Parallelization of microfluidic flow-focusing devices

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Fluid flow through microcracked and fractured granitic reservoirs

Marie Estelle Solange Violay, Michael Heap, Lucille Jocelyne Nadine Carbillet

The permeability of crustal rocks and rock-masses dictates the efficiency of hydrothermal circulation and therefore the productivity of geothermal resources. In this study, we find by monitoring P-wave velocity that thermal microcracking in Lanhélin granit ...

2023

Dielectric Elastomer Actuator-Based Valveless Impedance-Driven Pumping for Meso- and Macroscale Applications

Yves Perriard, Yoan René Cyrille Civet, Thomas Guillaume Martinez, Armando Matthieu Walter, Amine Benouhiba, Francesco Clavica, Silje Ekroll Jahren

Impedance pumps are simple designs that allow the generation or amplification of flow. They are fluid-filled systems based on flexible tubing connected to tubing with different impedances. A periodic off-center compression of the flexible tubing causes the ...

2023

Acoustofluidic large-scale mixing for enhanced microfluidic immunostaining for tissue diagnostics

Martinus Adela Maria Gijs, Diego Gabriel Dupouy, Muaz Salama Abdelmonem Draz

The usage of microfluidics for automated and fast immunoassays has gained a lot of interest in the last decades. This integration comes with certain challenges, like the reconciliation of laminar flow patterns of micro-scale systems with diffusion-limited ...

ROYAL SOC CHEMISTRY2023

A fully-coupled highly-parallelized geomechanical simulator for assessing induced seismicity

Jean-François Molinari, Brice Tanguy Alphonse Lecampion, Guillaume Anciaux, Nicolas Richart, Emil Gallyamov

Induced seismicity caused by anthropogenic modification of the subsurface effective stress state has been observed in a number of industrial applications -- from hydrocarbon extraction (e.g., Groningen [1]), drilling waste-water disposal (e.g., [2]) to the ...

2023

Permeability sets the linear path instability of buoyancy-driven disks

François Gallaire, Pier Giuseppe Ledda, Giuseppe Antonio Zampogna

The prediction of trajectories of buoyancy-driven objects immersed in a viscous fluid is a key problem in fluid dynamics. Simple-shaped objects, such as disks, present a great variety of trajectories, ranging from zig-zag to tumbling and chaotic motions. Y ...

Cambridge University Press2023

Rock-Flow Cell Parameters Evaluation Using Ultrasound Doppler Velocimetry

Giovanni De Cesare

This work presents a study of two-phase flow generated inside a rock-flow cell setup. It is characterized by a pipe section filled with fluid (oil in our studies) that is put into oscillation around its mass centre by an electric motor. This type of appara ...

2023

The Effects of Spatial Organization and Fluid Flow on the Social Interactions in Microbial Communities

Jeremy Pak Hei Wong

Bacteria often engage in social interactions with neighbouring bacteria. Ecosystems which are subjected to social interactions have been widely studied in well mixed settings such as test tubes, allowing us to identify the cellular components contributing ...

EPFL2023

A Fast Hybrid Pressure-Correction Algorithm for Simulating Incompressible Flows by Projection Methods

Jiannong Fang

To enforce the conservation of mass principle, a pressure Poisson equation arises in the numerical solution of incompressible fluid flow using the pressure-based segregated algorithms such as projection methods. For unsteady flows, the pressure Poisson equ ...

2023

Microfluidic devices

Matthias Lütolf, Jisoo Park

The present disclosure relates to a microfluidic device comprising: a substrate; a culture chamber (130); a loading channel (170) in fluid communication with the culture chamber; at least one auxiliar channel (170-1, 5 170-2) extending from and in fluid co ...

2023

Biofilm morphogenesis on soft hydrogels

Alice Cont

Bacteria often colonize their environment in the form of surface attached multicellular communities called biofilms. Biofilms grow from surface-attached cells that undergo division while self-embedding in a viscoelastic matrix. Biofilms grow at the surface ...

EPFL2023

High-resolution imaging and analysis of the intestinal bacterial load of Caenorhabditis elegans during early adulthood

Martinus Adela Maria Gijs, Farzad Rezaeianaran

We study the presence within the worm Caenorhabditis elegans (C. elegans) of a fluorescent strain of the worm's bacterial food (Escherichia coli (E. coli) OP50) during early adulthood. Use of a microfluidic chip based on a thin glass coverslip substrate al ...

ROYAL SOC CHEMISTRY2023

From coating flow patterns to porous body wake dynamics via multiscale models

Pier Giuseppe Ledda

Multiscale phenomena are involved in countless problems in fluid mechanics. Coating flows are known to exhibit a broad variety of patterns, such as wine tears in a glass and dripping of fresh paint applied on a wall. Coating flows are typically modeled und ...

EPFL2022