Pharmacological and biochemical assessment of γ-secretase-mediated APP processing involved in Alzheimer's disease

Mitko Dimitrov
2014
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Mitko Dimitrov
2014
Theses

Source officielle

Publications associées (12)

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https://infoscience.epfl.ch/entities/publication/02c274a9-2ca8-4a95-9294-775327bca632

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Publications associées (12)

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Neurodegenerative disorders are characterized by the brain deposition of insoluble amyloidogenic proteins, such as alpha-synuclein or Tau, and the concomitant deterioration of cell functions such as the autophagy-lysosomal pathway (ALP). The ALP is involve ...

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Activin-A is a Transforming Growth Factor-B (TGFB)-related cytokine that regulates various biological processes including cell proliferation and differentiation through autocrine, paracrine or endocrine signaling. Activin-A expression is upregulated in mul ...

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