Optimized office lighting advances melatonin phase and peripheral heat loss prior bedtime

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Objective: Isolated rapid eye movement (REM) sleep behavior disorder (iRBD) is, in most cases, an early stage of Parkinson's disease or related disorders. Diagnosis requires an overnight video-polysomnogram (vPSG), however, even for sleep experts, interpre ...

In an era where portable electronic devices are indispensable for a wide range of activities, the need for displays that provide both long-lasting battery life and excellent visibility in different lighting conditions is increasingly important. Emissive di ...

The synchronization of circadian clock depends on a central pacemaker located in the suprachiasmatic nuclei. However, the potential feedback of peripheral signals on the central clock remains poorly characterized. To explore whether peripheral organ circad ...

Wearable biosensors and smartphone applications can measure physiological variables over multiple days in free-living conditions. We measure food and drink ingestion, glucose dynamics, physical activity, heart rate (HR), and heart rate variability (HRV) in ...

Earth rotation around its axis imposes a 24-hour rhythmicity to all life on the planet. Rather than passively responding to these periodic changes, nature has given us an internal timekeeper, the circadian clock, to anticipate to our advantage the fluctuat ...

Designing architectural façades that allow sufficient daylight to create visually comfortable and pleasant environments is a challenging aspect of building design. It requires accounting for visual comfort and discomfort glare risks and understanding the f ...

Nerve injuries cause permanent neurological disability due to limited axonal regeneration. Injury-dependent and-independent mechanisms have provided important insight into neuronal regeneration, however, common denominators underpinning regeneration remain ...

Complex Fenestration Systems (CFSs) can significantly impact both the visual and non-visual daylight effects on the occupants as well as the energy performance of buildings. To ensure that those impacts improve the overall situation, proper control algorit ...

The circadian clock modulates human physiology. However, the organization of tissue-specific gene expression rhythms and how these depend on age and sex is not defined in humans. We combined data from the Genotype-Tissue Expression (GTEx) project with an a ...

When studying discomfort glare, researchers tend to rely on a single questionnaire item to obtain user evaluations. It is unclear whether the choice of questionnaire item affects the distribution of user responses and leads to inconsistencies between studi ...

This work is dedicated to the systematic investigation of wind turbine wakes under the effect of pressure gradients. Wind tunnel experiments are carried out with a wind turbine positioned on straight ramps of increasing angle such that it experiences an ap ...

Efficient numerical simulations of coupled multi-component systems can be particularly challenging. This is mostly due to the complexity of their solutions, as mutual interactions may cause emergent behaviors, including synchronization and instabilities. V ...

Understanding the factors that influence the human perception of glare is necessary to properly address glare risks in buildings and achieve comfortable visual environments, especially in the workplace. Yet large inter-individual variabilities in glare per ...

This article provides a comprehensive review of the most recent advances in the planning, execution, and analysis of inflow and wake measurements from nacelle-mounted wind Doppler lidars. Lidars installed on top of wind turbines provide a holistic view of ...

Advances in computational capabilities and large volumes of experimental data have established computer simulations of brain tissue models as an important pillar in modern neuroscience. Alongside, a variety of domain specific languages (DSLs) have been dev ...

This paper presents a theoretical analysis of linear interpolation as a principled method for stabilizing (large-scale) neural network training. We argue that instabilities in the optimization process are often caused by the nonmonotonicity of the loss lan ...

Enhancing lighting conditions in institutions for individuals with dementia improves their sleep, circadian rhythms and well-being. Here, we report first findings that exposure to brighter light during daytime may support the immune response to the annual ...

The ipRGCs in the human eye mediate several effects on people, such as alertness and circadian rhythms. The spectral, temporal and spatial characteristics of light influence the magnitude of these effects. To facilitate the anticipation of the ipRGC-influe ...

With the growing awareness about ipRGC-influenced light (IIL) responses, design applications related to these responses are flourishing. To compare design options and optimize lighting conditions for building occupants, lighting simulations are typically u ...

Recent evidence suggests that circadian clocks ensure temporal orchestration of lipid homeostasis and play a role in pathophysiology of metabolic diseases in humans, including type 2 diabetes (T2D). Nevertheless, circadian regulation of lipid metabolism in ...

Optimized office lighting advances melatonin phase and peripheral heat loss prior bedtime

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Automated Detection of Isolated REM Sleep Behavior Disorder Using Computer Vision

MEMS-based Tunable Metasurface for Reflective Display Applications

Mice with humanized livers reveal the role of hepatocyte clocks in rhythmic behavior

Uncovering personalized glucose responses and circadian rhythms from multiple wearable biosensors with Bayesian dynamical modeling

Statistical physics of periodic biological processes

Discomfort glare from daylight: Influence of transmitted color and the eye's macular pigment

The circadian clock time tunes axonal regeneration

Glare analysis of an integral daylighting and lighting control strategy for offices

Sex-dimorphic and age-dependent organization of 24-hour gene expression rhythms in humans

Comparison of questionnaire items for discomfort glare studies in daylit spaces

An experimental and analytical study of wind turbine wakes under pressure gradient

Reduced order models for coupled systems

Influence of macular pigment on the sensitivity to discomfort glare from daylight

Characterization of wind turbine flow through nacelle-mounted lidars: a review

MOD2IR: High-Performance Code Generation for a Biophysically Detailed Neuronal Simulation DSL

Stable Nonconvex-Nonconcave Training via Linear Interpolation

Preliminary evidence that daily light exposure enhances the antibody response to influenza vaccination in patients with dementia

A simulation tool for building and lighting design considering ipRGC-influenced light responses

Validation of spectral simulation tools in the context of ipRGC-influenced light responses of building occupants

Type 2 diabetes disrupts circadian orchestration of lipid metabolism and membrane fluidity in human pancreatic islets