Publications associées à Visual masking deficits in schizophrenia: a view into the genetics of the disease through an endophenotype

Publications associées (19)

Disorder-assisted real–momentum topological photonic crystal

Romain Christophe Rémy Fleury, Haoye Qin, Zhe Zhang, Ji Zhou, Bo Li

Topological defects and disorder counteract each other. Intuitively, disorder is considered detrimental, requiring efforts to mitigate its effects in conventional topological photonics. We propose a counter-intuitive approach that exploits a real–momentum ...

Springer Science and Business Media LLC2025

The genetic architecture of multimodal human brain age

Aleix Boquet I Pujadas

The complex biological mechanisms underlying human brain aging remain incompletely understood. This study investigated the genetic architecture of three brain age gaps (BAG) derived from gray matter volume (GM-BAG), white matter microstructure (WM-BAG), an ...

Nature Portfolio2024

What we learn about bipolar disorder from large-scale neuroimaging: Findings and future directions from theENIGMABipolar Disorder Working Group

Erick Jorge Canales Rodriguez, Jorge Miguel Dias Almeida Rodrigues Soares

MRI-derived brain measures offer a link between genes, the environment and behavior and have been widely studied in bipolar disorder (BD). However, many neuroimaging studies of BD have been underpowered, leading to varied results and uncertainty regarding ...

Wiley2022

Neuromodulation of neocortical microcircuitry: a multi-scale framework to model the effects of cholinergic release

Cristina Colangelo

Neuromodulation of neocortical microcircuits is one of the most fascinating and mysterious aspects of brain physiology. Despite over a century of research, the neuroscientific community has yet to uncover the fundamental biological organizing principles un ...

EPFL2022

Quantum electronic transport across 'bite' defects in graphene nanoribbons

Oleg Yazyev, Michele Pizzochero, Kristians Cernevics

On-surface synthesis has recently emerged as an effective route towards the atomically precise fabrication of graphene nanoribbons (GNRs) of controlled topologies and widths. However, whether and to what degree structural disorder occurs in the resulting s ...

IOP PUBLISHING LTD2021

Theory of intrinsic propagation losses in topological edge states of planar photonic crystals

Juan Pablo Vasco Cano

Using a semianalytic guided-mode expansion technique, we present theory and analysis of intrinsic propagation losses for topological photonic crystal slab waveguide structures with modified honeycomb lattices of circular or triangular holes. Although conve ...

AMER PHYSICAL SOC2020

Psychotropic drug-induced genetic-epigenetic modulation of CRTC1 gene is associated with early weight gain in a prospective study of psychiatric patients

Johannes Gräff, Jose Vicente Sanchez Mut

Background: Metabolic side effects induced by psychotropic drugs represent a major health issue in psychiatry. CREB-regulated transcription coactivator 1 (CRTC1) gene plays a major role in the regulation of energy homeostasis and epigenetic mechanisms may ...

2019

Electrophysiological correlates of visual backward masking in first-episode psychosis

Michael Herzog, Maya Roinishvili, Albulena Jashari-Shaqiri, Janir Nuno Ramos Antunes Da Cruz, Ophélie Gladys Favrod

Schizophrenia is a heterogeneous disorder and among other symptoms, patients have important visual impairments. Visual paradigms are therefore important tools to investigate the mechanisms of schizophrenia. We have previously shown that visual backward mas ...

2017

SQC: Secure Quality Control for Meta-Analysis of Genome-Wide Association Studies

Jean-Pierre Hubaux, Jacques Fellay, Zhicong Huang, Huang Lin

Motivation: Due to the limited power of small-scale genome-wide association studies (GWAS), researchers tend to collaborate and establish a larger consortium in order to perform large-scale GWAS. Genome-wide association meta-analysis (GWAMA) is a statistic ...

Oxford University Press2017

The HDAC inhibitor SAHA improves depressive-like behavior of CRTC1-deficient mice: Possible relevance for treatment-resistant depression

Pierre Magistretti

Major depression is a highly complex disabling psychiatric disorder affecting millions of people worldwide. Despite the availability of several classes of antidepressants, a substantial percentage of patients are unresponsive to these medications. A better ...

Elsevier2016

Implication of individual differences in glucocorticoid responsiveness to stress in the development of psychopathology-like behaviour and underlying neurobiology

Sophie Elizabeth Walker

The period around puberty is a critical window in development. It is a time of neuroendocrine and neuroanatomical lability, rendering individuals highly sensitive to stress. Indeed, early adversity increases risk for psychopathology. The mechanisms via whi ...

EPFL2016

Hi YouTube! Personality Impressions and Verbal Content in Social Video

Daniel Gatica-Perez, Joan Isaac Biel Tres, John David Scott Dines

Despite the evidence that social video conveys rich human personality information, research investigating the automatic prediction of personality impressions in vlogging has shown that, amongst the Big-Five traits, automatic nonverbal be- havioral cues are ...

2013

Effect of hole-shape irregularities on photonic crystal waveguides

Vincenzo Savona, Momchil Minkov

The effect of irregular hole shape on the spectrum and radiation losses of a photonic crystal waveguide is studied using Bloch-mode expansion. Deviations from a circular hole are characterized by a radius fluctuation amplitude and correlation angle. It is ...

Optical Society of America2012

Design and User Perception Issues for Personality-Engaged Recommender Systems

Rong Hu

Recommender systems have emerged, as an intelligent information filtering tool, to help users effectively identify information items of interest from a set of overwhelming choices and provide personalized services. Most recommendation technologies typicall ...

EPFL2012

Correlated Optical and Electrical Single-Molecule Measurements Reveal Conformational Diffusion from Ligand Binding to Channel Gating in the Nicotinic Acetylcholine Receptor

Horst Arthur Vogel, Rudolf Hovius, Davor Kosanic

Wiley-Blackwell2011

Association of Candidate Genes with Phenotypic Traits Relevant to Anorexia Nervosa

Pierre Magistretti

This analysis is a follow-up to an earlier investigation of 182 genes selected as likely candidate genetic variations conferring susceptibility to anorexia nervosa (AN). As those initial case-control results revealed no statistically significant difference ...

2011

Learning, Stress and the Role of Personality Profiles in Rats

Maria del Carmen Sandi Perez, Basira Salehi

Stress has been shown to modulate many aspects of physiology and behavior. In particular, substantial work has confirmed that stress is a strong modulator of learning and memory processes. It is more than a century that Yerkes and Dodson have shown that re ...

EPFL2010

Electrophysiology and fluorescence microscopy of ligand-gated ion channels

Christoph Schreiter

The thesis presented here describes studies of ligand binding, function, and arrangement of ligand-gated ion channels in cell membranes. Fluorescence microscopy and the patch clamp technique are used to investigate the nicotinic acetylcholine receptor and ...

EPFL2005

Electronic properties of carbon nanotubes : combined effect of geometry and correlations

Thomas Gloor

In this thesis we study the interplay between electronic correlations and geometry in single-walled carbon nanotubes by microscopic model calculations. Electronic correlations are expected to be strong because of the low dimensionality of carbon nanotubes. ...

EPFL2005