The Demographic and Adaptive History of the African Green Monkey

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Publications associées (30)

Mutation-Attention (MuAt): deep representation learning of somatic mutations for tumour typing and subtyping

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Background: Cancer genome sequencing enables accurate classification of tumours and tumour subtypes. However, prediction performance is still limited using exome-only sequencing and for tumour types with low somatic mutation burden such as many paediatri ...

2023

Frequent asymmetric migrations suppress natural selection in spatially structured populations

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Natural microbial populations often have complex spatial structures. This can impact their evolution, in particular the ability of mutants to take over. While mutant fixation probabilities are known to be unaffected by sufficiently symmetric structures, ev ...

Oxford Univ Press2023

In situ monitoring of femtosecond laser-induced modifications in dielectrics

Olivier Bernard

Over the last decades, the progress made in the generation of laser pulses shorter than a picosecond (10^-12 s) has allowed us to reach extreme optical power intensities exceeding 10^15 W cm^-2. This tremendous power has triggered an abundance of original ...

EPFL2023

Cellularization across eukaryotes: Conserved mechanisms and novel strategies

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Many eukaryotes form multinucleated cells during their devel-opment. Some cells persist as such during their lifetime, others choose to cleave each nucleus individually using a specialized cytokinetic process known as cellularization. What is cellula-rizat ...

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Resilient drones with morphing wings

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Winged aerial robots and Unmanned Aerial Vehicles (UAVs) commonly referred to as winged drones and drones, are increasingly used in a wide range of professional and non-professional applications today, spanning from civilian to military. As a result, they ...

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Development of a Robotic Microsurgeon for Embryonic Research

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Understanding how biological matter takes its shape is instrumental to biology, bioengineering, medicine, and bioinspired engineering. Gaining information on the principles of morphogenesis could enable clinicians to correct developmental abnormalities, ev ...

EPFL2023

Evaluation of genetic demultiplexing of single-cell sequencing data from model species

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Single-cell sequencing (sc-seq) provides a species agnostic tool to study cellular processes. However, these technologies are expensive and require sufficient cell quantities and biological replicates to avoid artifactual results. An option to address thes ...

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Genomics of Preaxostyla Flagellates Illuminates the Path Towards the Loss of Mitochondria

Marek Elias, Shweta Vinodrai Pipaliya

The notion that mitochondria cannot be lost was shattered with the report of an oxymonad Monocercomonoides exilis, the first eukaryote arguably without any mitochondrion. Yet, questions remain about whether this extends beyond the single species and how th ...

Public Library Science2023

Housing, street and health: a new systemic research framework

Stéphane Joost, Paola Viganò, Catarina Wall Gago, Anna Pagani, Derek Pierre Christie, Dusan Licina, Valentin Daniel Maurice Bourdon, Idris Guessous, Mathias Lerch

As the world’s population grows in cities, urban dwellers spend a large amount of time inside their home, making housing health ever more important. Critical for residents’ health, the interactions between indoor residential environments and outdoor enviro ...

2023

Landscapes of DNA Mechanics and Genomes

Thomas Antonin Zwahlen

The local physical properties - such as shape and flexibility - of the DNA double-helix is today widely believed to be influenced by nucleic acid sequence in a non-trivial way. Furthermore, there is strong evidence that these properties play a role in many ...

EPFL2023

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