Publications associées à Copper-Catalyzed Oxyalkynylation of C-S Bonds in Thiiranes and Thiethanes with Hypervalent Iodine Reagents

Learning Transformations To Reduce the Geometric Shift in Object Detection

Mathieu Salzmann, Martin Pierre Engilberge, Vidit Vidit

The performance of modern object detectors drops when the test distribution differs from the training one. Most of the methods that address this focus on object appearance changes caused by, e.g., different illumination conditions, or gaps between syntheti ...

Ieee Computer Soc2023

Synthesis and Applications of Ynimines and Enantioselective Total Synthesis of Artatrovirenol A

Rémi Hugo Lavernhe

The first chapter of this thesis describe the development of a general synthesis of ynimines, an under-exploited motif in organic chemistry. In the presence of an inexpensive copper catalyst and 2,2'-biquinoline, reaction of easily accessible O-acyloximes ...

EPFL2023

Radical Alkynylations with EthynylBenziodoXolones: From Photocatalysis to Direct Excitation

Jérôme Waser, Stephanie Grace Elizabeth Amos

Ethynylbenziodoxolones (EBXs) have recently emerged as potent reagents for the alkynylation of radicals. Their combination with photocatalysis allows the synthesis of valuable alkynes at room temperature. Herein, we discuss two photomediated strategies for ...

2022

Exploring Photoredox-Catalyzed (Re)functionalizations with Core-Modified Benziodoxolones

Jérôme Waser, Franck Le Vaillant, Stephanie Grace Elizabeth Amos

Alkynes and nitriles are valuable building blocks in organic synthesis and also have multiple applications in chemical biology and materials science. Due to the high availability of tertiary alcohols, developing methods for their conversion into alkynes an ...

2022

Synthetic Studies toward Amanita Phalloides Toxins

Philipp Georg Werner Seeberger

Amatoxins are ribosomally synthesized and post-translationally modified bicyclic octapeptides biosynthesized by the deadly basidiomycete fungus Amanita phalloides. Amongst this group, alpha-amanitin is the most widely known toxin and is currently under inv ...

EPFL2020

Palladium Catalysed Intramolecular Carbo-oxygenation of Propargylic Amines to Access 1,2-Amino Alcohols and alpha-Amino Ketones via in situ Tether Formation

Phillip Gulliver Dominic Greenwood

a-Amino ketones and 1,2-amino alcohols are important structural motifs in organic chemistry, that can be observed in natural products, pharmaceutically and bioactive compounds. For these reasons, they constitute privileged targets for the development of ne ...

EPFL2020

Photochemical Functionalization of Heterocycles with EBX Reagents: C-H Alkynylation versus Deconstructive Ring Cleavage

Jérôme Waser, Marion Marie-Agnès Garreau

The development of novel methodologies for the functionalization of saturated heterocycles is highly desirable. Herein, we report a cheap and efficient photochemical method for the C-H functionalization of saturated O-heterocycles, as well as the deconstru ...

2020

Catalytic Enantioselective Transformations with Chiral Cyclopentadienyl Ruthenium(II) Complexes

Sung Hwan Park

The chemistry of cyclopentadienyl ruthenium(II) complexes plays an important role in ruthenium catalysis because of its high potential for various transformations. However, asymmetric catalysis with chiral cyclopentadienyl ruthenium(II) complexes is still ...

EPFL2020

Complements to Mugge and Friedel's Theory of Twinning

Cyril Cayron

The crystallography of twinning is based on the concepts of simple shear and obliquity introduced by Mugge, Mallard and Friedel at the turn of the last century, with tensor mathematics later developed by Bilby, Bevis and Crocker in the 1960s. We propose a ...

2020

Development of New Strategies of Umpolung with Cyclic Hypervalent Iodine Reagents

Paola Caramenti

Organic chemistry is essential for the development of a modern society and technical progress requires the continuous development of synthetic methodologies Novel, efficient, selective and flexible protocols are employed to access complex frameworks from s ...

EPFL2019

Geometric robustness of deep networks: analysis and improvement

Pascal Frossard, Seyed Mohsen Moosavi Dezfooli, Can Kanbak

Deep convolutional neural networks have been shown to be vulnerable to arbitrary geometric transformations. However, there is no systematic method to measure the invariance properties of deep networks to such transformations. We propose ManiFool as a simpl ...

2018

Oxidation Processes in Water Treatment: Are We on Track?

Urs von Gunten

Chemical oxidants have been applied in water treatment for more than a century, first as disinfectants and later to abate inorganic and organic contaminants. The challenge of oxidative abatement of organic micropollutants is the formation of transformation ...

2018

Investigations of the Chemistry of 1-Alkynyltriazenes

Florian Gérald Abela

The chemistry of aromatic triazenes is well known, and has been explored for more than a century. These compounds have emerged as very useful intermediates, because of their unique reactivity. This functionality can notably be used to access many other fun ...

EPFL2018

Shape Projectors for Landmark-Based Spline Curves

Michaël Unser, Daniel Andreas Schmitter

We present a generic method to construct orthogonal projectors for two-dimensional landmark-based parametric spline curves. We construct vector spaces that define a geometric transformation (e.g., affine, similarity, and scaling) that is applied to a refer ...

IEEE Institute of Electrical and Electronics Engineers2017

How Computer Science Risks to Lose its Innocence, and Should Attempt to Take Responsibility

Karl Aberer

Computer science is playing a driving role in transforming today's society through information technology. In this transformation we observe power shifts increasingly strengthening centralised organisations, which are negatively perceived by many people. W ...

Ieee Computer Soc2017

Projective transformations of structural equilibrium

Corentin Jean Dominique Fivet

Direct methods that transform the geometry of a structure and conserve its static equilibrium are of particular interest for designers. They allow the exploration of alternative solutions at minimum computational cost. While parallel transformations (stret ...

2016

Local Geometric Transformations in Image Analysis

Zsuzsanna Püspöki

The characterization of images by geometric features facilitates the precise analysis of the structures found in biological micrographs such as cells, proteins, or tissues. In this thesis, we study image representations that are adapted to local geometric ...

EPFL2016

Catalytic C-C Bond Activations via Oxidative Addition to Transition Metals

Nicolai Cramer, Laetitia Marie Mélanie Souillart

Selective cleavages of carbon-carbon bonds catalyzed by transition-metal complexes have been shown to be increasingly versatile tools for organic synthesis allowing for complementary synthetic strategies. Numerous examples of transition-metal catalyzed C-C ...

Amer Chemical Soc2015

Robust Image Reconstruction from Multiview Measurements

Pierre Vandergheynst, Gilles Puy

We propose a novel method to accurately reconstruct a set of images representing a single scene from a few linear multiview measurements. Each observed image is modeled as the sum of a background image and a foreground one. The background image is common t ...

Siam Publications2014

Semisupervised Manifold Alignment of Multimodal Remote Sensing Images

Devis Tuia, Maxime Pierre Trolliet

We introduce a method for manifold alignment of different modalities (or domains) of remote sensing images. The problem is recurrent when a set of multitemporal, multisource, multisensor, and multiangular images is available. In these situations, images sh ...

Ieee-Inst Electrical Electronics Engineers Inc2014