Methodological consensus on clinical proton MRS of the brain: Review and recommendations

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Publications associées (31)

How Energy Metabolism Supports Cerebral Function: Insights from 13C Magnetic Resonance Studies In vivo

Rolf Gruetter, João Miguel das Neves Duarte, Sarah Catherine Sonnay

Cerebral function is associated with exceptionally high metabolic activity, and requires continuous supply of oxygen and nutrients from the blood stream. Since the mid-20th century the idea that brain energy metabolism is coupled to neuronal activity has e ...

Frontiers Research Foundation2017

Technical and experimental features of Magnetic Resonance Spectroscopy of brain glycogen metabolism

Rolf Gruetter, Hongxia Lei, Ana Francisca Leal Silva Soares

In the brain, glycogen is a source of glucose not only in emergency situations but also during normal brain activity. Altered brain glycogen metabolism is associated with energetic dysregulation in pathological conditions, such as diabetes or epilepsy. Bot ...

Elsevier2017

Creatine in the central nervous system: From magnetic resonance spectroscopy to creatine deficiencies

Cristina Ramona Cudalbu, Veronika Rackayová

Creatine (Cr) is an important organic compound acting as intracellular high-energy phosphate shuttle and in energy storage. While located in most cells where it plays its main roles in energy metabolism and cytoprotection, Cr is highly concentrated in musc ...

Elsevier2017

Study of cortical energy metabolism during sensory stimulation-induced brain activity by ¹³C magnetic resonance spectroscopy in vivo

Sarah Catherine Sonnay

Cerebral function is associated with high metabolic activity that is supported by continuous supply of oxygen and glucose from the blood. Coupling between brain energy metabolism and neuronal activity has been studied extensively during the past decades. N ...

EPFL2017

Diagnostic approaches to predict persistent post-traumatic symptoms after mild traumatic brain injury - a literature review

Jean-Philippe Thiran, Alessandro Daducci

Mild traumatic brain injury (mTBI) is one of the most frequently diagnosed neurological disorders in emergency departments. Although there are established recommendations for the diagnosis and treatment in the acute stage, there is an on-going debate in wh ...

Taylor & Francis Ltd2016

(1)H and (31)P magnetic resonance spectroscopy in a rat model of chronic hepatic encephalopathy: in vivo longitudinal measurements of brain energy metabolism

Bernard Lanz, Cristina Ramona Cudalbu, Corina Mihaela Berset, Veronika Rackayová

Chronic liver disease (CLD) leads to a spectrum of neuropsychiatric disorders named hepatic encephalopathy (HE). Even though brain energy metabolism is believed to be altered in chronic HE, few studies have explored energy metabolism in CLD-induced HE, and ...

Springer Verlag2016

Improved surface coil design and pulse sequence development for in vivo 13C MR spectroscopy of humans at 7T

Eulalia Serés Roig

Nuclear magnetic resonance (NMR) is a non-invasive tool for the study of human diseases. In particular, carbon-13 magnetic resonance spectroscopy (13C MRS) is a promising derivative tool for investigating metabolism in vivo, as it allows the non-invasive m ...

EPFL2015

Numerical Assessment of Brain Stroke Follow-Up via Differential Microwave Imaging

Juan Ramon Mosig, Michael Mattes, Mina Bjelogrlic

This paper proposes a numerical assessment of brain stroke follow-up via differential Microwave Imaging. The aim is to follow the evolution of the patient’s stroke growth and location, in order to support decisions in the clinical treatment. We present a f ...

2015

B1+-mapping and B1+ inhomogeneity correction at high field

Florent Eggenschwiler

Magnetic resonance images acquired at the highest strength of the main magnetic field B0 are of interest since they highly benefit from an increased signal to noise ratio. At ultra high field strengths (B0 > 7 Tesla) images with more contrast and higher re ...

EPFL2015

Advanced magnetic resonance spectroscopy and imaging techniques applied to brain development and animal models of perinatal injury

Yohan Van de Looij

Magnetic resonance spectroscopy (MRS) and magnetic resonance imaging (MRI) are widely used in the field of brain development and perinatal brain injury. Due to technical progress the magnetic field strength (B0) of MR systems has continuously increased, fa ...

Elsevier2015

Brain energy metabolism measured by 13C magnetic resonance spectroscopy in vivo upon infusion of [3-13C]lactate

Rolf Gruetter, João Miguel das Neves Duarte, Freya-Merret Girault

The brain uses lactate produced by glycolysis as an energy source. How lactate originated from the blood stream is used to fuel brain metabolism is not clear. The current study measures brain metabolic fluxes and estimates the amount of pyruvate that becom ...

Wiley-Blackwell2015

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