Publications associées à One Fuzz Doesn’t Fit All: Optimizing Directed Fuzzing via Target-tailored Program State Restriction

Model reduction of coupled systems based on non-intrusive approximations of the boundary response maps

Jan Sickmann Hesthaven, Niccolo' Discacciati

We propose a local, non -intrusive model order reduction technique to accurately approximate the solution of coupled multi -component parametrized systems governed by partial differential equations. Our approach is based on the approximation of the boundar ...

Elsevier Science Sa2024

On distributional autoregression and iterated transportation

Victor Panaretos, Laya Ghodrati

We consider the problem of defining and fitting models of autoregressive time series of probability distributions on a compact interval of Double-struck capital R. An order-1 autoregressive model in this context is to be understood as a Markov chain, where ...

Wiley2024

Multi-well plate lid for single-step pooling of 96 samples for high-throughput barcode-based sequencing

Bart Deplancke, Daniel Migliozzi, Hüseyin Baris Atakan, Mustafa Demir, Riccardo Dainese, Daniel Alpern, Dariia Gudkova, Gilles Weder

High-throughput transcriptomics is of increasing fundamental biological and clinical interest. The generation of molecular data from large collections of samples, such as biobanks and drug libraries, is boosting the development of new biomarkers and treatm ...

Springer2024

Comparison of Three Viral Nucleic Acid Preamplification Pipelines for Sewage Viral Metagenomics

Tamar Kohn, Xavier Fernandez Cassi

Viral metagenomics is a useful tool for detecting multiple human viruses in urban sewage. However, more refined protocols are required for its effective use in disease surveillance. In this study, we investigated the performance of three different preampli ...

2024

Distributional Regression and Autoregression via Optimal Transport

Laya Ghodrati

We present a framework for performing regression when both covariate and response are probability distributions on a compact and convex subset of

\R^d

. Our regression model is based on the theory of optimal transport and links the conditional Fr'echet m ...

EPFL2023

Bayes-optimal Learning of Deep Random Networks of Extensive-width

Hugo Chao Cui, Florent Gérard Krzakala, Lenka Zdeborová

We consider the problem of learning a target function corresponding to a deep, extensive-width, non-linear neural network with random Gaussian weights. We consider the asymptotic limit where the number of samples, the input dimension and the network width ...

2023

Arvin: Greybox Fuzzing Using Approximate Dynamic CFG Analysis

Sirus Shahini, Mathias Josef Payer

Fuzzing has emerged as the most broadly used testing technique to discover bugs. Effective fuzzers rely on coverage to prioritize inputs that exercise new program areas. Edge-based code coverage of the Program Under Test (PUT) is the most commonly used cov ...

ASSOC COMPUTING MACHINERY2023

Acute TNF alpha levels predict cognitive impairment 6-9 months after COVID-19 infection

Dimitri Nestor Alice Van De Ville, Alessandra Griffa, Alexandre Cionca, Idris Guessous

Background: A neurocognitive phenotype of post-COVID-19 infection has recently been described that is characterized by a lack of awareness of memory impairment (i.e., anosognosia), altered functional connectivity in the brain's default mode and limbic netw ...

PERGAMON-ELSEVIER SCIENCE LTD2023

Reliable uncertainties: Error correlation, rotated error bars, and linear regressions in three-isotope plots and beyond

Reto Georg Trappitsch

Correlated errors of experimental data are a common but often neglected problem in physical sciences. Various tools are provided here for thorough propagation of uncertainties in cases of correlated errors. Discussed are techniques especially applicable to ...

ELSEVIER2023

Optimised set of oligonucleotides for bulk rna barcoding and sequencing

Bart Deplancke, Riccardo Dainese, Daniel Alpern, Vincent Roland Julien Gardeux

The present invention relates generally to the field of nucleic acid sequencing and provides oligonucleotide molecules and barcodes contained therein. These oligonucleotide molecules and barcodes molecules are useful in sequencing to identify and resolve e ...

2023

FISHFUZZ: Catch Deeper Bugs by Throwing Larger Nets

Mathias Josef Payer, Jiayuan Zhang, Yuqing Zhang, Flavio Toffalini, Han Zheng

Fuzzers effectively explore programs to discover bugs. Greybox fuzzers mutate seed inputs and observe their execution. Whenever a seed reaches new behavior (e.g., new code or higher execution frequency), it is stored for further mutation. Greybox fuzzers d ...

Usenix Assoc2023

Semi-Supervised Deep Learning Representations in Earth Observation Based Forest Management

Devis Tuia, Oleg Antropov, Sudipan Saha, Marc Conrad Russwurm, Lloyd Haydn Hughes

In this study, we examine the potential of several self-supervised deep learning models in predicting forest attributes and detecting forest changes using ESA Sentinel-1 and Sentinel-2 images. The performance of the proposed deep learning models is compare ...

The Institute of Electrical and Electronics Engineers, Inc2023

Systematic benchmarking of single-cell ATAC-sequencing protocols

Bart Deplancke, Jörn Pezoldt, Camille Lucie Germaine Lambert

Benchmarking of scATAC-seq protocols demonstrates the effects of data quality on downstream analyses. ...

NATURE PORTFOLIO2023

Electronic readout of DNA amplification in nanoliter chambers. Strategies towards highly parallel semiconductor-based nucleic acid amplification testing

Saurabh Tomar

Polymerase chain reaction (PCR) has been the most significant driver in the field of nucleic acid testing (NAT) since its invention. Popularized as an abbreviation by the Covid-19 pandemic, PCR-based methods are the gold standard in the field of diagnostic ...

EPFL2023

Regressive Tomography and Direct Regressive Reconstruction: A Research Note

Henri Weisen

Two related methods for inverting line-integrated measurements are presented in this research paper in the context of the recent deuterium-tritium experiments in the JET tokamak. Unlike traditional methods of tomography, these methods rely on making use of ...

2023

Modeling, analysis, and design of complex biological networks

Mohammadomid Oftadeh

Automating experimental procedures has resulted in an unprecedented increase in the volume of generated data, which, in turn, has caused an accumulation of unprocessed data. As a result, the need to develop tools to analyze data systematically has been ris ...

EPFL2023

Distribution-on-distribution regression via optimal transport maps

Victor Panaretos, Laya Ghodrati

We present a framework for performing regression when both covariate and response are probability distributions on a compact interval. Our regression model is based on the theory of optimal transportation, and links the conditional Frechet mean of the resp ...

OXFORD UNIV PRESS2022

Minimax rate for optimal transport regression between distributions

Victor Panaretos, Laya Ghodrati

Distribution-on-distribution regression considers the problem of formulating and es-timating a regression relationship where both covariate and response are probability distributions. The optimal transport distributional regression model postulates that th ...

ELSEVIER2022

Genomic Diversity of Torque Teno Virus in Blood Samples from Febrile Paediatric Outpatients in Tanzania: A Descriptive Cohort Study

Mary-Anne Hartley

Torque teno virus (TTV) is considered to be an ubiquitous member of the commensal human blood virome commonly reported in mixed genotype co-infections. This study investigates the genomic diversity of TTV in blood samples from 816 febrile Tanzanian childre ...

MDPI2022

Feature-based no-reference video quality assessment using Extra Trees

Arash Amini, Hatef Otroshi Shahreza

With the emergence of social networks and improvements in the internet speed, the video data has become an ever-increasing portion of the global internet traffic. Besides the content, the quality of a video sequence is an important issue at the user end wh ...

WILEY2022