscle has insufficient strength or duration to ensure efficient bladder emptying. Although catheterisation is currently the most effective method to empty the bladder, i ...

2019

A bioactive injectable bulking material; a potential therapeutic approach for stress urinary incontinence

Jeffrey Alan Hubbell, Matthias Lütolf, Peter Frey, Hans Mattias Larsson, Elif Vardar

Stress urinary incontinence (SUI) is a life changing condition, affecting 20 million women worldwide. In this study, we developed a bioactive, injectable bulking agent that consists of Permacol (TM) (Medtronic, Switzerland) and recombinant insulin like gro ...

ELSEVIER SCI LTD2019