A new approach for identifying positional isomers of glycans cleaved from monoclonal antibodies

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While glycans are present on the surface of cells in all living organisms and play key roles in most biological processes, their isomeric complexity makes their structural characterization challenging. Of particular importance are positional isomers, for w ...

Chirality (C) is a fundamental property of objects, in terms of symmetry. It is extremely important to sense and distinguish chiral molecules in the fields of biochemistry, science, and medicine. Vibrational circular dichroism (VCD) spectroscopy, obtained ...

Mid-infrared (mid-IR) observations are powerful in identifying heavily obscured active galactic nuclei (AGN) that have weak emission in other wavelengths. Data from the Mid-Infrared Instrument (MIRI) on board the James Webb Space Telescope provides an exce ...

Glycan analysis has evolved considerably during the last decade. The advent of high-resolution ion-mobility spectrometry has enabled the separation of isomers with only the slightest of structural differences. However, the ability to separate such species ...

Integrated optics has shown itself very convenient for exploiting nonlinear processes as it results in high confinement factor, freedom of dispersion engineering and compactness. However, the choice of materials is crucial for the development of nonlinear ...

Determining the primary structure of glycans remains challenging due to their isomeric complexity. While high-resolution ion mobility spectrometry (IMS) has recently allowed distinguishing between many glycan isomers, the arrival-time distributions (ATDs) ...

Cytotherapies are often necessary for the management of symptomatic large knee (osteo)-chondral defects. While autologous chondrocyte implantation (ACI) has been clinically used for 30 years, allogeneic cells (clinical-grade FE002 primary chondroprogenitor ...

Infrared spectroscopy (IR) is a staple structural elucidation and characterization technique because of its ability to identify functional groups and its ease of use. Interestingly, it allows the capture of electronic effects via their influence on the bon ...

Infrared (IR) spectroscopy and catalysis represent two of the most practically relevant topics in chemistry, but they are normally taught in separate contexts at the undergraduate level. Although IR spectroscopy is introduced to students as a tool for orga ...

Aerosols play a significant role in the atmosphere through affecting the radiative budget, cloud condensation nuclei activity, and visibility. They also cause adverse health effects leading to premature deaths. A major fraction of aerosols is organic matte ...

Here, we present new cryogenic infrared spectra of the (Imidazole) H-n(+) (n=1,2,3) ions. The data was obtained using helium tagging infrared predissociation spectroscopy. The new results were compared with the data obtained by Gerardi et al. (Chem. Phys. ...

The structuring of mid-IR materials, such as chalcogenide glass (ChG), at the micro and nano scales, is of high interest for the fabrication of photonic devices in general, and for spectroscopy applications in particular. One efficient method for producing ...

Infrared spectroscopy provides unique information on the composition and dynamics of biochemical systems by resolving the characteristic absorption fingerprints of their constituent molecules. Based on this inherent chemical specificity and the capability ...

A new approach for identifying positional isomers of glycans cleaved from monoclonal antibodies

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Identification of N-glycan positional isomers by combining IMS and vibrational fingerprinting of structurally determinant CID fragments

Dielectric Tetramer Nanoresonators Supporting Strong Superchiral Fields for Vibrational Circular Dichroism Spectroscopy

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Identification of Mobility-Resolved N-Glycan Isomers

Hybrid lithium niobate-on-silicon nitride platform for mid-IR supercontinuum generation

A New Strategy Coupling Ion-Mobility-Selective CID and Cryogenic IR Spectroscopy to Identify Glycan Anomers

Autologous and Allogeneic Cytotherapies for Large Knee (Osteo)Chondral Defects: Manufacturing Process Benchmarking and Parallel Functional Qualification

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In Situ Infrared Spectroscopy of NOx Reduction Catalysts: A Laboratory Exercise for In-Person and Virtual Learning

Chemical characterization of organic aerosols with a focus on biomass burning and mid-infrared spectroscopy

Structures of the (Imidazole)(n)H+ ... Ar (n=1,2,3) complexes determined from IR spectroscopy and quantum chemical calculations

Ultrafast Laser Direct-Writing of Self-Organized Microstructures in Ge-Sb-S Chalcogenide Glass

Metasurface-Enhanced Infrared Spectroscopy: An Abundance of Materials and Functionalities