Effect of Medication and Freezing of Gait on Rambling and Trembling in Quiet Standing in Individuals With Parkinson's Disease

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Proprioception is essential for perception and action. Like any other sense, proprioception is also subject to illusions. In this study, we model classic proprioceptive illusions in which tendon vibrations lead to biases in estimating the state of the body ...

Proprioception tells the brain the state of the body based on distributed sensory neurons. Yet, the principles that govern proprioceptive processing are poorly understood. Here, we employ a task -driven modeling approach to investigate the neural code of p ...

The function of the neocortex is fundamentally determined by its repeating microcircuit motif, but also by its rich, hierarchical, interregional structure with a highly specific laminar architecture. The last decade has seen the emergence of extensive new ...

Digital brain atlases define a hierarchy of brain regions and their locations in three-dimensional space. They provide a standard coordinate system in which diverse datasets can be integrated for visualization and analysis. They also enable building of dat ...

Neuroprostheses have been used clinically for decades, to help restore or preserve brain functions, when pharmaceutical treatments are inefficient. Although great progress in the field has been made over the years to interface with the nervous system, surf ...

Ambiguous sensory information can lead to spontaneous alternations between perceptual states, recently shown to extend to tactile perception. The authors recently proposed a simplified form of tactile rivalry which evokes two competing percepts for a fixed ...

The exact somatotopy of the human facial representation in the primary somatosensory cortex (S1) remains de-bated. One reason that progress has been hampered is due to the methodological challenge of how to apply automated vibrotactile stimuli to face area ...

The peripheral nervous system (PNS) regulates the exchange of sensory information and motor commands between the body and the central nervous system. Further, through the autonomic nervous system, the PNS plays a pivotal role in controlling vital physiolog ...

Pre-stimulus alpha (α) activity can influence perception of shortly presented, low-contrast stimuli. The underlying mechanisms are often thought to affect perception exactly at the time of presentation. In addition, it is suggested that α cycles determine ...

Out-of-body experiences (OBEs) are characterized by the subjective feeling of being located outside one's physical body and perceiving one's own body from an elevated perspective looking downwards. OBEs have been correlated with abnormal integration of bod ...

Rodents depend on olfaction and touch to meet many of their fundamental needs. However, the impact of simultaneous olfactory and tactile inputs on sensory representations in the cortex remains elusive. To study these interactions, we recorded large populat ...

We present an approach for tracking fast spatiotemporal cortical dynamics in which we combine white matter connectivity data with source-projected electroencephalographic (EEG) data. We employ the mathematical framework of graph signal processing in order ...

Recent research highlights the overwhelming role of vestibular information for higher order cognition. Central to body perception, vestibular cues provide information about self-location in space, self-motion versus object motion, and modulate the percepti ...

Recent studies have highlighted the role of multisensory integration as a key mechanism of self-consciousness. In particular, integration of bodily signals within the peripersonal space (PPS) underlies the experience of the self in a body we own (self-iden ...

The skin is not only the largest human organ, capable of accomplishing distributed and multimodal sensing functions. Replicating the versatility of skin artificially is a significant challenge, not only in terms of signal processing but also in mechanics. ...

In non-human primates several brain areas contain neurons that respond to both vestibular and somatosensory stimulation. In humans, vestibular stimulation activates several somatosensory brain regions and improves tactile perception. However, less is known ...

Our brain continuously self-organizes to construct and maintain an internal representation of the world based on the information arriving through sensory stimuli. Remarkably, cortical areas related to different sensory modalities appear to share the same f ...

Frontal cortex plays a central role in the control of voluntary movements, which are typically guided by sensory input. Here, we investigate the function of mouse whisker primary motor cortex (wM1), a frontal region defined by dense innervation from whiske ...

Effect of Medication and Freezing of Gait on Rambling and Trembling in Quiet Standing in Individuals With Parkinson's Disease

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Deep-learning models of the ascending proprioceptive pathway are subject to illusions

Task-driven neural network models predict neural dynamics of proprioception

Modeling and Simulation of Neocortical Micro- and Mesocircuitry. Part I: Anatomy

Enhancement of brain atlases with region-specific coordinate systems: flatmaps and barrel column annotations

Unraveling behavior and cortical signals to guide the development of soft neuroprostheses for auditory restoration and spreading depolarization

Hierarchical processing underpins competition in tactile perceptual bistability

Hand and face somatotopy shown using MRI-safe vibrotactile stimulation with a novel soft pneumatic actuator (SPA)-skin interface

Soft bioelectronic technologies for selective and multimodal peripheral nerve interfaces

Pre-stimulus alpha activity modulates long-lasting unconscious feature integration

Out-of-body illusion induced by visual-vestibular stimulation

Olfactory modulation of barrel cortex activity during active whisking and passive whisker stimulation

Connectome spectral analysis to track EEG task dynamics on a subsecond scale

Differential effects of vestibular processing on orienting exogenous and endogenous covert visual attention

Unconscious integration of multisensory bodily inputs in the peripersonal space shapes bodily self-consciousness

Stretchable metallization technologies for skin-like transducers

Distinct vestibular effects on early and late somatosensory cortical processing in humans

Theory of representation learning in cortical neural networks

Movement Initiation Signals in Mouse Whisker Motor Cortex