Dopamine Dynamics in Reward-based Learning

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Over the past decade, research has shown that the primary motor cortex (M1), the brain's main output for movement, also responds to rewards. These reward signals may shape motor output in its final stages, influencing movement invigoration and motor learni ...

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Dopamine synapses play a crucial role in volitional movement and reward-related behaviors, while dysfunction of dopamine synapses causes various psychiatric and neurological disorders. Despite this significance, the true biological nature of dopamine synap ...

Aversively-motivated associative learning allows animals to avoid harm and thus ensures survival. Aversive learning can be studied by the fear learning paradigm, in which an innocuous sensory stimulus like a tone (conditioned stimulus, CS), acquires a nega ...

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Reinforcement learning (RL) is crucial for learning to adapt to new environments. In RL, the prediction error is an important component that compares the expected and actual rewards. Dopamine plays a critical role in encoding these prediction errors. In my ...

Information derived from experiences is incorporated into the brain as changes to ensembles of cells, termed engram cells, which allow memory storage and recall. The mechanism by which those changes hold specific information is unclear. Here, we test the h ...

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Model-free Reinforcement Learning (RL) generally suffers from poor sample complexity, mostly due to the need to exhaustively explore the state-action space to find well-performing policies. On the other hand, we postulate that expert knowledge of the syste ...

Dopamine Dynamics in Reward-based Learning

Chattez avec Graph Search

Application of Deep Learning and Geospatial Analysis in Soil Loss Risk in the Moulouya Watershed, Morocco

Image steganalysis using active learning and hyperparameter optimization

Reward signals in the motor cortex: from biology to neurotechnology

Striatal Dopamine Signals and Reward Learning

GABAergic-like dopamine synapses in the brain

Plasticity of sensory representations in the posterior insular cortex during fear learning

Mitofusin-2 in nucleus accumbens D2-MSNs regulates social dominance and neuronal function

A striatal circuit balances learned fear in the presence and absence of sensory cues

Longitudinal evaluation of the mechanisms supporting post-stroke motor recovery using TMS-EEG coupling

Linking connectivity of deep brain stimulation of nucleus accumbens area with clinical depression improvements: a retrospective longitudinal case series

Acute TNF alpha levels predict cognitive impairment 6-9 months after COVID-19 infection

Unveiling the complexity of learning and decision-making

Engram cell connectivity as a mechanism for information encoding and memory function

Involvement of prelimbic cortex neurons and related circuits in the acquisition of a cooperative learning by pairs of rats

Non-invasive stimulation of the human striatum disrupts reinforcement learning of motor skills

A theory of memory consolidation and synaptic pruning in cortical circuits

Principles of Network Plasticity in Neocortical Microcircuits

White adipose tissue distribution and amount are associated with increased white matter connectivity

Seeking the new, learning from the unexpected: Computational models of surprise and novelty in the brain

Computationally Efficient Reinforcement Learning: Targeted Exploration leveraging Simple Rules