Publications associées à Optical Urea Sensing in Sweat for Kidney Healthcare by Sensitive and Selective Non-enhanced Raman Spectroscopy

Multisensing wearables for real-time monitoring of sweat electrolyte biomarkers during exercise and analysis on their correlation with core body temperature

Danick Briand, Silvia Demuru, Brince Paul Kunnel, Jaemin Kim, Vincent Gremeaux, Shu Wang

Sweat secreted by the human eccrine sweat glands can provide valuable biomarker information during exercise. Real-time non-invasive biomarker recordings are therefore useful for evaluating the physiological conditions of an athlete such as their hydration ...

2023

Configurable Organic Electrochemical Transistors with Printed Functional Materials for Multiplexed Sweat Analysis

Silvia Demuru

Monitoring human sweat with wearable biochemical sensors could give insights into the hydration, fatigue, and health status, tracking the variations of biomarkers non-invasively and in real-time. In this field, organic electrochemical transistors (OECTs) a ...

EPFL2022

Dynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression

Ming Yang, Vassily Hatzimanikatis, Maria Masid Barcon

Metabolic reprogramming is critical for tumor initiation and progression. However, the exact impact of specific metabolic changes on cancer progression is poorly understood. Here, we integrate multimodal analyses of primary and metastatic clonally-related ...

Nature Portfolio2022

Wearable systems for measuring sweat rate and methods of using the same

Fabien Patrick Wildhaber, Hoël Maxime Guérin, Junrui Zhang

Presented herein are systems and methods for measuring sweat rate of a subject using a wearable system. A sweat rate may be determined automatically based on one or more signals produced by a wetting sensor module in response to a presence of sweat in the ...

2021

Printed Iontophoretic‐Integrated Wearable Microfluidic Sweat‐Sensing Patch for On‐Demand Point‐Of‐Care Sweat Analysis

Danick Briand, Silvia Demuru, Brince Paul Kunnel

In recent years, wearable epidermal sweat sensors have received extensive attention owing to their great potential to provide personalized information on the health status of individuals at the molecular level. For on‐demand medical analysis of sweat in se ...

Wiley2021

A Wearable Autonomous Colorimetric Sweat Induction System for Sweat Analysis

Silvia Demuru, Brince Paul Kunnel

The wearable biochemical sweat sensor's capability to provide insight into molecular information of health dynamics ignites sweat analysis as a promising noninvasive diagnosis scheme for precision medicine. Here, we demonstrate, for the first time, a color ...

IEEE2021

Microfluidics by Additive Manufacturing for Wearable Biosensors: A Review

Christian Enz, Sandro Carrara, Mahshid Alsadat Padash

Wearable devices are nowadays at the edge-front in both academic research as well as in industry, and several wearable devices have been already introduced in the market. One of the most recent advancements in wearable technologies for biosensing is in the ...

2020

Sweat monitoring with CMOS compatible technology: ISFETS and beyond

Francesco Bellando

In recent years, sweat has gained increasing attention from the scientific community as a new analyte for health monitoring. The main advantage with respect to the "Gold Standard" for laboratory analysis, i.e. blood, is of course the possibility of perform ...

EPFL2020

Electrochemical determination of nicotine in smokers' sweat

Sandro Carrara, Tugba Kilic

In this work, we report the demonstration of the capability of electrochemical sensors to provide measurements directly on the sweat of volunteers to successfully discriminate heavy smokers by light ones. Since its importance as pharmaceutical treatment-ag ...

ELSEVIER2020

A 3D printed wearable device for sweat analysis

Sandro Carrara, Mahshid Alsadat Padash

This work presents a wearable microfluidic device for sweat analysis. The purpose of this device is to collect sweat from the skin and convey it to the sensor. The device is printed by a 3D printer with Multi-Jet Modelling (MJM) technology using flexible m ...

IEEE2020

Wearable System for Real-Time Sensing of Biomarkers in Human Sweat

Junrui Zhang

Wearable sweat sensing systems offer non-invasive and real-time bio-data streaming solutions. They open the possibility for continuous monitoring of biomarkers' concentrations as well as their variation in sweat, which is a complementary to current passive ...

EPFL2019

Wearable System with Integrated Passive Microfluidics for Real-Time Electrolyte Sensing in Human Sweat

Erick Antonio Garcia Cordero

Wearable systems embodied as patches could offer noninvasive and real-time solutions for monitoring of biomarkers in human sweat as an alternative to blood testing, with applications in personalized and preventive healthcare. Sweat is considered to be a bi ...

EPFL2018

Effect of Chaotropes on the Transfer of Ions and Dyes across the Liquid–Liquid Interface

Hubert Girault, Grégoire Clément Gschwend, Pekka Eero Peljo, Evgeny Smirnov, Lucie Josette Renée Rivier, Elena Vladimirova

Chaotropes such as urea can break the structure of water, weakening the hydrophobic effect and reducing aggregation. Here, we investigated how the addition of urea affects the transfer of ions and cationic dyes across the interface between immiscible elect ...

2018

Lab on skin™: 3D monolithically integrated zero-energy micro/nanofludics and FD SOI ion sensitive FETs for wearable multi-sensing sweat applications

Mihai Adrian Ionescu, Fabien Patrick Wildhaber, Johan Frédéric Longo, Hoël Maxime Guérin, Erick Antonio Garcia Cordero, Francesco Bellando

This paper reports a novel fully integrated low power multi-sensing smart system, which, by wafer-level 3D heterogeneous integration of Ion Sensitive Fully Depleted (FD) FETs and SU-8 micro/nanofludics, achieves the first of its kind wearable multi-sensing ...

2017

Renal Fanconi Syndrome and Hypophosphatemic Rickets in the Absence of Xenotropic and Polytropic Retroviral Receptor in the Nephron

Dmitri Firsov, Vladimir Katanaev

Tight control of extracellular and intracellular inorganic phosphate (Pi) levels is critical to most biochemical and physiologic processes. Urinary Pi is freely filtered at the kidney glomerulus and is reabsorbed in the renal tubule by the action of the ap ...

Amer Soc Nephrology2017