Probing Rotational and Translational Diffusion of Nanodoublers in Living Cells on Microsecond Time Scales

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Molecular machines offer many opportunities for the development of responsive materials and introduce autono-mous motion in molecular systems. While basic molecular switches and motors carry out one type of motion upon being exposed to an external stimulus ...

An acoustic dimer composed of two electronically controlled electroacoustic resonators is presented with the view of exploring one-dimensional topological phenomena. Active control allows real-time manipulation of the metamaterial’s properties, including i ...

The evolution of the 3D morphology is at the center of many relevant biological processes ranging from cellular differentiation to cancer invasion and metastasis. Microscopy techniques, such as electron microscopy (EM), super-resolution (SR) optical micros ...

In this paper, we propose a novel center-based decoupled point cloud registration framework for robust 6D object pose estimation in real-world scenarios. Our method decouples the translation from the entire transformation by predicting the object center an ...

Proteins, the central building blocks of life, play pivotal roles in nearly every biological function. To do so, these macromolecular structures interact with their surrounding environment in complex ways, leading to diverse functional behaviors. The predi ...

Structure determination techniques are an essential tool to investigate and understand molecules, especially in biology, where functionality crucially depends on structure. The dominant high-resolution methods, such as transmission electron microscopy and ...

Repairing articular osteochondral defects present considerable challenges in self-repair due to the complex tissue structure and low proliferation of chondrocytes. Conventional clinical therapies have not shown significant efficacy, including microfracture ...

Single-walled carbon nanotubes (SWCNTs) have unique optoelectronic properties that make them suitable for applications ranging from phototherapy to imaging and sensing, but their uptake has mainly been explored in eukaryotic cells. Here the authors explore ...

Chromatin is spatially organized into functional states that are defined by both the presence of specific histone post-translational modifications (PTMs) and a defined set of chromatin-associated “reader” proteins. Different models for the underlying mecha ...

Single-particle tracking and optical tweezers are powerful techniques for studying diverse processes at the microscopic scale. The stochastic behavior of a microscopic particle contains information about its interaction with surrounding molecules, and an o ...

Cell-free biology is increasingly utilized for engineering biological systems, incorporating novel functionality, and circumventing many of the complications associated with cells. The central dogma describes the information flow in biology consisting of t ...

The activation of memory T cells is a very rapid and concerted cellular response that requires coordination between cellular processes in different compartments and on different time scales. In this study, we use ribosome profiling and deep RNA sequencing ...

To adapt mitochondrial function to the ever-changing intra- and extracellular environment, multiple mitochondrial stress response (MSR) pathways, including the mitochondrial unfolded protein response (UPRmt), have evolved. However, how the mitochondrial st ...

Thanks to recent advancements in synthetic biology, the dream of creating a synthetic cell has become feasible. However, due to its inherent complexity, one of the fundamental functions of all living systems, i.e., self-replication, remains to be introduce ...

The design of efficient energy systems, through the development of new technologies and the improvement of current ones, requires the use of rigorous process synthesis methods for generating and analysing design alternatives. We introduce a digital twin of ...

Probing Rotational and Translational Diffusion of Nanodoublers in Living Cells on Microsecond Time Scales

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Coupled Rotary and Oscillatory Motion in a Second-Generation Molecular Motor Pd Complex

Active Acoustic Su-Schrieffer-Heeger-Like Metamaterial

Time-Resolved Scanning Ion Conductance Microscopy and Single-Molecule Spectroscopy

Center-Based Decoupled Point Cloud Registration for 6D Object Pose Estimation

A Geometric Transformer for Structural Biology: Development and Applications of the Protein Structure Transformer

Low-energy Electron Holography Microscope for Imaging of Single Molecules

Bioinspired gradient scaffolds for osteochondral tissue engineering

Carbon nanotube uptake in cyanobacteria for near-infrared imaging and enhanced bioelectricity generation in living photovoltaics

Multivalent Peptide Ligands To Probe the Chromocenter Microenvironment in Living Cells

Probing Surfactant Bilayer Interactions by Tracking Optically Trapped Single Nanoparticles

Biochemistry of Aminoacyl tRNA Synthetase and tRNAs and Their Engineering for Cell-Free and Synthetic Cell Applications

A Rapid Translational Immune Response Program in CD8 Memory T Lymphocytes

V-ATPase/TORC1-mediated ATFS-1 translation directs mitochondrial UPR activation in C. elegans

Towards an artificial cell: Development of a system which self-regenerates the protein components of the PURE system in microfluidic reactors

Overcoming decision paralysis—A digital twin for decision making in energy system design