Publications associées à Assessment of shear stress related parameters in the carotid bifurcation using mouse-specific FSI simulations

Novel theory and potential applications of central diastolic pressure decay time constant

Nikolaos Stergiopoulos, Patrick Segers, Vasiliki Bikia, Georgios Rovas, Sokratis Anagnostopoulos

Central aortic diastolic pressure decay time constant ( ) is according to the two-element Windkessel model equal to the product of total peripheral resistance (R) times total arterial compliance (C ). As such, it is related to arterial stiffness, which has ...

2024

Reduced order modeling of parametrized pulsatile blood flows: Hematocrit percentage and heart rate

Ricardo Reyes Sotomayor

This paper numerically evaluates the accuracy and performance of a stabilized finite element Reduced Order Modelling (ROM) approach that is designed to simulate pulsatile blood flows. The method is able to estimate fluid flow parametric solutions of intere ...

PERGAMON-ELSEVIER SCIENCE LTD2023

On the similarity between aortic and carotid pressure diastolic decay: a mathematical modelling study

Nikolaos Stergiopoulos, Vasiliki Bikia, Georgios Rovas, Sokratis Anagnostopoulos

Aortic diastolic pressure decay (DPD) has been shown to have considerable pathophysiological relevance in the assessment of vascular health, as it is significantly affected by arterial stiffening. Nonetheless, the aortic pressure waveform is rarely availab ...

Nature Portfolio2023

Influence of Viscous Lubricant on Nucleation and Propagation of Frictional Ruptures

Marie Estelle Solange Violay, François Xavier Thibault Passelègue, Federica Paglialunga

Fluids are pervasive in the Earth's crust and saturate fractures and faults. The combination of fluids and gouge layers developing along faults can generate fluids of different viscosities. Such viscous fluids were found to influence the reactivation, fric ...

2023

Compliance-matching vascular grafts with personalization potential

Georgios Rovas

Aortic diseases are characterized by dire prognosis and inadequate diagnosis, owing to their insidious yet lethal nature. Aortopathies, namely aortic aneurysms and dissections, along with certain congenital diseases, might necessitate surgical replacement ...

EPFL2023

lifex-cfd: An open-source computational fluid dynamics solver for cardiovascular applications

Alfio Quarteroni, Luca Dede', Marco Fedele

Computational fluid dynamics (CFD) is an important tool for the simulation of the cardiovascular function and dysfunction. Due to the complexity of the anatomy, the transitional regime of blood flow in the heart, and the strong mutual influence between the ...

Elsevier2023

Study of backward Brillouin scattering in gas-filled anti-resonant fibers

Luc Thévenaz, Li Zhang, Malak Mohamed Hossameldeen Omar Mohamed Galal

Brillouin scattering in gas shows unmatched gain properties in hollow-core optical fibers filled at high pressure. Here, the gain characteristics are studied for two common gases, namely, N2 and CO2, which show distinct features and are compared to expecte ...

2023

Permeability sets the linear path instability of buoyancy-driven disks

François Gallaire, Pier Giuseppe Ledda, Giuseppe Antonio Zampogna, Giovanni Vagnoli

The prediction of trajectories of buoyancy-driven objects immersed in a viscous fluid is a key problem in fluid dynamics. Simple-shaped objects, such as disks, present a great variety of trajectories, ranging from zig-zag to tumbling and chaotic motions. Y ...

Cambridge University Press2023

Drained Clay-Pipe Interface Resistance at Low Normal Stresses and Elevated Temperatures

Roba Houhou

Offshore pipelines that transport hydrocarbons under high pressure and high temperature are usually thermally insulated to maintain an elevated temperature and prevent any heat loss to the surroundings. However, the temperatures at the outer-wall of the pi ...

AMER SOC CIVIL ENGINEERS2023

Polygenic Risk Scores for Prediction of Subclinical Coronary Artery Disease in Persons Living With HIV: The Swiss HIV Cohort Study

Jacques Fellay, Christian Axel Wandall Thorball

Background. In people living with human immunodeficiency virus (HIV) (PLWH), individual polygenic risk scores (PRSs) are associated with coronary artery disease (CAD) events. Whether PRSs are associated with subclinical CAD is unknown. ...

OXFORD UNIV PRESS INC2022

Sub-micrometer morphology of human atherosclerotic plaque revealed by synchrotron radiation-based mu CT-A comparison with histology

Anne Bonnin, Goran Lovric

Histology is a long standing and well-established gold standard for pathological characterizations. In recent years however, synchrotron radiation-based micro-computed tomography (SR mu CT) has become a tool for extending the imaging of two-dimensional thi ...

PUBLIC LIBRARY SCIENCE2022

Effects of the parallel flow shear on the ITG-driven turbulent transport in tokamak plasmas

Yann Camenen, Javier García Hernández, Samuele Mazzi

The impact of the parallel flow shear on the tokamak plasma stability and turbulent transport driven by the ion temperature gradient (ITG) modes is analyzed by means of local gyrokinetic numerical analyses. It is shown that the parallel flow shear increase ...

IOP Publishing Ltd2022

Eulerian simulation of complex suspensions and biolocomotion in three dimensions

Yuexia Luna Lin

We present a numerical method specifically designed for simulating three-dimensional fluid-structure interaction (FSI) problems based on the reference map technique (RMT). The RMT is a fully Eulerian FSI numerical method that allows fluids and large-deform ...

National Academy of Sciences2022

p-Aminobenzamidine attenuates cardiovascular dysfunctions in spontaneously hypertensive rats

Nikolaos Stergiopoulos, Fabiana Pereira Da Costa Fraga, Allancer Divino De Carvalho Nunes

Aims:Diminazene aceturate, a putative ACE2 activator, is susceptible to cleavage resulting in the formation of paminobenzamidine (PAB). This study aimed to investigate the effects of PAB in addressing cardiovascular dysfunctions in spontaneously hypertensi ...

PERGAMON-ELSEVIER SCIENCE LTD2022

Friction Induces Anisotropic Propulsion in Sliding Magnetic Microtriangles

Ignacio Pagonabarraga Mora

In viscous fluids, motile microentities such as bacteria or artificial swimmers often display different transport modes than macroscopic ones. A current challenge in the field aims at using friction asymmetry to steer the motion of microscopic particles. H ...

AMER CHEMICAL SOC2022

Experimental quantification of 3D deformations in sensitive clay during stress-probing

Edward Carlo Giorgio Andò

Unique four-dimensional (4D) deformation data are collected during drained triaxial tests on intact specimens of a natural sensitive clay. This requires the development of a miniature triaxial cell for advanced stress path testing, specifically designed fo ...

ICE PUBLISHING2022

Effects of velocity-dependent apparent toughness on the pre- and post-shut-in growth of a hydraulic fracture

Dong Liu, Guanyi Lu

We investigate the growth of a plane-strain/radial hydraulic fracture in an infinite impermeable medium driven by a constant injection rate assuming that the apparent toughness scales with the decreasing fracture growth rate in a power-law relation. The vi ...

ELSEVIER SCI LTD2022

Determination of Parameters Characteristic of Dynamic Weakening Mechanisms During Seismic Faulting in Cohesive Rocks

Marie Estelle Solange Violay, Chiara Cornelio, François Xavier Thibault Passelègue

While sliding at seismic slip-rates of ∼1 m/s, natural faults undergo an abrupt decrease of shear stress called dynamic weakening. Asperity-scale processes related to flash heating and weakening and, meso-scale (mm-cm) processes involving shear across the ...

AGU2022

Three-dimensional stress state during dynamic shear rupture propagation along frictional interfaces in elastic plates

Jean-François Molinari, Roozbeh Rezakhani

The state of stress in plates, where one geometric dimensions is much smaller than the others, is often assumed to be of plane stress. This assumption is justified by the fact that the out-of-plane stress components are zero on the free-surfaces of a plate ...

ELSEVIER2022

Ultra-high voltage, low power and energy recovering electronics for dielectric elastomer actuators

Raphaël Johannes Charles Mottet

Heart failure is a cardiovascular disease affecting between 1 and 2% of the population of developed countries alone - more than 10 million people - with this number bound to increase due to the ageing of the population. This condition starts to develop its ...

EPFL2022