Proliferation-driven mechanical compression induces signalling centre formation during mammalian organ development

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Porous rocks have long been the focus of intense research driven by their importance in our society as host to our most essential resources (oil, gas, water, geothermal energy, etc), yet their rheology remains poorly understood. With increasing depth, poro ...

Adipose tissue is a key metabolic and highly-dynamic organ whose dysregulation may cause clinical conditions of concern such as obesity and lipodystrophy. Its function varies based on the anatomy, in fact, visceral adipose tissue expansion carries a greate ...

The stress state is an important parameter in terms of both earthquake nucleation and rupture. Here, a new stimulation technique is proposed for Enhanced Geothermal Systems (EGSs), which have previously been burdened with a number of high-profile incidence ...

Chimeric antigen receptors (CARs) are synthetic, transmembrane proteins that trigger immune cell signaling following their engagement. They have been first utilized in T cells and later in natural killer (NK) cells to redirect their cytotoxicity toward a s ...

Superionics are fascinating materials displaying both solid- and liquid-like characteristics: as solids, they respond elastically to shear stress; as liquids, they display fast-ion diffusion at normal conditions. In addition to such scientific interest, su ...

The ratio of nuclear content to cytoplasmic volume (N/C ratio) is a key regulator driving the maternal-to -zy-gotic transition in most animal embryos. Altering this ratio often impacts zygotic genome activation and de-regulates the timing and outcome of em ...

Glutathione (GSH) is the main determinant of intracellular redox potential and participates in multiple cellular signalling pathways. Achieving a detailed understanding of intracellular GSH homeostasis depends on the development of tools to map GSH compart ...

Prequalified beam-to-column connections in steel moment resisting frames usually concentrate inelastic deformations in the steel beam ends. As such, nonlinear geo-metric instabilities (i.e., local buckling) may occur in these regions at modest lateral drif ...

Proliferation-driven mechanical compression induces signalling centre formation during mammalian organ development

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Bounding the localized to ductile transition in porous rocks: implications for geo-reservoirs

Cross-anatomical single-cell definition and characterization of human adipose progenitor niche

Single-Well Pore Pressure Preconditioning for Enhanced Geothermal System Stimulation

Unlocking Hidden Potential: Exploring the Complexities of Signaling in Immune Cell Activation to Optimize CAR Therapy

Solids that are also liquids: elastic tensors of superionic materials

The nuclear-to-cytoplasmic ratio drives cellularization in the close animal relative Sphaeroforma arctica

A locally activatable sensor for robust quantification of organellar glutathione

Geometric tolerances of welded connections with inelastic panel zones