Depotentiation of associative plasticity is intact in Parkinson's disease with mild dyskinesia

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Publications associées (28)

Noninvasive deep brain stimulation to modulate human behavior by means of transcranial temporal interference electrical stimulation

Elena Beanato

All functions we use in our everyday life depend on a complex interplay between both cortical and subcortical brain areas, communicating in between each others. When a region is affected by either an accident, aging or neurodegenerative diseases, the whole ...

EPFL2023

Engram cell connectivity as a mechanism for information encoding and memory function

Maurizio Ferdinando Pezzoli

Information derived from experiences is incorporated into the brain as changes to ensembles of cells, termed engram cells, which allow memory storage and recall. The mechanism by which those changes hold specific information is unclear. Here, we test the h ...

Cell Press2023

Cortical cell assemblies and their underlying connectivity: an in silico study

Michael Reimann, András Ecker, Daniela Egas Santander, Sirio Bolaños Puchet, James Bryden Isbister

Recent developments in experimental techniques have enabled simultaneous recordings from thousands of neurons, enabling the study of functional cell assemblies. However, determining the patterns of synaptic connectivity giving rise to these assemblies rema ...

2024

Increased functional connectivity in the right dorsal auditory stream after a full year of piano training in healthy older adults

Dimitri Nestor Alice Van De Ville

Learning to play an instrument at an advanced age may help to counteract or slow down age-related cognitive decline. However, studies investigating the neural underpinnings of these effects are still scarce. One way to investigate the effects of brain plas ...

Nature Portfolio2023

Different responses of mice and rats hippocampus CA1 pyramidal neurons to in vitro and in vivo-like inputs

Maurizio Ferdinando Pezzoli, Ying Shi, Armando Romani, Michele Migliore, Rosanna Migliore

The fundamental role of any neuron within a network is to transform complex spatiotemporal synaptic input patterns into individual output spikes. These spikes, in turn, act as inputs for other neurons in the network. Neurons must execute this function acro ...

2023

Loss of Motor Cortical Inputs to the Red Nucleus after CNS Disorders in Nonhuman Primates

Simon Borgognon

The premotor (PM) and primary motor (M1) cortical areas broadcast voluntary motor commands through multiple neuronal pathways, including the corticorubral projection that reaches the red nucleus (RN). However, the respective contribution of M1 and PM to co ...

SOC NEUROSCIENCE2023

Pathway and directional specificity of Hebbian plasticity in the cortical visual motion processing network

Michele Bevilacqua, Friedhelm Christoph Hummel, Estelle Emeline Raffin

Cortico-cortical paired associative stimulation (ccPAS), which repeatedly pairs single-pulse transcranial magnetic stimulation (TMS) over two distant brain regions, is thought to modulate synaptic plasticity. We explored its spatial selectivity (pathway an ...

2023

Mechanisms Underlying the Recruitment of Inhibitory Interneurons in Fictive Swimming in Developing Xenopus laevis Tadpoles

Haoyu Zhang, Andrea Ferrario

Developing spinal circuits generate patterned motor outputs while many neurons with high membrane resistances are still maturing. In the spinal cord of hatchling frog tadpoles of unknown sex, we found that the firing reliability in swimming of inhibitory i ...

SOC NEUROSCIENCE2023

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