While ventricular electromechanics is extensively studied in both physiological and pathological conditions, four-chamber heart models have only been addressed recently; most of these works however neglect atrial contraction. Indeed, as atria are character ...
Background and Objective: Event-based analog-to-digital converters allow for sparse bio-signal acquisition, enabling local sub-Nyquist sampling frequency. However, aggressive event selection can cause the loss of important bio-markers, not recoverable with ...
Amyloidosis refers to a range of medical conditions in which misshapen proteins accumulate in various organs and tissues, forming insoluble fibrils. Cardiac amyloidosis is frequently linked to the buildup of misfolded transthyretin (TTR) or immunoglobulin ...
In order to simulate the cardiac function for a patient-specific geometry, the generation of the computational mesh is crucially important. In practice, the input is typically a set of unprocessed polygonal surfaces coming either from a template geometry o ...
In this paper, we present a mathematical model able to simulate the cardiac function. We first describe the basic physical principles behind the mathematical equations, then we illustrate a few examples of application to problems of clinical relevance. ...
The monitoring of central hemodynamic parameters such as cardiac output (CO) and pulmonary artery pressure (PAP) is of paramount clinical importance to assess the health status of the cardiovascular system. However, their measurement requires the insertion ...
As part of the 2015 PhysioNet/CinC Challenge, this work aims at lowering the number of false alarms, which are a persistent concern in the intensive care unit. The multimodal database consists of 1250 life-threatening alarm recordings, each categorized as ...
Stepwise catheter ablation (step-CA) can terminate long-standing persistent atrial fibrillation (LS-pAF) within the left atrium (LA) or may require additional right atrial (RA) ablation. Intracardiac organization indices such as AF cycle length (AFCL) have ...
It was the aim of this study to investigate the long- term effects of reduced aortic compliance on cardiovascular hemodynamics and cardiac remodeling. ...
In this thesis we study ventricular-arterial coupling in rodents under the influence of arterial stiffening and myocardial infarction (MI), combination of the two considered as a novel cardiovascular research model for diseased hearts pumping against an ag ...